tallózása szerző szerint "Antal, Péter"

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Beyond Structural Equation Modeling: model properties and effect size from a Bayesian viewpoint. An example of complex phenotype - genotype associations in depression.

Hullám, Gábor István; Juhász, Gabriella; Bagdy, György; Antal, Péter (2012)

Despite the rapid evolution of measurement technologies in biomedicine and genetics, most of the recent studies aiming to explore the genetic background of multifactorial diseases were only moderately successful. One ...
Candidate gene association study in pediatric acute lymphoblastic leukemia evaluated by Bayesian network based Bayesian multilevel analysis of relevance

Lautner-Csorba, Orsolya; Gézsi, András; Semsei, Ágnes F; Antal, Péter; Erdélyi, Dániel; Schermann G; Kutszegi, Nóra; Csordas, Katalin; Hegyi, Márta; Kovács, Gábor; Falus, András; Szalai, Csaba (2012)

Background: We carried out a candidate gene association study in pediatric acute lymphoblastic leukemia (ALL) to identify possible genetic risk factors in a Hungarian population. Methods: The results were evaluated with ...
Comorbidities in the diseasome are more apparent than real: What Bayesian filtering reveals about the comorbidities of depression

Marx, Péter; Antal, Péter; Bolgár, Bence Márton; Bagdy, György; Deakin B; Juhász, Gabriella (2017)

Comorbidity patterns have become a major source of information to explore shared mechanisms of pathogenesis between disorders. In hypothesis-free exploration of comorbid conditions, disease-disease networks are usually ...
Complex analysis of multiple single nucleotide polymorphisms as putative risk factors of tooth agenesis in the Hungarian population

Óvári, Gabriella; Páska, Csilla; Stiedl, Péter; Trimmel, Bálint; Dorina Hontvári; Soós, Borbála; Hermann, Péter; Tóth, Zsuzsanna; Bernadette Kerekes-Máthé; Dávid Nagy; Szántó, Ildikó; Nagy, Ákos; Mihály Martonosi; Nagy, Katalin; Éva Hadadi; Szalai, Csaba; Hullám, Gábor István; Temesi, Gergely; Antal, Péter; Varga, Gábor; Tarján, Ildikó (2014)
Evaluation of a Partial Genome Screening of Two Asthma Susceptibility Regions Using Bayesian Network Based Bayesian Multilevel Analysis of Relevance

Ungvári, Ildikó; Hullám, Gábor; Antal, Péter; Kiszel, Petra Sz; Gézsi, András; Hadadi, Éva; Virág, Viktor; Hajós, Gergely; Millinghoffer, András; Nagy, Adrienne; Kiss, András; Semsei, Ágnes F; Temesi, Gergely; Melegh, Béla; Kisfali, Péter; Széll, Márta; Bikov, András; Gálffy, Gabriella; Tamási, Lilla; Falus, András; Szalai, Csaba (2012)

Genetic studies indicate high number of potential factors related to asthma. Based on earlier linkage analyses we selected the 11q13 and 14q22 asthma susceptibility regions, for which we designed a partial genome screening ...
From genomes to diaries: a 3-year prospective, real-life study of ragweed-specific sublingual immunotherapy

Molnár, Viktor; Nagy, Arienne; Tamási, Lilla; Gálffy, Gabriella; Böcskei, Renáta; Bikov, András; Czaller, Ibolya; Csoma, Zoltán; Krasznai, Magdolna; Csaki, C; Zsigmond, G; Csontos, Z; Kurucz, A; Kurucz, E; Fábos, Beáta; Bálint, Bálint László; Sasvári-Székely, Mária; Székely, Aanna; Kotyuk, Eszter; Kozma, Gergely Tibor; Cserta, G; Farkas, A; Gá, Zsófia; Gézsi, András; Millinghoffer, A; Antal, Péter; Szalai, Csaba (2017)

During the last decades, the prevalence of allergy has dramatically increased. Allergen-specific immunotherapy is the only currently available medical intervention that has the potential to affect the natural course of the ...
Genetic variants in major depressive disorder: From pathophysiology to therapy

Gonda, Xénia; Petschner, Péter; Eszlári, Nóra; Baksa, Dániel; Édes, Andrea Edit; Antal, Péter; Juhász, Gabriella; Bagdy, György (2019)

In spite of promising preclinical results there is a decreasing number of new registered medications in major depression. The main reason behind this fact is the lack of confirmation in clinical studies for the assumed, ...
Genome-wide association analysis reveals KCTD12 and miR-383-binding genes in the background of rumination

Eszlári, Nóra; Millinghoffer, András Dániel; Petschner, Péter; Gonda, Xénia; Baksa, Dániel; Pulay, Attila József; Réthelyi, János; Breen Gerome; Deakin John Francis William; Antal, Péter; Bagdy, György; Juhász, Gabriella (2019)

Ruminative response style is a passive and repetitive way of responding to stress, associated with several disorders. Although twin and candidate gene studies have proven the genetic underpinnings of rumination, no genome-wide ...
In interaction with gender a common CYP3A4 polymorphism may influence the survival rate of chemotherapy for childhood acute lymphoblastic leukemia

Gézsi, András; Lautner-Csorba, Orsolya; Erdélyi, Dániel; Hullám, Gábor István; Antal, Péter; Semsei, Ágnes F; Kutszegi, Nóra; Hegyi, Márta; Csordas, Katalin; Kovács, Gábor; Szalai, Csaba (2015)

CYP3A4 has an important role in the metabolisms of many drugs used in acute lymphoblastic leukemia (ALL) therapy; still, there are practically no publications about the role of CYP3A4 polymorphisms in ALL pharmacogenomics. ...
Investigation of the Possible Role of the Hippo/YAP1 Pathway in Asthma and Allergy

Fodor, Lili Erika; Gézsi, András; Ungvári, Ildikó; Semsei, Ágnes F; Gál, Zsófia; Nagy, A; Gálffy, Gabriella; Tamási, Lilla; Kiss, András Pál; Antal, Péter; Szalai, Csaba (2017)

PURPOSE: Several lines of evidence indicate that the Hippo/Yes-associated protein 1 (YAP1) pathways might play a role in the pathogenesis of asthma. To investigate the possible role of the Hippo/YAP1 pathway in the ...
Multivariate Analysis of Dopaminergic Gene Variants as Risk Factors of Heroin Dependence

Vereczkei, Andrea; Demetrovics, Zsolt; Székely, Anna; Sárközy, Péter; Antal, Péter; Szilágyi, Ágnes; Sasvári-Székely, Mária; Barta, Csaba (2013)
Non-synonymous single nucleotide polymorphisms in genes for immunoregulatory galectins: Association of galectin-8 (F19Y) occurrence with autoimmune diseases in a Caucasian population

Pál, Zsuzsanna; Antal, Péter; Srivastava SK; Hullám, Gábor István; Semsei, Ágnes F; Gál J; Svébis M; Soós G; Szalai, Csaba; André S; Gordeeva E; Nagy, György; Kaltner H; Bovin NV; Molnár, Mária Judit; Falus, András; Gabius HJ; Buzás, Edit Irén (2012)
Novel genes in Human Asthma Based on a Mouse Model of Allergic Airway Inflammation and Human Investigations

Temesi, Gergely; Virág, V; Hadadi, É; Ungvári, Ildikó; Fodor, Lili Erika; Bikov, András; Nagy, A; Gálffy, Gabriella; Tamási, Lilla; Horváth, Ildikó; Kiss, András Pál; Hullám, Gábor István; Gézsi, András; Sárközy, Péter; Antal, Péter; Buzás, Edit Irén; Szalai, Csaba (2014)
Pharmacogenetic analysis of high-dose methotrexate treatment in children with osteosarcoma.

Hegyi, Márta; Arany, Ádám; Semsei, Ágnes F; Csordas, Katalin; Eipel, Olivér; Gézsi, András; Kutszegi, Nóra; Csóka, Monika; Müller, Judit; Erdélyi, Dániel; Antal, Péter; Szalai, Csaba; Kovács, Gábor (2017)

Inter-individual differences in toxic symptoms and pharmacokinetics of high-dose methotrexate (MTX) treatment may be caused by genetic variants in the MTX pathway. Correlations between polymorphisms and pharmacokinetic ...
Variability in the Effect of 5-HTTLPR on Depression in a Large European Population: The Role of Age, Symptom Profile, Type and Intensity of Life Stressors.

Juhász, Gabriella; Gonda, Xénia; Hullám, Gábor; Eszlári, Nóra; Kovács, Dávid; Lazáry, Judit; Pap, Dorottya; Petschner, Péter; Elliott R; Deakin JF; Anderson IM; Antal, Péter; Lesch KP; Bagdy, György (2015)

BACKGROUND: Although 5-HTTLPR has been shown to influence the risk of life stress-induced depression in the majority of studies, others have produced contradictory results, possibly due to weak effects and/or sample ...
VariantMetaCaller: automated fusion of variant calling pipelines for quantitative, precision-based filtering

Gézsi, András; Bolgár, Bence Márton; Marx, Péter; Sárközy, Péter; Szalai, Csaba; Antal, Péter (2015)

BACKGROUND: The low concordance between different variant calling methods still poses a challenge for the wide-spread application of next-generation sequencing in research and clinical practice. A wide range of variant ...

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