Kivonat:
In humans the HIV infection results in a chronic disease with a permanent fight
between factors controlling HIV and the escape of the virus. Fromthese control
mechanisms the present review summarizes the role betwen complement and
autoantibodies; the competition of complement and anti-HIV antibodies for binding
sites, the role of mannan-binding lectin in the susceptibility to and in the
survival after HIV infection, the contribution of complement-dependent enhancing
type antibodies to the clinical progression of HIV disease as well as the
changing pattern of some autoantibodies (mimicking MHC class II molecules,
anti-heat shock protein 60 antibodies and anti-C1q antibodies) which were found
to correlate to immunological and clinical parameters.