tallózása szerző szerint "Vellai, Tibor"

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  • Complex regulation of autophagy in cancer - integrated approaches to discover the networks that hold a double-edged sword 
    Kubisch J; Türei, Dénes; Földvári-Nagy, László; Dunai ZA; Zsakai L; Varga, Máté; Vellai, Tibor; Csermely, Péter; Korcsmáros, Tamás (2013)
    Autophagy, a highly regulated self-degradation process of eukaryotic cells, is a context-dependent tumor-suppressing mechanism that can also promote tumor cell survival upon stress and treatment resistance. Because of this ...
  • Identification of critical paralog groups with indispensable roles in the regulation of signaling flow 
    Módos, Dezső; Brooks J; Fazekas D; Ari, Eszter; Vellai, Tibor; Csermely, Péter; Korcsmáros, Tamás; Földvári-Nagy Lászlóné Lenti, Katalin (2016)
    Extensive cross-talk between signaling pathways is required to integrate the myriad of extracellular signal combinations at the cellular level. Gene duplication events may lead to the emergence of novel functions, leaving ...
  • SignaFish: A Zebrafish-Specific Signaling Pathway Resource 
    Csalyi K,; Fazekas, Dávid; Kadlecsik, Tamás; Turei D,; Gul L,; Módos, Dezső; Demeter, Amanda; Földvári-Nagy Lászlóné Lenti, Katalin; Csermely, Péter; Vellai, Tibor; Korcsmáros, Tamás; Varga, Máté (2016)
    Understanding living systems requires an in-depth knowledge of the signaling networks that drive cellular homeostasis, regulate intercellular communication, and contribute to cell fates during development. Several resources ...
  • SignaLink 2 - a signaling pathway resource with multi-layered regulatory networks 
    Fazekas D,; Koltai M,; Türei, Dénes; Módos, Dezső; Palfy M,; Dúl, Zoltán; Zsákai, Lilian; Földvári-Nagy Lászlóné Lenti, Katalin; Farkas, Illés; Vellai, Tibor; Csermely, Péter; Korcsmáros, Tamás (2013)
    ABSTRACT: BACKGROUND: Signaling networks in eukaryotes are made up of upstream and downstream subnetworks. The upstream subnetwork contains the intertwined network of signaling pathways, while the downstream regulatory ...
  • Starvation-response may not involve Atg1-dependent autophagy induction in non-unikont parasites 
    Földvári-Nagy, László; Ari, Eszter; Csermely, Péter; Korcsmáros, Tamás; Vellai, Tibor (2014)
    Autophagy, the lysosome-mediated self-degradation process, is implicated in survival during starvation in yeast, Dictyostelium and animals. In these eukaryotic taxa (collectively called Unikonts), autophagy is induced ...
  • Suppression of AMPK/aak-2 by NRF2/SKN-1 down-regulates autophagy during prolonged oxidative stress 
    Kosztelnik, Mónika; Kurucz, Anita; Papp, Diána; Jones, Emily; Kovácsné Sigmond, Tímea Ilona; Barna, János; Traka Maria, H; Lőrincz, Tamás; Szarka, András; Bánhegyi, Gábor; Vellai, Tibor; Korcsmáros, Tamás; Kapuy, Orsolya (2019)
    NF-E2-related factor 2 (NRF2) transcription factor has a fundamental role in cell homeostasis maintenance as one of the master regulators of oxidative and electrophilic stress responses. Previous studies have shown that a ...
  • Teaching the bioinformatics of signaling networks: an integrated approach to facilitate multi-disciplinary learning 
    Korcsmáros, Tamás; Dunai Zsuzsanna A; Vellai, Tibor; Csermely, Péter (2013)
    The number of bioinformatics tools and resources that support molecular and cell biology approaches is continuously expanding. Moreover, systems and network biology analyses are accompanied more and more by integrated ...