tallózása szerző szerint "MTA Szegedi Biológiai Kutatóközpont"

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Biochemical and pharmacological characterization of three opioid-nociceptin hybrid peptide ligands reveals substantially differing modes of their actions.

Erdei, Anna; Borbély, Adina; Magyar, Anna; Taricska, Nóra; Perczel, András; Zsíros, Ottó; Garab, Győző; Szűcs, Edina; Ötvös, Ferenc; Zádor, Ferenc; Balogh, Mihály; Al-Khrasani, Mahmoud; Benyhe, Sándor (2018)

In an attempt to design opioid-nociceptin hybrid peptides, three novel bivalent ligands, H-YGGFGGGRYYRIK-NH2, H-YGGFRYYRIK-NH2 and Ac-RYYRIKGGGYGGFL-OH were synthesized and studied by biochemical, pharmacological, biophysical ...
Biochemical and pharmacological investigation of novel nociceptin/OFQ analogues and N/OFQ-RYYRIK hybrid peptides

Erdei, Anna I; Borbély, Adina; Magyar, Anna; Szűcs, Edina; Ötvös, Ferenc; Gombos, Dávid; Al-Khrasani, Mahmoud; Stefanucci, Azzurra; Dimmito, Marilisa Pia; Luisi, Grazia; Mollica, Adriano; Benyhe, Sándor (2019)
Endothelial-Mesenchymal Transition of Brain Endothelial Cells: Possible Role during Metastatic Extravasation

Krizbai, István Adorján; Gasparics, Ákos; Nagyőszi, Péter; Fazakas, Csilla; Molnár, Judit; Wilhelm Imola, Mária; Bencs R; Rosivall, László; Sebe, Attila (2015)

Cancer progression towards metastasis follows a defined sequence of events described as the metastatic cascade. For extravasation and transendothelial migration metastatic cells interact first with endothelial cells. Yet ...
Expression of matrilin-2 in liver cirrhosis and hepatocellular carcinoma

Szabó E; Korpos, Éva; Batmunkh E; Lotz, Gábor; Holczbauer Á; Kovalszky, Ilona; Deák, Ferenc; Kiss, Ibolya; Schaff, Zsuzsa; Kiss, András (2008)
Galectin-1 is a local but not systemic immunomodulatory factor in mesenchymal stromal cells.

Fajka-Boja, Roberta; Suhajdáné Urbán, Veronika; Szebeni, Gábor; Czibula, Ágnes; Blaskó, Andrea; Kriston-Pál, Éva; Makra, Ildikó; Hornung, Ákos; Szabó, Enikő; Than, Nándor Gábor; Monostori, Éva (2016)

BACKGROUND AIMS: Mesenchymal stromal cells (MSCs) have powerful immunosuppressive activity. This function of MSCs is attributed to plethora of the expressed immunosuppressive factors, such as galectin-1 (Gal-1), a pleiotropic ...
Lack of Matrilin-2 Favors Liver Tumor Development via Erk1/2 and GSK-3 beta Pathways In Vivo

Fullár, Alexandra; Baghy, Kornélia; Deák, Ferenc; Péterfia, Bálint; Zsak Y; Tátrai, Péter; Schaff, Zsuzsa; Dudas J; Kiss, Ibolya; Kovalszky, Ilona (2014)

Matrilin-2 (Matn2) is a multidomain adaptor protein which plays a role in the assembly of extracellular matrix (ECM). It is produced by oval cells during stem cell-driven liver regeneration. In our study, the impact of ...
Lessons from the canine Oxtr gene: populations, variants and functional aspects.

Bence Melinda; Peter Marx; Szántai Eszter; Kubinyi Enikő; Rónai Zsolt; Bánlaki Zsófia (2017)

Oxytocin receptor (OXTR) acts as a key behavioral modulator of the central nervous system, affecting social behavior, stress, affiliation and cognitive functions. Variants of the Oxtr gene are known to influence behavior ...
Metabolic syndrome influences cardiac gene expression pattern at the transcript level in male ZDF rats

Sárközy, Márta; Zvara, Ágnes; Gyemant N; Fekete V; Kocsis-Fodor, Gabriella; Pipis, Judit; Szűcs, Gergő; Csonka, Csaba; Puskás, László; Ferdinandy, Péter; Csont, Tamás Bálint (2013)

ABSTRACT: BACKGROUND: Metabolic syndrome (coexisting visceral obesity, dyslipidemia, hyperglycemia, and hypertension) is a prominent risk factor for cardiovascular morbidity and mortality, however, its effect on cardiac ...
MicroRNA interactome analysis predicts post-transcriptional regulation of ADRB2 and PPP3R1 in the hypercholesterolemic myocardium

Agg B; Baranyai T; Makkos A; Vető, Borbála; Faragó, Nóra; Zvara, Ágnes; Giricz, Zoltán; Veres, Dániel; Csermely, Péter; Arányi, Tamás; Puskás, László; Varga, Zoltán; Ferdinandy, Péter (2018)

Little is known about the molecular mechanism including microRNAs (miRNA) in hypercholesterolemia-induced cardiac dysfunction. We aimed to explore novel hypercholesterolemia-induced pathway alterations in the heart by an ...
Population pharmacogenomics and personalized medicine research in Hungary

Sipeky, Csilla; Keri Gy; Kiss, András; Kopper, László; Matolcsy, András; Tímár, József; Molnár, Mária Judit; Nagy L; Németh, György; Peták, István; Raskó, István; Falus, András; Melegh, Béla (2010)
Structure-function analysis of peroxidasin provides insight into the mechanism of collagen IV crosslinking

Lázár, Enikő; Péterfi, Zalán; Sirokmány, Gábor; Kovács, Hajnal Anna; Klement, Éva; Medzihradszky F., Katalin; Geiszt, Miklós (2015)

Basement membranes provide structural support and convey regulatory signals to cells in diverse tissues. Assembly of collagen IV into a sheet-like network is a fundamental mechanism during the formation of basement membranes. ...
Syndecan-4 promotes cytokinesis in a phosphorylation-dependent manner.

Keller-Pintér, Anikó; Bottka, Sándor Előd; Tímár, József; Kulka, Janina; Katona, Róbert László; Dux, László; Deák, Ferenc; Szilák, László (2010)

During mitosis, cells detach, and the cell-matrix interactions become restricted. At the completion of cytokinesis, the two daughter cells are still connected transiently by an intercellular bridge (ICB), which is subjected ...
The phosphomimetic mutation of syndecan-4 binds and inhibits Tiam1 modulating Rac1 activity in PDZ interaction-dependent manner

Keller-Pinter, Anikó; Ughy, Bettina; Domoki, Mónika; Pettkó-Szandtner, Aladár; Letoha T; Tóvári, József; Tímár, József; Szilák, László (2017)

The small GTPases of the Rho family comprising RhoA, Rac1 and Cdc42 function as molecular switches controlling several essential biochemical pathways in eukaryotic cells. Their activity is cycling between an active GTP-bound ...

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tallózása szerző szerint "MTA Szegedi Biológiai Kutatóközpont"

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