Browsing by Author "Nguyen VT"

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  • Periyasamy M; Patel H; Lai CF; Nguyen VT; Nevedomskaya E; Harrod A; Russell R; Remenyi J; Ochocka AM; Thomas RS; Fuller-Pace F; Győrffy, Balázs; Caldas C; Navaratnam N; Carroll JS; Zwart W; Coombes RC; Magnani L; Buluwela L; Ali S (2015)
    Estrogen receptor alpha (ERalpha) is the key transcriptional driver in a large proportion of breast cancers. We report that APOBEC3B (A3B) is required for regulation of gene expression by ER and acts by causing C-to-U ...
  • Magnani L; Patten DK; Nguyen VT; Hong SP; Steel JH; Patel N; Lombardo Y; Faronato M; Gomes AR; Woodley L; Page K; Guttery D; Primrose L; Fernandez Garcia D; Shaw J; Viola P; Green A; Nolan N; Ellis IO; Rakha EA; Shousha S; Lam EW; Győrffy, Balázs; Lupien M; Coombes RC (2015)
    Over 30% of ERalpha breast cancer patients develop relapses and progress to metastatic disease despite treatment with endocrine therapies. The pioneer factor PBX1 translates epigenetic cues and mediates estrogen induced ...

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