Identification, quantification and isolation of lignans (Lig-s: arctiin, arctigenin and matairesinol) and sesquilignans (SLig-s: lappaol A, isolappaol A, lappaol C and isolappaol C), in Cnicus benedictus L. fruit (CBfr) ...
Szabó, Zoltán István; Szőcs, Levente; Horváth, Péter; Komjati, B; Nagy, József; Janoska, A; Muntean, DL; Noszál, Béla; Tóth, Gergő(2016)
A sensitive and validated liquid chromatography with mass spectrometry method was developed for the enantioseparation of the racemic mixture of pomalidomide, a novel, second-generation immunomodulatory drug, using ...
Complex formation between the selective serotonin reuptake inhibitor drug (S)-dapoxetine (Dpx) and [small beta]-, [gamma]-, and methylated [gamma]-cyclodextrins (CyDs) was studied by complementary experimental techniques. ...
Aminomorphinans are a relatively young class of opioid drugs among which substances of high in vitro efficacy and favorable in vivo action are found. We report the synthesis and pharmacological evaluation of novel ...
Sustained analgesia is crucial for patients suffering from long-acting pain. Ester derivatives of morphine could enhance the lipophilicity of morphine; consequently its transdermal delivery as well as its duration of action ...
The migration behavior and separation of 13 quinolone antibacterials were investigated by capillary electrophoresis (CE). In order to predict the electrophoretic mobility, the protonation macroconstants of all the compounds ...
Interactions between thyroid hormone alpha and beta receptors and the eight protonation microspecies of each of the main thyroid hormones (thyroxine, liothyronine, and reverse liothyronine) were investigated and quantitated ...