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  • Instent resztenózis és stent trombózis vizsgálata perkután koronária intervención átesett betegeken 
    Berta, Balázs (2015)
  • Insulin-like growth factor I and its binding protein-3 are regulators of lactation and maternal responsiveness 
    Lékó, András Hugó; Cservenák, Melinda; Szabó, Éva Rebeka; Hanics, János; Alpár, Alán; Dobolyi, Árpád (2017)
    Adaptation to motherhood includes maternal behaviour and lactation during the postpartum period. The major organizing centres of maternal behaviour and lactation are located in the hypothalamic medial preoptic area (MPOA) ...
  • Insulin pump therapy in children with type 1 diabetes: analysis of data from the SWEET registry 
    Szypowska, Agnieszka; Schwandt, Anke; Svensson, Jannet; Shalitin, Shlomit; Cardona-Hernandez, Roque; Forsande, Gun; Sundberg, Frida; Carine De, Beaufor; David, Maahs; Claudio, Maffeis; Stephen MP, O' Riordan; Iveta Dzivite, Krisane; Mauro, Scharf; Sofia, Castro; Maia, Konstantinova; Barbora, Obermannova; Kristina, Casteels; Damla, Gökşen; Júlia, Galhard; Christina, Kanaka-Gantenbein; Birgit, Rami-Merhar; Madácsy, László; The SWEET Study Group (2016)
    BACKGROUND: Intensified insulin delivery using multiple daily injections (MDI) or continuous subcutaneous insulin infusion (CSII) is recommended in children with type 1 diabetes (T1D) to achieve good metabolic control. ...
  • Insulin resistance in an animal model of polycystic ovary disease is aggravated by vitamin D deficiency 
    Hadjad Leila; Várbíró Szabolcs; Horvath Eszter Mária; Monori-Kiss Anna; Pál Éva; Karvaly GB; Heinzlmann, Andrea; Magyar Attila; Szabó István; Sziva RE; Benyó Zoltán; Budai Marianna; Nádasy György László (2018)
    Hyperandrogenic state in females is accompanied with metabolic syndrome, insulin resistance and vascular pathologies. A total of 67%-85% of hyperandrogenic women suffer also from vitamin D deficiency. We aimed to check ...
  • Intact implicit statistical learning in borderline personality disorder 
    Unoka, Zsolt; Vizin Gabriella; Bjelik Anna; Radics Dóra; Németh Dezső; Janacsek Karolina (2017)
    Wide-spread neuropsychological deficits have been identified in borderline personality disorder (BPD). Previous research found impairments in decision making, declarative memory, working memory and executive functions; ...
  • Integrált irányítási rendszer belső auditja az élelmiszeriparban 
    Hortobágyi, Ibolya; Sinka, Magdolna (2020)
  • Integrated analysis of the immunological and genetic status in and across cancer types: impact of mutational signatures beyond tumor mutational burden 
    Budczies Jan; Seidel Anja; Christopoulos Petros; Endris Volker; Kloor Matthias; Győrffy, Balázs; Seliger Barbara; Schirmacher Peter; Stenzinger Albrecht; Denkert Carsten (2018)
    Harnessing the immune system by checkpoint blockade has greatly expanded the therapeutic options for advanced cancer. Since the efficacy of immunotherapies is influenced by the molecular make-up of the tumor and its crosstalk ...
  • Integrated Central Blood Pressure-aortic Stiffness Risk Categories and Cardiovascular Mortality in End-stage Renal Disease 
    Batta, Dóra; Tabák, Ádám; Kőrösi, Beáta; Cseprekál, Orsolya; Egresits, József; Tislér, András; Nemcsik, János (2019)
  • Integrated central blood pressure-aortic stiffness risk score for cardiovascular risk stratification in chronic kidney disease. 
    Nemcsik, János; Tabák, Ádám; Batta, Dóra; Cseprekál, Orsolya; Egresits, J; Tislér, András (2018)
    The aim of this study was to develop an integrated central blood pressure-aortic stiffness (ICPS) risk score to predict cardiovascular events.It was a retrospective cohort study. A total of 100 chronic kidney disease (CKD) ...
  • Integrated (epi)-Genomic Analyses Identify Subgroup-Specific Therapeutic Targets in CNS Rhabdoid Tumors 
    Torchia, Jonathon; Golbourn, Brian; Feng, Shengrui; Ho, King Ching; Sin-Chan, Patrick; Alexandre, Vasiljevic; Joseph, D Norman; Paul, Guilhamon; Livia, Garzia; Natalia, R Agamez; Mei, Lu; Tiffany, S Chan; Daniel, Picard; Pasqualino, de Antonellis; Dong-Anh, Khuong-Quang; Aline, C Planello; Constanze, Zeller; Dalia, Barsyte-Lovejoy; Lucie, Lafay-Cousin; Louis, Letourneau; Mathieu, Bourgey; Man, Yu; Deena, MA Gendoo; Misko, Dzamba; Mark, Barszczyk; Tiago, Medina; Alexandra, N Riemenschneider; A Sorana, Morrissy; Young-Shin, Ra; Vijay, Ramaswamy; Marc, Remke; Christopher, P Dunham; Stephen, Yip; Ho-Keung, Ng; Jian-Qiang, Lu; Vivek, Mehta; Vivek, Mehta; Steffen, Albrecht; Jose, Pimentel; Jennifer, A Chan; Gino, R Somers; Claudia, C Faria; Lucia, Roque; Maryam, Fouladi; Lindsey, M Hoffman; Andrew, S Moore; Yin, Wang; Seung, Ah Choi; Jordan, R Hansford; Daniel, Catchpoole; Diane, K Birks; Nicholas, K Foreman; Doug, Strother; Álmos, Klekner; László, Bognár; Garami, Miklós; Hauser, Péter; Hortobágyi, Tibor; Beverly, Wilson; Juliette, Hukin; Anne-Sophie, Carret; Timothy, E Van Meter; Eugene, I Hwang; Amar, Gajjar; Shih-Hwa, Chiou; Hideo, Nakamura; Helen, Toledano; Iris, Fried; Daniel, Fults; Takafumi, Wataya; Chris, Fryer; David, D Eisenstat; Katrin, Scheinemann; Adam, J Fleming; Donna, L Johnston; Jean, Michaud; Shayna, Zelcer; Robert, Hammond; Samina, Afzal; David, A Ramsay; Nongnuch, Sirachainan; Suradej, Hongeng; Noppadol, Larbcharoensub; Richard, G Grundy; Rishi, R Lulla; Jason, R Fangusaro; Harriet, Druker; Ute, Bartels; Ronald, Grant; David, Malkin; C Jane, McGlade; Theodore, Nicolaides; Tarik, Tihan; Joanna, Phillips; Jacek, Majewski; Alexandre, Montpetit; Guillaume, Bourque; Gary, D Bader; Alyssa, T Reddy; G Yancey, Gillespie; Monika, Warmuth-Metz; Stefan, Rutkowski; Uri, Tabori; Mathieu, Lupien; Michael, Brudno; Ulrich, Sch€uller; Torsten, Pietsch; Alexander, R Judkins; Cynthia, E Hawkins; Eric, Bouffet; Seung-Ki, Kim; Peter, B Dirks; Michael, D Taylor; Anat, Erdreich-Epstein; Cheryl, H Arrowsmith; Daniel, D De Carvalho; James, T Rutka; Nada, Jabado; Annie, Huang (2016)
    We recently reported that atypical teratoid rhabdoid tumors (ATRTs) comprise at least two transcriptional subtypes with different clinical outcomes; however, the mechanisms underlying therapeutic heterogeneity remained ...
  • Integrated genomic analysis identifies recurrent mutations and evolution patterns driving the initiation and progression of follicular lymphoma 
    Okosun J; Bödör, Csaba; Wang J; Araf S; Yang C-Y; Pan C; Boller S; Cittaro D; Bozek M; Iqbal S; Matthews J; Wrench D; Marzec J; Tawana K; Popov N; O'Riain C; O'Shea D; Carlotti E; Davies A; Lawrie CH; Matolcsy, András; Calaminici M; Norton A; Byers RJ; Mein C; Stupka E; Lister TA; Lenz G; Montoto S; Gribben JG; Fan Y; Grosschedl R; Chelala C; Fitzgibbon J (2014)
    Follicular lymphoma is an incurable malignancy, with transformation to an aggressive subtype representing a critical event during disease progression. Here we performed whole-genome or whole-exome sequencing on 10 follicular ...
  • Integrated MicroRNA-mRNA Profiling Identifies Oncostatin M as a Marker of Mesenchymal-Like ER-Negative/HER2-Negative Breast Cancer 
    Bottai G; Diao L; Baggerly KA; Paladini L; Győrffy, Balázs; Raschioni C; Pusztai L; Calin GA; Santarpia L (2017)
    MicroRNAs (miRNAs) simultaneously modulate different oncogenic networks, establishing a dynamic system of gene expression and pathway regulation. In this study, we analyzed global miRNA and messenger RNA (mRNA) expression ...
  • Integrated molecular analysis of Tamoxifen-resistant invasive lobular breast cancer cells identifies MAPK and GRM/mGluR signaling as therapeutic vulnerabilities 
    Stires H; Heckler MM; Fu X; Li Z; Grasso CS; Quist MJ; Lewis JA; Klimach U; Zwart A; Mahajan A; Győrffy, Balázs; Cavalli LR; Riggins RB (2018)
    Invasive lobular breast cancer (ILC) is an understudied malignancy with distinct clinical, pathological, and molecular features that distinguish it from the more common invasive ductal carcinoma (IDC). Mounting evidence ...
  • Integrated Systems Biology Approach Identifies Novel Maternal and Placental Pathways of Preeclampsia 
    Nandor Gabor Than; Roberto Romero; Adi Laurentiu Tarca; Kékesi Adrienna Katalin; Yi Xu; Zhonghui Xu; Kata Juhasz; Gaurav Bhatti; Ron Joshua Levitt; Zsolt Gelencser; Janos Palhalmi; Tzu Hung Chung; Balazs Andras Gyorffy; Laszlo Orosz; Demeter Amanda; Anett Szecsi; Hunyadi-Gulyás Éva Csilla; Darula Zsuzsanna; Simor Attila; Katalin Eder; Csörgőné Szabó Szilvia; Vanessa Topping; Haidy El-Azzamy; Christopher LaJeunesse; Andrea Balogh; Gabor Szalai; Susan Land; Olga Torok; Zhong Dong; Kovalszky Ilona; Falus András; Hamutal Meiri; Sorin Draghic; Sonia S Hassan; Tinnakorn Chaiworapongsa; Manuel Krispin; Martin Knöfler; Offer Erez; Graham J Burton; Chong Jai Kim; Juhász Gábor Dénes; Papp Zoltán (2018)
  • Integrative Bioinformatics Analysis Reveals New Prognostic Biomarkers of Clear Cell Renal Cell Carcinoma 
    Butz, Henriett; Szabo PM,; Nofech-Mozes R,; Rotondo F,; Kovacs K,; Patócs, Attila Balázs (2014)
    BACKGROUND: The outcome of clear cell renal cell carcinoma (ccRCC) is still unpredictable. Even with new targeted therapies, the average progression-free survival is dismal. Markers for early detection and progression could ...
  • Integrative characterization of chronic cigarette smoke-induced cardiopulmonary comorbidities in a mouse model 
    Kemény, Ágnes; Csekő, Kata; Szitter, István; Varga, Zoltán; Bencsik, Péter; Kiss, Krisztina; Halmosi, Róbert; Deres, László; Erős, Krisztián; Perkecz A; Kereskai, László; Horváthné László, Terézia; Kiss T; Ferdinandy, Péter; Helyes, Zsuzsanna (2017)
    Cigarette smoke-triggered inflammatory cascades and consequent tissue damage are the main causes of chronic obstructive pulmonary disease (COPD). There is no effective therapy and the key mediators of COPD are not identified ...
  • Intelligens telediabetológiai rendszer fejlesztése 
    Dió, Mihály (2017)
  • Intensive chemotherapy for childhood acute lymphoblastic leukemia: results of the randomized intercontinental trial ALL IC-BFM 2002 
    Stary Jan; Zimmermann Martin; Campbell Myriam; Castillo Luis; Dibar Eduardo; Svetlana Donska; Alejandro Gonzalez; Shai Izraeli; Dragana Janic; Janez Jazbec; Josip Konja; Emilia Kaiserova; Jerzy Kowalczyk; Kovács, Gábor; Chi-Kong Li; Edina Magyarosy; Alexander Popa; Batia Stark; Yahia Jabali; Jan Trka; Ondrej Hrusak; Hansjörg Riehm; Giuseppe Masera; Martin Schrappe (2014)
    PURPOSE: From 2002 to 2007, the International Berlin-Frankfurt-Munster Study Group conducted a prospective randomized clinical trial (ALL IC-BFM 2002) for the management of childhood acute lymphoblastic leukemia (ALL) in ...
  • Interaction between Angiotensin-converting enzyme gene insertion/deletion polymorphism and Angiotensin-converting enzyme inhibition on survival in hemodialyzed patients. 
    Kiss, István; Ambrus, Csaba; Kulcsar I; Szegedi J; Kerkovits, Lóránt Péter; Tislér, András; Kiss, Zoltán; BBAVHU-DIALGENE Workgroup (2014)
    The association between ACE (angiotensin-converting enzyme) gene insertion/deletion (I/D) polymorphism and mortality has been inconsistently observed in earlier studies in patients on maintenance hemodialysis. We hypothesized ...
  • Interaction between Connexin 43 and nitric oxide synthase in mice heart mitochondria 
    Kirca M; Kleinbongard P; Soetkamp D; Heger J; Csonka, Csaba; Ferdinandy, Péter; Schulz R (2015)
    Connexin 43 (Cx43), which is highly expressed in the heart and especially in cardiomyocytes, interferes with the expression of nitric oxide synthase (NOS) isoforms. Conversely, Cx43 gene expression is down-regulated by ...