tallózása szerző szerint "Pénzváltó Zsófia"

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A network-based target overlap score for characterizing drug combinations: High correlation with cancer clinical trial results

Ligeti Balázs; Pénzváltó Zsófia; Roberto Vera; Győrffy Balázs; Pongor Sándor (2015)

Drug combinations are highly efficient in systemic treatment of complex multigene diseases such as cancer, diabetes, arthritis and hypertension. Most currently used combinations were found in empirical ways, which limits ...
Identifying Resistance Mechanisms against Five Tyrosine Kinase Inhibitors Targeting the ERBB/RAS Pathway in 45 Cancer Cell Lines

Pénzváltó Zsófia; Tegze Bálint; Szász Attila Marcell; Sztupinszki Zsófia; Likó István; Szendrői Attila; Schäfer R; Győrffy Balázs (2013)

Because of the low overall response rates of 10-47% to targeted cancer therapeutics, there is an increasing need for predictive biomarkers. We aimed to identify genes predicting response to five already approved tyrosine ...
Validation of RNAi Silencing Efficiency Using Gene Array Data shows 18.5% Failure Rate across 429 Independent Experiments

Munkácsy Gyöngyi; Sztupinszki Zsófia; Herman Péter; Bán Bence; Pénzváltó Zsófia; Szarvas Nóra; Győrffy Balázs (2016)

No independent cross-validation of success rate for studies utilizing small interfering RNA (siRNA) for gene silencing has been completed before. To assess the influence of experimental parameters like cell line, transfection ...

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