tallózása szerző szerint "Helyes, Zsuzsanna"

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Capsaicin-sensitive sensory nerves exert complex regulatory functions in the serum-transfer mouse model of autoimmune arthritis

Borbély, Éva; Botz, Bálint; Bölcskei, Kata; Kenyer T; Kereskai, László; Kiss T; Szolcsányi, János; Pintér, Erika; Csepregi, Janka Zsófia; Mócsai, Attila; Helyes, Zsuzsanna (2015)

OBJECTIVE: The K/BxN serum-transfer arthritis is a widely-used translational mouse model of rheumatoid arthritis, in which the immunological components have thoroughly been investigated. In contrast, little is known about ...
Diastolic dysfunction in prediabetic male rats: role of mitochondrial oxidative stress

Koncsos, Gábor; Varga, Zoltán; Baranyai, Tamás; Boengler K; Rohrbach S; Li L; Schluter KD; Schreckenberg R; Radovits, Tamás; Oláh, Attila; Mátyás, Csaba; Lux, Árpád; Al-Khrasani, Mahmoud; Komlódi, Tímea; Bukosza, Éva Nóra; Máthé, Domokos; Deres, László; Bartekova M; Rajtik T; Adameova A; Szigeti, Krisztián; Hamar, Péter; Helyes, Zsuzsanna; Tretter, László; Pacher, Pál; Merkely, Béla Péter; Giricz, Zoltán; Schulz R; Ferdinandy, Péter (2016)

Although incidence and prevalence of prediabetes are increasing, little is known on its cardiac effects. Therefore, our aim was to investigate the effect of prediabetes on cardiac function and to characterize parameters ...
Differential Regulatory Role of Pituitary Adenylate Cyclase–Activating Polypeptide in the Serum-Transfer Arthritis Model

Botz, Bálint; Bölcskei, Kata; Kereskai, László; Kovács, Miklós; Németh, Tamás; Szigeti, Krisztián; Horváth I; Máthé, Domokos; Kovács N; Hashimoto H; Reglődi, Dóra; Szolcsányi, János; Pintér, Erika; Mócsai, Attila; Helyes, Zsuzsanna (2014)

OBJECTIVE: Pituitary adenylate cyclase-activating polypeptide (PACAP) expressed in capsaicin-sensitive sensory neurons and immune cells has divergent functions in inflammatory and pain processes. This study was undertaken ...
Glial cell type-specific changes in spinal dipeptidyl peptidase 4 expression and effects of its inhibitors in inflammatory and neuropatic pain

Király, Kornél P; Kozsurek, Márk; Lukacsi E; Barta B; Alpár, Alán; Balázsa, Tamás; Fekete, Csaba; Szabon J; Helyes, Zsuzsanna; Bölcskei, Kata; Tékus, Valéria; Tóth, Zsuzsanna; Pap, Károly; Gerber, Gábor; Puskár, Zita (2018)

Altered pain sensations such as hyperalgesia and allodynia are characteristic features of various pain states, and remain difficult to treat. We have shown previously that spinal application of dipeptidyl peptidase 4 (DPP4) ...
Hydrophobic cyanine dye-doped micelles for optical in vivo imaging of plasma leakage and vascular disruption.

Botz, Bálint; Bölcskei, Kata; Kemény, Ágnes; Sándor, Zoltán; Tékus, Valéria; Sétáló, György (ifj.); Mócsai, Attila; Pintér, Erika; Kollár, László; Helyes, Zsuzsanna (2015)
Inhibition of alpha2A-adrenoceptors ameliorates DSS-induced acute intestinal inflammation in mice

Zádori, Zoltán Sándor; Tóth, Viktória; Fehér, Ágnes; Al-Khrasani, Mahmoud; Puskár, Zita; Kozsurek, Márk; Timár, Júlia; Tábi, Tamás; Helyes, Zsuzsanna; Lutz, Hein; Peter, Holzer; Gyires, Klára (2016)

It has been hypothesized that alpha2-adrenoceptors (alpha2-ARs) may be involved in the pathomechanism of colitis, however, the results are conflicting since both aggravation and amelioration of colonic inflammation have ...
Integrative characterization of chronic cigarette smoke-induced cardiopulmonary comorbidities in a mouse model

Kemény, Ágnes; Csekő, Kata; Szitter, István; Varga, Zoltán; Bencsik, Péter; Kiss, Krisztina; Halmosi, Róbert; Deres, László; Erős, Krisztián; Perkecz A; Kereskai, László; Horváthné László, Terézia; Kiss T; Ferdinandy, Péter; Helyes, Zsuzsanna (2017)

Cigarette smoke-triggered inflammatory cascades and consequent tissue damage are the main causes of chronic obstructive pulmonary disease (COPD). There is no effective therapy and the key mediators of COPD are not identified ...
Lack of Galanin 3 Receptor Aggravates Murine Autoimmune Arthritis

Botz, Bálint; Kemény, Ágnes; Brunner SM; Locker F; Csepregi, Janka Zsófia; Mócsai, Attila; Pintér, Erika; McDougall JJ; Kofler B; Helyes, Zsuzsanna (2016)

Neurogenic inflammation mediated by peptidergic sensory nerves has a crucial impact on the pathogenesis of various joint diseases. Galanin is a regulatory sensory neuropeptide, which has been shown to attenuate neurogenic ...
Lack of Small Intestinal Dysbiosis Following Long-Term Selective Inhibition of Cyclooxygenase-2 by Rofecoxib in the Rat

Lázár, Bernadette; Brenner, Gábor; Makkos, András; Balogh, Mihály; László, Szilvia Bianka; Al-Khrasani, Mahmoud; Hutka, Barbara; Bató, Emese; Ostorházi, Eszter; Juhász, János; Kemény, Ágnes; Horváthné László, Terézia; Tiszlavicz, László; Bihari, Zoltán; Giricz, Zoltán; Szabó, Dóra; Helyes, Zsuzsanna; Ferdinandy, Péter; Gyires, Klára; Zádori, Zoltán S (2019)

Intestinal dysbiosis is linked to numerous gastrointestinal disorders, including inflammatory bowel diseases. It is a question of debate if coxibs, selective inhibitors of cyclooxygenase (COX)-2, cause dysbiosis. Therefore, ...
New morphine analogues produce peripheral antinociception within a certain dose range of their systemic administration

Lackó, Erzsébet; Riba, Pál; Giricz, Zoltán; Váradi, András; Cornic L; Balogh, Mihály; Király, Kornél P; Csekő, Kata; Hosztafi, Sándor; Zádori, Zoltán Sándor; Helyes, Zsuzsanna; Ferdinandy, Péter; Fürst, Zsuzsanna; Al-Khrasani, Mahmoud (2016)

Growing data support the peripheral opioid antinociceptive effect, particularly, in inflammatory pain models. Here, we examined the antinociceptive effects of the subcutaneously (s.c.) administered, recently synthesized ...
Phospholipase Cγ2 is essential for experimental models of epidermolysis bullosa acquisita

Szilveszter, Kata Petra; Vikár, Simon; Horváth, Ádám István; Helyes, Zsuzsanna; Sárdy, Miklós; Mócsai, Attila (2022)
Pinus sylvestris L. and Syzygium aromaticum (L.) Merr. & L. M. Perry Essential Oils Inhibit Endotoxin-Induced Airway Hyperreactivity despite Aggravated Inflammatory Mechanisms in Mice.

Csikós, Eszter; Csekő, Kata; Kemény, Ágnes; Draskóczi, Lilla; Kereskai, László; Kocsis, Béla; Böszörményi, Andrea; Helyes, Zsuzsanna; Horváth, Györgyi (2022)

Scots pine (SO) and clove (CO) essential oils (EOs) are commonly used by inhalation, and their main components are shown to reduce inflammatory mediator production. The aim of our research was to investigate the chemical ...
Selegiline reduces adiposity induced by high-fat, high-sucrose diet in male rats

Nagy CT; Koncsos, Gábor; Varga, Zoltán; Baranyai T; Tuza S; Kassai F; Ernyey AJ; Gyertyan I; Kiraly K; Oláh, Attila; Radovits, Tamás; Merkely, Béla Péter; Bukosza N; Szénási, Gábor; Hamar, Péter; Mathe D; Szigeti K; Pelyhe C; Jelemensky M; Onodi Z; Helyes, Zsuzsanna; Schulz R; Giricz, Zoltán; Ferdinandy, Péter (2018)

BACKGROUND AND PURPOSE: Incidence and severity of obesity is increasing worldwide. To date, efficient and safe pharmacological tools to treat or prevent obesity have not been developed. Certain monoamine-oxidase (MAO) ...
Significance of the Tks4 scaffold protein in bone tissue homeostasis

Vas, Virág; Kovács, Tamás; Körmendi, Szandra Katalin; Bródy, Andrea; Kudlik, Gyöngyi; Szeder, Bálint; Mező, Diána; Kállai, Dóra; Koprivanacz, Kitti; Merő, Balázs László; Dülk, Metta; Tóvári, József; Vajdovich, Péter; Şenel, Ş Neslihan; Özcan, Ilknur; Helyes, Zsuzsanna; Dobó-Nagy, Csaba; Buday, László (2019)

The main driver of osteoporosis is an imbalance between bone resorption and formation. The pathogenesis of osteoporosis has also been connected to genetic alterations in key osteogenic factors and dysfunction of bone marrow ...
Subantimicrobial Dose Doxycycline Worsens Chronic Arthritis-Induced Bone Microarchitectural Alterations in a Mouse Model: Role of Matrix Metalloproteinases?

Horvath, Adam; Botz, Balint; Kiss, Tamas; Cseko, Kata; Kiss, Ibolya; Felinger, Attila; Szabados, Tamara; Kenyeres, Eva; Bencsik, Peter; Mocsai, Attila; Ferdinandy, Peter; Helyes, Zsuzsanna (2019)

Background: Rheumatoid arthritis (RA) is a chronic inflammatory joint disease hallmarked by irreversible damage of cartilage and bone. Matrix metalloproteinases (MMPs) involved in connective tissue remodeling play an ...
The Src family kinases Hck, Fgr, and Lyn are critical for the generation of the in vivo inflammatory environment without a direct role in leukocyte recruitment.

Kovács, Miklós; Németh, Tamás; Jakus, Zoltán; Sitaru C; Simon, Edina; Futosi, Krisztina; Botz, Bálint; Helyes, Zsuzsanna; Lowell CA; Mócsai, Attila (2014)

Although Src family kinases participate in leukocyte function in vitro, such as integrin signal transduction, their role in inflammation in vivo is poorly understood. We show that Src family kinases play a critical role ...
TRPA1 Ion Channel Determines Beneficial and Detrimental Effects of GYY4137 in Murine Serum-Transfer Arthritis

Bátai, István Zoárd; Pápainé Sár, Cecília; Horváth, Ádám; Kemény, Ágnes; Sándor, Zoltán; Nemes, Balázs; Helyes, Zsuzsanna; Perkecz, Anikó; Mócsai, Attila; Pozsgai, Gábor; Pintér, Erika (2019)

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tallózása szerző szerint "Helyes, Zsuzsanna"

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