Folyóiratcikkek tallózása szerző szerint "Csala, Miklós"

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Analytical Approaches for the Quantitation of Redox-active Pyridine Dinucleotides in Biological Matrices

Somogyi A; Horvai, György; Csala, Miklós; Tóth, Blanka (2016)
BGP-15 Protects Mitochondria in Acute, Acetaminophen Overdose Induced Liver Injury

Sarnyai, Farkas; Szekerczés, Tímea; Csala, Miklós; Sümegi, Balázs; Szarka, András; Schaff, Zsuzsa; Mandl, József (2019)

Acetaminophen (APAP) induced hepatotoxicity involves activation of c-Jun amino-terminal kinase (JNK), mitochondrial damage and ER stress. BGP-15, a hydroximic acid derivative, has been reported to have hepatoprotective ...
Composition of the redox environment of the endoplasmic reticulum and sources of hydrogen peroxide

Margittai, Éva; Enyedi, Balázs; Csala, Miklós; Geiszt, Miklós; Bánhegyi, Gábor (2015)
Cytosolic localization of NADH cytochrome b5 oxidoreductase (Ncb5or)

Zámbó, Veronika; Tóth M; Schlachter K; Szelényi, Péter; Sarnyai, Farkas; Lotz, Gábor; Csala, Miklós; Kereszturi, Éva (2016)
Entrance of electrons to acyl-CoA desaturation

Csala, Miklós (2015)
Epigallocatechin-3-Gallate (EGCG) Promotes Autophagy-Dependent Survival via Influencing the Balance of mTOR-AMPK Pathways upon Endoplasmic Reticulum Stress

Holczer, Marianna; Besze B; Zámbó, Veronika; Csala, Miklós; Bánhegyi, Gábor; Kapuy, Orsolya (2018)
Inhibition of microsomal cortisol production by (–)-epigallocatechin-3-gallate through a redox shift in the endoplasmic reticulum — A potential new target for treating obesity-related diseases

Szelényi, Péter; Révész, Katalin; Konta, Laura; Tüttő A; Mandl, József; Kereszturi, Éva; Csala, Miklós (2013)

Conversion of cortisone to cortisol by 11β-hydroxysteroid dehydrogenase type 1 (11βHSD1) in the endoplasmic reticulum (ER) of the target cells is a major determinant of glucocorticoid action, and plays an important ...
Lipotoxicity in the liver

Zámbó, Veronika; Simon-Szabó, Laura; Szelényi, Péter; Kereszturi, Éva; Bánhegyi, Gábor; Csala, Miklós (2013)

Obesity due to excessive food intake and the lack of physical activity is becoming one of the most serious public health problems of the 21st century. With the increasing prevalence of obesity, non-alcoholic fatty liver ...
Luminal accumulation of newly synthesized morphine-3-glucuronide in rat liver microsomal vesicles.

Révész, Katalin; Tóth, Blanka; Staines AG; Coughtrie MW; Mandl, József; Csala, Miklós (2013)

Morphine is converted to morphine 3-beta-D-glucuronide (M3G) by the UDP-glucuronosyltransferase Ugt2b1 in the endoplasmic reticulum (ER) of rat liver. Because of its luminal localization, UGT activity requires UDP-glucuronate ...
Metformin Attenuates Palmitate-Induced Endoplasmic Reticulum Stress, Serine Phosphorylation of IRS-1 and Apoptosis in Rat Insulinoma Cells

Simon-Szabó, Laura; Kokas M; Mandl, József; Kéri, György; Csala, Miklós (2014)

Lipotoxicity refers to cellular dysfunctions caused by elevated free fatty acid levels playing a central role in the development and progression of obesity related diseases. Saturated fatty acids cause insulin resistance ...
Microsomal pre-receptor cortisol production is inhibited by resveratrol and epigallocatechin gallate through different mechanisms

Szelényi, Péter; Somogyi, Anna; Sarnyai, Farkas; Zámbó, Veronika; Simon-Szabó, Laura; Kereszturi, Éva; Csala, Miklós (2019)
Minireview: Endoplasmic reticulum stress: Control in protein, lipid, and signal homeostasis

Mandl, József; Mészáros, Tamás; Bánhegyi, Gábor; Csala, Miklós (2013)

Endoplasmic reticulum (ER) stress is a regulatory mechanism that allows cells to adapt to a series of metabolic, redox, and other environmental changes. The role of ER stress was first identified in the maintenance of ...
Natural mutations lead to enhanced proteasomal degradation of human Ncb5or, a novel flavoheme reductase

Kálmán, Fanni Sára; Lizák, Beáta; Nagy, Szilvia Krisztina; Mészáros, Tamás; Zámbó, Veronika; Mandl, József; Csala, Miklós; Kereszturi, Éva (2013)

NADH cytochrome b5 oxidoreductase (Ncb5or) protects β-cells against oxidative stress and lipotoxicity. The predominant phenotype of lean Ncb5or-null mouse is insulin-dependent diabetes due to β-cell death. This suggests ...
Novel Crizotinib–GnRH conjugates revealed the significance of lysosomal trapping in GnRH-based drug delivery systems

Murányi, József; Varga, Attila; Gyulavári, Pál; Pénzes, Kinga; Németh, Csilla Emese; Csala, Miklós; Pethő, Lilla; Csámpai, Antal; Halmos, Gábor; Peták, István; Vályi-Nagy, István (2019)

Several promising anti-cancer drug–GnRH (gonadotropin-releasing hormone) conjugates have been developed in the last two decades, although none of them have been approved for clinical use yet. Crizotinib is an effective ...
The Potential Impact of Connexin 43 Expression on Bcl-2 Protein Level and Taxane Sensitivity in Head and Neck Cancers–In Vitro Studies

Gurbi, Bianka; Brauswetter, Diána; Varga, Attila; Gyulavári, Pál; Pénzes, Kinga; Murányi, József; Zámbó, Veronika; Birtalan, Ede; Krenács, Tibor; Becker, David Laurence; Csala, Miklós; Vályi-Nagy, István; Peták, István; Dános, Kornél (2019)
Zsírsavtúltengés - inzulinrezisztencia és béta-sejt-halál [Hyper-free fatty acidemia - insulin resistance and β-cell death]

Csala, Miklós (2016)

The increasing prevalence of type 2 diabetes correlates with the rapid spread of obesity worldwide. Adipocytes are strained by the demand of excessive storage, and the local inflammation accelerates triglyceride turnover, ...

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Folyóiratcikkek tallózása szerző szerint "Csala, Miklós"

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