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Browsing by Author "Zádor, Ferenc"

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Biochemical and pharmacological characterization of three opioid-nociceptin hybrid peptide ligands reveals substantially differing modes of their actions.

Erdei, Anna; Borbély, Adina; Magyar, Anna; Taricska, Nóra; Perczel, András; Zsíros, Ottó; Garab, Győző; Szűcs, Edina; Ötvös, Ferenc; Zádor, Ferenc; Balogh, Mihály; Al-Khrasani, Mahmoud; Benyhe, Sándor (2018)

In an attempt to design opioid-nociceptin hybrid peptides, three novel bivalent ligands, H-YGGFGGGRYYRIK-NH2, H-YGGFRYYRIK-NH2 and Ac-RYYRIKGGGYGGFL-OH were synthesized and studied by biochemical, pharmacological, biophysical ...
Efficacy-based perspective to overcome reduced opioid analgesia of advanced painful diabetic neuropathy in rats

Balogh, Mihály; Zádor, Ferenc; Zádori, S. Zoltán; Shaqura, Mohammed; Király, Kornél P.; Mohammadzadeh, Amir; Varga, K. Bence; Lázár, Bernadette; Mousa, A. Shaaban; Hosztafi, Sándor; Riba, Pál; Benyhe, Sándor; Gyires, Klára; Schäfer, Michael; Fürst, Susanna; Al-Khrasani, Mahmoud (2019)

Reduction of the opioid analgesia in diabetic neuropathic pain (DNP) results from mu-opioid receptor (MOR) reserve reduction. Herein, we examined the antinociceptive and antiallodynic actions of a novel opioid agonist ...
Low dosage of rimonabant leads to anxiolytic-like behavior via inhibiting expression levels and G-protein activity of kappa opioid receptors in a cannabinoid receptor independent manner

Zádor, Ferenc; Lénárt, Nikolett; Csibrány, Balázs; Sántha, Miklós; Molnár, Máté; Tuka, Bernadett; Samavati, Reza; Klivényi, Péter; Vécsei, László; Marton, Annamária; Vizler, Csaba; Nagy, M. György; Borsodi, Anna; Benyhe, Sándor; Páldy, Estera (2015)

What is known There is an increasing number of studies demonstrating the direct effect of the cannabinoid receptor 1 (CB1) antagonist/inverse agonist rimonabant on the opioid system. The kappa opioid receptors (KORs) are ...

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