tallózása szerző szerint "Csabai, István"

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  • Aberrant DNA methylation of WNT pathway genes in the development and progression of CIMP-negative colorectal cancer 
    Udvardyné Galamb, Orsolya; Kalmár, Alexandra; Péterfia, Bálint; Csabai, István; Bodor, András; Ribli, Dezső; Krenács, Tibor; Patai, Árpád V; Wichmann, Barnabás; Barták, Barbara Kinga; Tóth, Kinga; Valcz, Gábor; Tulassay, Zsolt; Molnár, Béla (2016)
    The WNT signaling pathway has an essential role in colorectal carcinogenesis and progression, which involves a cascade of genetic and epigenetic changes. We aimed to analyze DNA methylation affecting the WNT pathway genes ...
  • A comprehensive survey of the mutagenic impact of common cancer cytotoxics 
    Szikriszt, Bernadett; Póti, Ádám; Pipek, Orsolya; Krzystanek, Marcin; Kanu, Nnennaya; Molnár, János; Ribli, Dezső; Szeltner, Zoltán; Tusnády, Gábor; Csabai, István; Szállási, Zoltán; Charles, Swanton; Szüts, Dávid (2016)
  • A novel genomic alteration of LSAMP associates with aggressive prostate cancer in African American men 
    Petrovics Gyorgy; Li Hua; Stuempel Tanja; Tan Shyh-Han; Young Denise; Katta Shilpa; Li Qiyuan; Ying Kai; Klocke Bernward; Ravindranath Lakshmi; Kohaar Indu; Chen Yongmei; Ribli Dezso; Grote Korbinian; Zou Hua; Cheng Joseph; Dalgard Clifton L; Zhang Shimin; Csabai, István; Kagan Jacob; Takeda David; Loda Massimo; Srivastava Sudhir; Scherf Matthias; Seifert Martin; Gaiser Timo; McLeod David G; Szállási, Zoltán; Ebner Reinhard; Werner Thomas; Sesterhenn Isabell A; Freedman Matthew; Dobi Albert; Srivastava Shiv (2015)
    Evaluation of cancer genomes in global context is of great interest in light of changing ethnic distribution of the world population. We focused our study on men of African ancestry because of their disproportionately ...
  • CAUSEL: an epigenome- and genome-editing pipeline for establishing function of noncoding GWAS variants 
    Spisák, Sándor; Kate Lawrenson; Yanfang Fu; Csabai, István; Rebecca T Cottman; Christopher Haiman; Ying Han; Ji-Heui Seo; Romina Lenci; Qiyuan Li; Viktória Tisza; Szállási, Zoltán; Zachery T. Herbert; Matthew Chabo; Mark Pomerantz; Norbert, Solymosi; Simon Gaythe; J. Keith Joung; Matthew L. Freedman (2015)
  • Complete genes may pass from food to human blood 
    Spisák, Sándor; Solymosi, Norbert; Ittzés, Péter; Bodor, András; Kondor, Dániel; Vattay, Gábor; Barták, Barbara Kinga; Sipos, Ferenc; Udvardyné Galamb, Orsolya; Tulassay, Zsolt; Szállási Zoltán; Rasmussen Simon; Sicheritz-Ponten Thomas; Brunak Sören; Molnár, Béla; Csabai, István (2013)
  • Fast and accurate mutation detection in whole genome sequences of multiple isogenic samples with IsoMut 
    Pipek, Orsolya Anna; Ribli, Dezső; Molnár, János; Póti Á; Krzystanek M; Bodor, András; Tusnády, Gábor; Szállási, Zoltán; Csabai, István; Szüts, Dávid (2017)
    Background: Detection of somatic mutations is one of the main goals of next generation DNA sequencing. A wide range of experimental systems are available for the study of spontaneous or environmentally induced mutagenic ...
  • Loss of BRCA1 or BRCA2 markedly increases the rate of base substitution mutagenesis and has distinct effects on genomic deletions 
    Zámborszky, Judit; Szikriszt, Bernadett; Gervai, Judit Zsuzsanna; Pipek, Orsolya Anna; Póti Á; Krzystanek M; Ribli, Dezső; Szalai-Gindl, János Márk; Csabai, István; Szállási, Zoltán; Swanton C; Richardson AL; Szüts, Dávid (2017)
    Loss-of-function mutations in the BRCA1 and BRCA2 genes increase the risk of cancer. Owing to their function in homologous recombination repair, much research has focused on the unstable genomic phenotype of BRCA1/2 mutant ...
  • Migrating the SNP array-based homologous recombination deficiency measures to next generation sequencing data of breast cancer 
    Sztupinszki Zsofia; Diossy Miklos; Krzystanek Marcin; Reiniger, Lilla; Csabai, István; Favero Francesco; Birkbak Nicolai J; Eklund Aron C; Syed Ali; Szállási, Zoltán (2018)
    The first genomic scar-based homologous recombination deficiency (HRD) measures were produced using SNP arrays. As array-based technology has been largely replaced by next generation sequencing approaches, it has become ...