tallózása szerző szerint "Bünger R"

1-3 / 3

A porcine model of complement-mediated infusion reactions to drug carrier nanosystems and other medicines

Szebeni, János; Bedőcs, Péter; Csukás, Domokos; Rosivall, László; Bünger R; Urbanics R (2012)

Intravenous administration of low (milligram) doses of nanoparticulate materials in pigs can lead to acute cardiopulmonary, hemodynamic, hematological, biochemical and dermatological changes within minutes, mimicking the ...
Liposome-induced complement activation and related cardiopulmonary distress in pigs: factors promoting reactogenicity of Doxil and AmBisome

Szebeni, János; Bedőcs, Péter; Rozsnyay Z; Weiszhar, Zsóka; Urbanics R; Rosivall, László; Cohen R; Garbuzenko O; Báthori G; Tóth, Miklós; Bünger R; Barenholz Y (2012)

Hypersensitivity reactions to liposomal drugs, often observed with Doxil and AmBisome, can arise from activation of the complement (C) system by phospholipid bilayers. To understand the mechanism of this adverse immune ...
Prevention of infusion reactions to PEGylated liposomal doxorubicin via tachyphylaxis induction by placebo vesicles: A porcine model

Szebeni, János; Bedőcs, Péter; Urbanics R; Bünger R; Rosivall, László; Tóth, Miklós; Barenholz Y (2012)

PEGylated liposomal doxorubicin (Doxil) has been used in cancer chemotherapy for 16 years. Clinical experience shows that it can cause mild-to-severe hypersensitivity (infusion) reactions, which are manifestations of ...

1-3 / 3

Keresés