Browsing Folyóiratcikkek by Author "Iordanov, Iordan"

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Abolition of mitochondrial substrate-level phosphorylation by itaconic acid produced by LPS-induced Irg1 expression in cells of murine macrophage lineage

Németh, Beáta; Dóczi, Judit; Csete, Dániel; Kacsó, Gergely; Ravasz, Dóra; Daniel Adams; Kiss, Gergely; Nagy, Ádám Miklós; Horváth, Gergő; Tretter, László; Mócsai, Attila; Csépányi-Kömi, Roland; Iordanov, Iordan; Ádám, Veronika; Chinopoulos, Christos (2016)

Itaconate is a nonamino organic acid exhibiting antimicrobial effects. It has been recently identified in cells of macrophage lineage as a product of an enzyme encoded by immunoresponsive gene 1 (Irg1), acting on the citric ...
Enzyme activity and selectivity filter stability of ancient TRPM2 channels were simultaneously lost in early vertebrates

Iordanov, Iordan; Tóth, Balázs; Szöllösi, András; Csanády, László (2019)

Transient Receptor Potential Melastatin 2 (TRPM2) is a cation channel important for the immune response, insulin secretion, and body temperature regulation. It is activated by cytosolic ADP ribose (ADPR) and contains a ...
Ruling out pyridine dinucleotides as true TRPM2 channel activators reveals novel direct agonist ADP-ribose-2'-phosphate

Tóth, Balázs; Iordanov, Iordan; Csanády, László (2015)

Transient receptor potential melastatin 2 (TRPM2), a Ca(2+)-permeable cation channel implicated in postischemic neuronal cell death, leukocyte activation, and insulin secretion, is activated by intracellular ADP ribose ...
Selective profiling of N- And C-terminal nucleotide-binding sites in a TRPM2 channel

Tóth, Balázs; Iordanov, Iordan; Csanády, László (2020)

Transient receptor potential melastatin 2 (TRPM2) is a homotetrameric Ca2+-permeable cation channel important for the immune response, body temperature regulation, and insulin secretion, and is activated by cytosolic Ca2+ ...
The proposed channel-enzyme transient receptor potential melastatin 2 does not possess ADP ribose hydrolase activity

Iordanov, Iordan; Mihályi, Csaba; Tóth, Balázs; Csanády, László (2016)

Transient Receptor Potential Melastatin 2 (TRPM2) is a Ca(2+)-permeable cation channel essential for immunocyte activation, insulin secretion, and postischemic cell death. TRPM2 is activated by ADP ribose (ADPR) binding ...
Two transgenic mouse models for beta subunit components of succinate-CoA ligase yielding pleiotropic metabolic alterations

Kacsó, Gergely; Ravasz, Dóra; Dóczi, Judit; Németh, Beáta; Madgar O,; Iordanov, Iordan; Gál, Anikó; Molnár, Mária Judit; Nagy, Zsolt; Patócs, Attila Balázs; Ádám, Veronika; Chinopoulos, Christos (2016)

Succinate-CoA ligase is a heterodimer enzyme composed of Suclg1 -alpha- and a substrate-specific Sucla2 or Suclg2 -beta- subunit yielding ATP or GTP, respectively. In humans, the deficiency of this enzyme leads to ...

Now showing items 1-6 of 6

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Browsing Folyóiratcikkek by Author "Iordanov, Iordan"

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