tallózása szerző szerint "Tekes, Kornélia"

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An update of SGLT1 and SGLT2 inhibitors in early phase diabetes-type 2 clinical trials

Adeghate, Ernest; Mohsin, Sahar; Adi, Faisal; Ahmed, Fares; Yahya, Ali; Kalász, Huba; Tekes, Kornélia; Adeghate, Ernest A (2019)

Introduction: More than 424 million adults have diabetes mellitus (DM). This number is expected to increase to 626 million by 2045. The majority (90-95%) of people with DM has type 2-diabetes (T2DM). The continued prevalence ...
An update on therapies for the treatment of diabetes-induced osteoporosis.

Mohsin, Sahar; Baniyas, May MYH; AlDarmaki, Reem SMH; Tekes, Kornélia; Kalász, Huba; Adeghate, Ernest A (2019)

Introduction: Currently, 424 million people aged between 20 and 79 years worldwide are diabetic. More than 25% of adults aged over 65 years in North America have Type 2 diabetes mellitus (DM). Diabetes-induced osteoporosis ...
Comparative lipophilicity of morphine derivatives

Kalász, Huba; Doležal R,; Tekes, Kornélia; Magyar, Kálmán; Csermely T,; Hosztafi, Sándor (2015)
Decreased plasma nociceptin/orphanin FQ levels after acute coronary syndromes

Csobay Novák, Csaba; Sótonyi, Péter; Krepuska, Miklós; Zima, Endre István; N Szilagyi; Sz Toth; Szeberin, Zoltán; Acsády, György; Merkely, Béla Péter; Tekes, Kornélia (2012)
Distribution of N-methyl-14C-labeled selegiline in the rat

Tekes, Kornélia; Zita Pöstényi,; Erzsébet B Faigl,; Magyar, Kálmán; András Polyák,; Trencsényi, György; Kalász, Huba (2015)
Distribution of Nociceptin in Pancreatic Islet Cells of Normal and Diabetic Rats

Tariq S,; Rashed H,; Nurulain SM,; Emerald BS,; Koturan S,; Tekes, Kornélia (2015)

OBJECTIVES: Nociceptin has been reported to play an important role in the regulation of pancreatic exocrine secretion. Most of the studies performed on nociceptin are mainly physiological rather than morphological in nature. ...
Dose-Dependent Tissue Distribution of K117, a Bis-pyridinium Aldoxime, in Rats

Kalász, Huba; Karvaly, Gellért; Musilek, Kamil; Kuca, Kamil; Young-Sik, Jung; Malawska, Barbara; Adeghate, Ernest A.; Nurulain, Syed M.; Szepesy, Judit; Zelles, Tibor; Tekes, Kornélia (2019)
Effect of nociceptin on insulin release in normal and diabetic rat pancreas

Adeghate, Ernest Akingunula; Saeed, Zulqarnain; D'Souza, Crystal; Tariq, Saeed; Kalász, Huba; Tekes, Kornélia; Adeghate, Ernest Akingunula (2018)

Nociceptin (NC), also known as Orphanin FQ, is a brain peptide involved in the regulation of pain, but its role in the endocrine pancreas is poorly understood. The present study examines the pattern of distribution of NC ...
Efficacy of N-Acetylcysteine, Glutathione, and Ascorbic Acid in Acute Toxicity of Paraoxon to Wistar Rats: Survival Study

Nurulain SM,; Ojha S,; Tekes, Kornélia; Shafiullah M,; Kalász, Huba (2015)
HPLC Analysis and Blood–Brain Penetration of 20-Hydroxyecdysone Diacetonide

Kalász, Huba; Hunyadi, Attila; Tekes, Kornélia; Dolesal R,; Karvaly, Gellért Balázs (2017)
HPLC analysis and detection of l-deprenyl

Csomor V,; Laufer, Rudolf; Pöstényi, Zita; Kalász, Huba; Adeghate, Ernest Akingunola; Tekes, Kornélia (2014)
HPLC analysis of blood–brain barrier penetration of 4-fluorodeprenyl

Pöstényi, Zita; Tekes, Kornélia; Tóth-Molnár, Edit; Kalász, Huba (2015)
HPLC Monitoring of the Microsomal Stability of Rutin and Quercetin

Szőke, Éva; Petroianu G,; Tekes, Kornélia; Benko B,; Szegi, Péter; Laufer, Rudolf (2009)

Reversed-phase HPLC has been used to monitor the concentration of the two major Chamomile components rutin and quercetin during rat liver microsomal treatment. The possibility of microsomal oxidative metabolism or stability ...
Metabolism of Selegiline [(-)-Deprenyl)]

Kalász, Huba; Magyar, Kálmán; Szőke, Éva; Adeghate, Ernest Akingunola; Adem, A; Tekes, Kornélia (2014)

Selegiline [(-)-deprenyl] is used to treat patients with Parkinson's disease. Nevertheless, in much higher doses it has beneficial effects in depression, and dementia of the aged patients. Selegiline undergoes a complex ...
Monitoring by HPLC of chamomile flavonoids exposed to rat liver microsomal metabolism

Petroianu G,; Szőke, Éva; Kalász, Huba; Szegi, Péter; Laufer, Rudolf; Darvas, Ferenc; Tekes, Kornélia (2009)

Three major flavonoid chamomile components (quercetin, apigenin-7-O- glucoside and rutin) were subjected to oxidative metabolism by cytochrome P-450 of rat liver microsomal preparations. Changes over time in their respective ...
Monitoring the Level of 14C-Labelled Selegiline Following Oral Administration

Kalász, Huba; Tekes, Kornélia; Faigl EB,; Pöstényi Z,; Berekméri, Eszter; Karvaly, Gellért Balázs; Adeghate, Ernest Akingunola (2017)
Pharmacokinetics of K117 and K127, two novel antidote candidates to treat Tabun poisoning.

Tekes, Kornélia; Karvaly, Gellért; Nurulain, Syed; Kuca, Kamil; Musilek, Kamil; Adeghate, Ernest; Jung, Young-Sik; Kalász, Huba (2019)

K117 and K127 are bis-pyridinium aldoximes but K117 is a bis-pyridinium bis-aldoxime while K127 has only one single aldoxime in addition to its amide substituent. Is there any difference in pharmacokinetics in these compounds ...
Pharmacokinetics of Two Chlorine-Substituted Bis-Pyridinium Mono-Aldoximes with Regenerating Effect on Butyrylcholinesterase

Kalász, Huba; Szimrók, Zoltán; Karvaly, Gellért Balázs; Adeghate, Jennifer; Tekes, Kornélia (2020)

Our aim was to find chlorine-substituted antidotes against organophosphate poisoning and compare their pharmacokinetics to their parent compound, K-203. White male Wistar rats were intramuscularly injected with K-203, K-867 ...
Uterus-Relaxing Effects of Nociceptin and Nocistatin: Studies on Preterm and Term-Pregnant Human Myometrium In vitro

Deák, Beáta; Klukovits A,; Kormányos Z,; Tekes, Kornélia; Ducza, Eszter; Gáspár, Róbert (2013)

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