tallózása szerző szerint "Hamar, Péter"

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Activation of the miR-17 Family and miR-21 During Murine Kidney Ischemia-Reperfusion Injury.

Kaucsár, Tamás; Revesz C; Godo M; Krenács, Tibor; Albert M; Szalay, Csaba Imre; Rosivall, László; Benyó, Zoltán; Batkai S; Thum T; Szénási, Gábor; Hamar, Péter (2013)

Background: Ischemia-reperfusion (I/R) is the main cause of acute kidney injury (AKI) in patients. We investigated renal microRNA (miRNA) expression profiles and the time course of changes in selected miRNA expressions ...
Alterations in SCAI Expression during Cell Plasticity, Fibrosis and Cancer

Gasparics, Ákos; Kökény, Gábor; Fintha, Attila; Bencs R; Mózes, Miklós; Ágoston EI; Buday, Anna; Ivics, Zoltán; Hamar, Péter; Győrffy, Balázs; Rosivall, László; Sebe, Attila (2018)
Association of CTLA-4 Polymorphisms with Type 1 Diabetes in the Egyptian Population

Hatem Mohamed Saleh,; Bobby Koeleman,; Szénási, Gábor; Rosivall, László; Hamar, Péter (2013)
Characterization and Role of SCAI during Renal Fibrosis and Epithelial-Mesenchymal Transition.

Fintha, Attila; Gasparics, Ákos; Fang, Lilla; Erdei, Zsuzsa; Hamar, Péter; Mózes, Miklós; Kökény, Gábor; Rosivall, László; Sebe, Attila (2013)

During progressive tubulointerstitial fibrosis, renal tubular epithelial cells transform into alpha-smooth muscle actin (SMA)- expressing myofibroblasts via epithelial-mesenchymal transition (EMT). SMA expression is ...
Diastolic dysfunction in prediabetic male rats: role of mitochondrial oxidative stress

Koncsos, Gábor; Varga, Zoltán; Baranyai, Tamás; Boengler K; Rohrbach S; Li L; Schluter KD; Schreckenberg R; Radovits, Tamás; Oláh, Attila; Mátyás, Csaba; Lux, Árpád; Al-Khrasani, Mahmoud; Komlódi, Tímea; Bukosza, Éva Nóra; Máthé, Domokos; Deres, László; Bartekova M; Rajtik T; Adameova A; Szigeti, Krisztián; Hamar, Péter; Helyes, Zsuzsanna; Tretter, László; Pacher, Pál; Merkely, Béla Péter; Giricz, Zoltán; Schulz R; Ferdinandy, Péter (2016)

Although incidence and prevalence of prediabetes are increasing, little is known on its cardiac effects. Therefore, our aim was to investigate the effect of prediabetes on cardiac function and to characterize parameters ...
Effects of vitamin D3 derivate calcitriol on pharmacological reactivity of aortic rings in a rodent PCOS model

Masszi, Gabriella; Novák, Ágnes; Tarszabó, Róbert; Horváth, Eszter Mária; Buday, Anna; Ruisanchez, Éva; Tőkés, Anna-Mária; Sára, Levente; Benkő, Rita; Nádasy, György László; Révész, Csaba; Hamar, Péter; Benyó, Zoltán; Várbíró, Szabolcs (2013)

BACKGROUND: The aim of this study was to examine the effects of the hyperandrogenic state in dihydrotestosterone (DHT)-induced polycystic ovary syndrome (PCOS), the vascular responses to different vasoactive agents, and ...
Endothelial relaxation mechanisms and nitrative stress are partly restored by Vitamin D3 therapy in a rat model of polycystic ovary syndrome

Masszi G; Benkő, Rita; Csibi N; Horvath, Eszter Mária; Tőkés, Anna-Mária; Novak A; Béres, Nóra; Tarszabó, Róbert; Buday, Anna; Repas Cs; Békési, Gábor; Patócs, Attila Balázs; Nádasy, György László; Hamar, Péter; Benyó, Zoltán; Várbíró, Szabolcs (2013)

AIMS: In polycystic ovary syndrome (PCOS), metabolic and cardiovascular dysfunction is related to hyperandrogenic status and insulin resistance, however, Vitamin D3 has a beneficial effect partly due to its anti-oxidant ...
Ezrin is down-regulated in diabetic kidney glomeruli and regulates actin reorganization and glucose uptake via GLUT1 in cultured podocytes

Wasik AA; Koskelainen S; Hyvönen ME; Musante L; Lehtonen E; Koskenniemi K; Tienari J; Vaheri A; Kerjaschki D; Szalay, Csaba Imre; Révész C; Varmanen P; Nyman TA; Hamar, Péter; Holthöfer H; Lehtonen S (2014)

Diabetic nephropathy is a complication of diabetes and a major cause of end-stage renal disease. To characterize the early pathophysiological mechanisms leading to glomerular podocyte injury in diabetic nephropathy, we ...
Fitness cost associated with resistance to fluoroquinolones is diverse across clones of Klebsiella pneumoniae and may select for CTX-M-15 type extended-spectrum β -lactamase

Tóth, Ákos; Kocsis, Béla; Damjanova, I; Kristóf, Katalin; Jánvári, L; Pászti, J; Csercsik, Rita; Topf, J; Szabó, Dóra; Hamar, Péter; Nagy, Károly; Füzi, Miklós (2014)
Glomerular Collagen Deposition and Lipocalin-2 Expression Are Early Signs of Renal Injury in Prediabetic Obese Rats

Bukosza, Eva Nora; Kaucsár, Tamás; Godó, Mária; Lajtár, Enikő; Tod, Pál; Koncsos, Gábor; Varga, Zoltán V; Baranyai, Tamás; Tu, Nguyen Minh; Schachner, Helga; Sőti, Csaba; Ferdinandy, Péter; Giricz, Zoltán; Szénási, Gábor; Hamar, Péter (2019)

Feeding rats with high-fat diet (HFD) with a single streptozotocin (STZ) injection induced obesity, slightly elevated fasting blood glucose and impaired glucose and insulin tolerance, and caused cardiac hypertrophy and ...
Oxidative/Nitrative Stress and Inflammation Drive Progression of Doxorubicin-Induced Renal Fibrosis in Rats as Revealed by Comparing a Normal and a Fibrosis-Resistant Rat Strain

Szalay, Csaba Imre; Erdélyi, Katalin; Kökény, Gábor; Lajtar E; Godo M; Revesz C; Kaucsár, Tamás; Kiss, Norbert; Sárközy, Márta; Csont, Tamás Bálint; Krenács, Tibor; Szénási, Gábor; Pacher, Pál; Hamar, Péter (2015)

Chronic renal fibrosis is the final common pathway of end stage renal disease caused by glomerular or tubular pathologies. Genetic background has a strong influence on the progression of chronic renal fibrosis. We recently ...
Post-Ischemic Renal Fibrosis Progression Is Halted by Delayed Contralateral Nephrectomy : The Involvement of Macrophage Activation

Tod, Pál; Bukosza, Eva Nora; Róka, Beáta; Kaucsár, Tamás; Fintha, Attila; Krenács, Tibor; Szénási, Gábor; Hamar, Péter (2020)

(1) Background: Successful treatment of acute kidney injury (AKI)-induced chronic kidney disease (CKD) is unresolved. We aimed to characterize the time-course of changes after contralateral nephrectomy (Nx) in a model of ...
Protective effect of CV247 against cisplatin nephrotoxicity in rats

Máthé, Csaba; Szénási, Gábor; Sebestény, A; Blázovics, Anna; Szentmihályi, Klára; Hamar, Péter; Albert, M (2014)

Abstract CV247 (CV), an aqueous mixture of copper (Cu) and manganese (Mn) gluconates, vitamin C and sodium salicylate increased the antitumour effects of cisplatin (CDPP; cis-diamminedichloroplatinum) in vitro. We ...
Rodent models of complement activation-related pseudoallergy: Inducers, symptoms, inhibitors and reaction mechanisms

Dézsi, László; Rosivall, László; Hamar, Péter; Szebeni, János; Szénási, Gábor (2015)

Complement activation-related pseudoallergy (CARPA) is a hypersensitivity reaction to intravenous administration of nanoparticle-containing medicines (nanomedicines). This review focuses on CARPA in rodent models: rats, ...
Selegiline reduces adiposity induced by high-fat, high-sucrose diet in male rats

Nagy CT; Koncsos, Gábor; Varga, Zoltán; Baranyai T; Tuza S; Kassai F; Ernyey AJ; Gyertyan I; Kiraly K; Oláh, Attila; Radovits, Tamás; Merkely, Béla Péter; Bukosza N; Szénási, Gábor; Hamar, Péter; Mathe D; Szigeti K; Pelyhe C; Jelemensky M; Onodi Z; Helyes, Zsuzsanna; Schulz R; Giricz, Zoltán; Ferdinandy, Péter (2018)

BACKGROUND AND PURPOSE: Incidence and severity of obesity is increasing worldwide. To date, efficient and safe pharmacological tools to treat or prevent obesity have not been developed. Certain monoamine-oxidase (MAO) ...
Sigma1-Receptor Agonism Protects against Renal Ischemia-Reperfusion Injury

Hosszú, Ádám; Antal, Zsuzsanna; Lénárt, Lilla; Hodrea, Judit; Kőszegi, Sándor; Balogh, Dóra Bianka; Bánki, Nóra Fanni; Wágner, László József; Dénes, Ádám; Hamar, Péter; Degrell P; Vannay, Ádám; Szabó, Attila; Fekete, Andrea (2017)

Mechanisms of renal ischemia-reperfusion injury remain unresolved, and effective therapies are lacking. We previously showed that dehydroepiandrosterone protects against renal ischemia-reperfusion injury in male rats. ...
The Acute Phase Response Is a Prominent Renal Proteome Change in Sepsis in Mice

Róka, Beáta; Tod, Pál; Kaucsár, Tamás; Vizovišek, Matej; Vidmar, Robert; Turk, Boris; Fonović, Marko; Szénási, Gábor; Hamar, Péter (2020)
Urine/Plasma Neutrophil Gelatinase Associated Lipocalin Ratio Is a Sensitive and Specific Marker of Subclinical Acute Kidney Injury in Mice

Kaucsár, Tamás; Godo M; Revesz C; Kovács, Miklós; Mócsai, Attila; Albert M; Krenacs T; Kiss, Norbert; Szénási, Gábor; Hamar, Péter (2016)

Background Detection of acute kidney injury (AKI) is still a challenge if conventional markers of kidney function are within reference range. We studied the sensitivity and specificity of NGAL as an AKI marker at different ...

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