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  • Circadian regulation of human peripheral neutrophils 
    Ella, Krisztina; Csépányi-Kömi, Roland; Káldi, Krisztina (2016)
    Neutrophils are the most abundant leukocytes in human blood. Beside being essential responders in bacterial and fungal infections, they also contribute to tissue reactions in many autoimmune and inflammatory diseases. ...
  • Circadian regulation of neutrophils: Control by a cell-autonomous clock or systemic factors? 
    Ella, Krisztina; Mócsai, Attila; Káldi, Krisztina (2018)
    BACKGROUND: The circadian time-measuring system enables the organism to anticipate and effectively respond to regular daily changes in the environment and is therefore a crucial factor of adaptation. A large body of ...
  • Circulating activin A is a novel prognostic biomarker in malignant pleural mesothelioma - A multi-institutional study 
    Hoda, M Alireza; Dong, Yawen; Rózsás, Anita; Klikovits, Thomas; László, Viktória; Bahil, Ghanim; Paul, Stockhammer; Judit, Ozsvar; Marko, Jakopovic; Miroslav, Samarzija; Luka, Brcic; Mátyás, Bendek; Ildikó, Szirtes; Glen, Reid; Michaela, B Kirschner; Steven, C Kao; Isabelle, Opitz; Walter, Weder; Thomas, Frauenfelder; Thi Dan Linh, Nguyen-Kim; Clemens, Aigner; Walter, Klepetko; Nico, van Zandwijk; Walter, Berger; Döme, Balázs; Michael, Grusch; Hegedűs, Balázs (2016)
    INTRODUCTION: The deregulation of activin expression is often observed in various malignancies. Previous studies indicate that activin A plays a protumourigenic role in malignant pleural mesothelioma (MPM). The aim of the ...
  • Circulating and tissue expression levels of YKL-40 in renal cell cancer 
    Vom Dorp F; Tschirdewahn S; Niedworok C; Reis H; Krause H; Kempkensteffen C; Busch J; Kramer G; Shariat SF; Nyirády, Péter; Rubben H; Szarvas, Tibor (2016)
    PURPOSE: Blood levels of YKL-40 are elevated in various malignancies and other inflammatory diseases. Moreover, higher YKL-40 levels, have consequently been shown to correlate with poor prognosis in several cancers. The ...
  • Circulating blood cells and extracellular vesicles in acute cardioprotection 
    Davidson, Sean M; Andreadou, Ioanna; Barile, Lucio; Birnbaum, Yochai; Cabrera-Fuentes, Hector A; Cohen, Michael V; Downey, James M; Girao, Henrique; Pagliaro, Pasquale; Penna, Claudia; Pernow, John; Preissner, Klaus T; Ferdinandy, Péter; EU-CARDIOPROTECTION, COST Action (2019)
  • Circulating CLA+T lymphocytes as peripheral cell biomarkers in T-cell-mediated skin diseases 
    Ferran M,; Romeu ER,; Rincón C,; Sacrista M,; Giménez Arnau AM,; Holló, Péter; Jókai, Hajnalka (2013)
  • Circulating Clusterin and Osteopontin Levels in Asthma and Asthmatic Pregnancy 
    Dombai Brigitta; Ivancsó István; Bikov András; Oroszi Dóra; Bohács Anikó; Müller, Veronika; Rigó János; Vásárhelyi Barna; Losonczy György; Tamási Lilla (2017)
    Asthma in pregnancy poses a risk of adverse outcomes. Osteopontin and clusterin emerged as asthma biomarkers; however, their circulating levels during pregnancy are unknown yet. This cross-sectional study investigated ...
  • Circulating complement component 4d (C4d) correlates with tumor volume, chemotherapeutic response and survival in patients with malignant pleural mesothelioma 
    Klikovits T; Stockhammer P; Laszlo V; Dong Y; Hoda MA; Ghanim B; Opitz I; Frauenfelder T; Nguyen-Kim TDL; Weder W; Berger W; Grusch M; Aigner C; Klepetko W; Döme, Balázs; Rényi-Vámos, Ferenc István; Oehler R; Hegedűs, Balázs (2017)
    Only limited information is available on the role of complement activation in malignant pleural mesothelioma (MPM). Thus, we investigated the circulating and tissue levels of the complement component 4d (C4d) in MPM. Plasma ...
  • Circulating endothelial cells, bone marrow-derived endothelial progenitor cells and proangiogenic haematopoietic cells in cancer: From biology to therapy 
    Döme, Balázs; Tímár, József; Ladányi, Andrea; Paku, Sándor; Rényi-Vámos, Ferenc István; Klepetko, Walter; Lang, György; Döme, Péter; Bogos, Krisztina; Tóvári, József (2009)
    Vascularization, a hallmark of tumorigenesis, is classically thought to occur exclusively through angiogenesis (i.e. endothelial sprouting). However, there is a growing body of evidence that endothelial progenitor cells ...
  • Circulating exosomal and Argonaute-bound microRNAs in preeclampsia 
    Biró, Orsolya; Fóthi Ábel; Alasztics, Bálint; Nagy, Bálint; Orbán, Tamás I.; Rigó, János (2019)
  • Circulating fibrinogen is a prognostic and predictive biomarker in malignant pleural mesothelioma. 
    Ghanim B; Hoda MA; Klikovits T; Winter MP; Alimohammadi A; Grusch M; Döme Balázs; Arns B; Schenk P; Jakopovic M; Samarzija M; Brcic L; Filipits M; Laszlo Viktoria; Klepetko W; Berger W; Hegedüs Balázs (2014)
    Background:To investigate the clinical utility of pretreatment plasma fibrinogen levels in malignant pleural mesothelioma (MPM) patients.Methods:A retrospective multicenter study was performed in histologically proven MPM ...
  • Circulating ficolin-2 and ficolin-3 in normal pregnancy and pre-eclampsia. 
    Halmos, Amrita; Rigó, János Jr.; Szijártó, János; Füst, György; Prohászka, Zoltán; Molvarec, Attila (2012)
    Ficolins are soluble molecules of the innate immune system that recognize carbohydrate molecules on microbial pathogens, apoptotic and necrotic cells. They act through two distinct routes: initiating the lectin pathway of ...
  • Circulating heat shock protein 70 (HSPA1A) in normal and pathological pregnancies 
    Molvarec, Attila; Tamási, Lilla; Losonczy, György; Madách, Krisztina; Prohászka, Zoltán; Rigó, János Jr. (2010)
    Heat shock proteins (Hsps) are ubiquitous and phylogenetically conserved molecules. They are usually considered to be intracellular proteins with molecular chaperone and cytoprotective functions. However, Hsp70 (HSPA1A) ...
  • Circulating microRNAs as minimal residual disease biomarkers in childhood acute lymphoblastic leukemia 
    Rzepiel, Andrea; Kutszegi, Nóra; Gézsi, András; Sági, Judit C; Egyed, Bálint; Péter, György; Butz, Henriett; Nyírő, Gábor; Müller, Judit; Kovács, Gábor; Szalai, Csaba; Semsei, Ágnes F; Erdélyi, Dániel (2019)
    Treatment stratification based on bone marrow minimal residual disease (MRD) at set time points has resulted in considerably improved survival in pediatric acute lymphoblastic leukemia (ALL). Treatment response is assessed ...
  • Circulating miRNA Expression Profiling in Primary Aldosteronism 
    Decmann, Ábel; Nyírő, Gábor; Darvasi, Ottó; Turai, Péter István; Bancos, Irina; Kaur, Ravinder Jeet; Pezzani, Raffaele; Iacobone, Maurizio; Kraljevic, Ivana; Kastelan, Darko; Parasiliti-Caprino, Mirko; Maccario, Mauro; Nirschl, Nina; Heinrich, Daniel; Reincke, Martin; Patócs, Attila Balázs; Igaz, Péter (2019)
  • Circulating mitochondrial stress 70 protein/mortalin and cytosolic Hsp70 in blood: Risk indicators in colorectal cancer. 
    Jubran R; Kocsis, Judit; Garam, Nóra; Malati E; Gombos, Tímea; Barabás, Lóránd; Gráf, László; Prohászka, Zoltán; Fishelson Z (2017)
    Mitochondrial mortalin and cytosolic Hsp70 are essential chaperones overexpressed in cancer cells. Our goals were to reproduce our earlier findings of elevated circulating levels of mortalin and Hsp70 in colorectal cancer ...
  • Circulating periostin level in asthmatic pregnancy 
    Ivancsó, István; Bohács, Anikó; Szalay, Balázs; Toldi, Gergely; Szilasi, Magdolna Emma; Müller, Veronika; Losonczy, György; Rigó, János; Vásárhelyi, Barna; Tamási, Lilla (2016)
    OBJECTIVE: Asthma often complicates pregnancy and represents a risk for complications. Periostin is considered as a biomarker of asthma; however, as it also plays a role in normal gestation, pregnancy may influence circulating ...
  • Circulating P-Selectin Glycoprotein Ligand 1 and P-Selectin Levels in Obstructive Sleep Apnea Patients 
    Horváth, Péter; Lázár, Zsófia; Gálffy, Gabriella; Puskás, Rita; Kunos, László; Losonczy, György; Mészéros, Martina; Tárnoki, Ádám Domonkos; Tárnoki, Dávid László; Bikov, András (2020)
    Purpose Obstructive sleep apnea (OSA) is characterized by chronic intermittent hypoxia which induces inflammation in blood vessels leading to the development of cardiovascular comorbidities. Several studies implicated the ...
  • Circulating soluble urokinase-type plasminogen activator receptor in obstructive sleep apnoea 
    Böcskei, Renáta; Mészáros, Martina; Tárnoki, Ádám Domonkos; Tárnoki, Dávid László; Kunos, László; Lázár, Zsófia; Bikov, András (2020)
    Background and Objectives: Obstructive sleep apnoea (OSA) is associated with heightened systemic inflammation and a hypercoagulation state. Soluble urokinase-type plasminogen activator receptor (suPAR) plays a role in ...
  • Circulating survivin levels in healthy and asthmatic pregnancy. 
    Bikov András; Böcskei Renáta; Eszes Noémi; Bohács Anikó; Losonczy György; Rigó János; Horváth Ildikó; Tamási Lilla (2014)
    BACKGROUND: Asthma is one of the most common conditions which complicate pregnancy. Pro- and anti-apoptotic mechanisms can be modulated by asthma accompanying pregnancy. Survivin, an anti-apoptotic protein has been implicated ...