The reduced derivative of α-conotoxin MI, a 14 amino acid peptide is characterized by NMR-pH titrations and molecular dynamics simulations to determine the protonation constants of the nine basic moieties, including four ...
Ágg, Bence; Császár, Andrea; Szalay-Bekő, Máté; V. Veres, Dániel; Mizsei, Réka; Ferdinandy, Péter; Csermely, Péter; A. Kovács, István(2019)
Motivation: Network visualizations of complex biological datasets usually result in 'hairball' images, which do not discriminate network modules.
Results: We present the EntOptLayout Cytoscape plug-in based on a recently ...
The genetic analysis of early-onset Parkinsonian disorder (EOPD) is part of the clinical diagnostics. Several genes have been implicated in the genetic background of Parkinsonism, which is clinically indistinguishable from ...
Vera Alvarez, Roberto; Pongor, Lorinc Sandor; Mariño-Ramírez, Leonardo; Landsman, David(2019)
The quantification of RNA sequencing (RNA-seq) abundance using a normalization method that calculates transcripts per million (TPM) is a key step to compare multiple samples from different experiments. TPMCalculator is a ...