tallózása szerző szerint "Varga, Zoltán"

21-40 / 42

Integrative characterization of chronic cigarette smoke-induced cardiopulmonary comorbidities in a mouse model

Kemény, Ágnes; Csekő, Kata; Szitter, István; Varga, Zoltán; Bencsik, Péter; Kiss, Krisztina; Halmosi, Róbert; Deres, László; Erős, Krisztián; Perkecz A; Kereskai, László; Horváthné László, Terézia; Kiss T; Ferdinandy, Péter; Helyes, Zsuzsanna (2017)

Cigarette smoke-triggered inflammatory cascades and consequent tissue damage are the main causes of chronic obstructive pulmonary disease (COPD). There is no effective therapy and the key mediators of COPD are not identified ...
Interplay of oxidative, nitrosative/nitrative stress, inflammation, cell death and autophagy in diabetic cardiomyopathy

Varga, Zoltán; Giricz, Zoltán; Liaudet L; Hasko G; Ferdinandy, Péter; Pacher, Pál (2015)

Diabetes is a recognized risk factor for cardiovascular diseases and heart failure. Diabetic cardiovascular dysfunction also underscores the development of diabetic retinopathy, nephropathy and neuropathy. Despite the ...
In vivo MRI and ex vivo histological assessment of the cardioprotection induced by ischemic preconditioning, postconditioning and remote conditioning in a closed-chest porcine model of reperfused acute myocardial infarction: importance of microvasculature

Baranyai, Tamás; Giricz, Zoltán; Varga, Zoltán; Koncsos, Gábor; Lukovic D; Makkos, András; Sárközy, Márta; Pavo N; Jakab A; Czimbalmos, Csilla; Vágó, Hajnalka; Ruzsa, Zoltán; Tóth, Levente; Garamvölgyi, Rita; Merkely, Béla Péter; Schulz R; Gyongyosi M; Ferdinandy, Péter (2017)

BACKGROUND: Cardioprotective value of ischemic post- (IPostC), remote (RIC) conditioning in acute myocardial infarction (AMI) is unclear in clinical trials. To evaluate cardioprotection, most translational animal studies ...
Isolated hypercholesterolemia leads to steatosis in the liver without affecting the pancreas

Csonka, Csaba; Baranyai, Tamás; Tiszlavicz, László; Fébel, Hedvig; Szűcs, Gergő; Varga, Zoltán; Sárközy, Márta; Puskás, László; Antal, Otilia Tamara; Siska, Andrea; Földesi, Imre; Ferdinandy, Péter; Czakó, László; Csont, Tamás Bálint (2017)
JDP2 overexpression provokes cardiac dysfunction in mice

Heger J; Bornbaum J; Wurfel A; Hill C; Brockmann N; Gáspár, Renáta; Pálóczi, János; Varga, Zoltán; Sárközy, Márta; Bencsik, Péter; Csont, Tamás Bálint; Török, Szilvia; Kojonazarov B; Schermuly RT; Bongler K; Parahuleva M; Ferdinandy, Péter; Schulz R; Euler G (2018)

The transcriptional regulator JDP2 (Jun dimerization protein 2) has been identified as a prognostic marker for patients to develop heart failure after myocardial infarction. We now performed in vivo studies on JDP2-overexpressing ...
Low dose cranial irradiation-induced cerebrovascular damage is reversible in mice

Sándor, Nikolett; Walter, Fruzsina; Bocsik, Alexandra; Sántha, Petra; Schilling-Tóth, Boglárka; Léner, Violetta; Varga, Zoltán; Kahán, Zsuzsanna; Deli, Mária Anna; Sáfrány, Géza; Hegyesi, Hargita (2014)

BACKGROUND: High-dose radiation-induced blood-brain barrier breakdown contributes to acute radiation toxicity syndrome and delayed brain injury, but there are few data on the effects of low dose cranial irradiation. Our ...
Low-Dose Endotoxin Induces Late Preconditioning, Increases Peroxynitrite Formation, and Activates STAT3 in the Rat Heart

Pipicz, Márton; Kocsis-Fodor, Gabriella; Sarvary-Arantes L; Bencsik, Péter; Varga, Zoltán; Ferdinandy, Péter; Csont, Tamás Bálint (2017)

Administration of low-dose endotoxin (lipopolysaccharide, LPS) 24 h before a lethal ischemia induces pharmacological late preconditioning. The exact mechanism of this phenomenon is not clear. Here we aimed to investigate ...
Mechanical stability and fibrinolytic resistance of clots containing fibrin, DNA and histones

Longstaff C; Varjú, Imre; Sótonyi, Péter; Szabó, László; Krumrey M; Hoell A; Bóta, Attila; Varga, Zoltán; Komorowicz, Erzsébet; Kolev, Kraszimir Nikolaev (2013)
MicroRNA-25-dependent up-regulation of NADPH oxidase 4 (NOX4) mediates hypercholesterolemia-induced oxidative/nitrative stress and subsequent dysfunction in the heart

Varga, Zoltán; Kupai, Krisztina; Szűcs, Gergő; Gáspár, Renáta; Pálóczi, János; Faragó, Nóra; Zvara, Ágnes; Puskás, László; Rázga, Zsolt; Tiszlavicz, László; Bencsik, Péter; Görbe, Anikó; Csonka, Csaba; Ferdinandy, Péter; Csont, Tamás Bálint (2013)

Diet-induced hypercholesterolemia leads to oxidative/nitrative stress and subsequent myocardial dysfunction. However, the regulatory role of microRNAs in this phenomenon is unknown. We aimed to investigate, whether ...
MicroRNA interactome analysis predicts post-transcriptional regulation of ADRB2 and PPP3R1 in the hypercholesterolemic myocardium

Agg B; Baranyai T; Makkos A; Vető, Borbála; Faragó, Nóra; Zvara, Ágnes; Giricz, Zoltán; Veres, Dániel; Csermely, Péter; Arányi, Tamás; Puskás, László; Varga, Zoltán; Ferdinandy, Péter (2018)

Little is known about the molecular mechanism including microRNAs (miRNA) in hypercholesterolemia-induced cardiac dysfunction. We aimed to explore novel hypercholesterolemia-induced pathway alterations in the heart by an ...
MicroRNAs associated with ischemia/reperfusion injury and cardioprotection by ischemic pre- and postconditioning: ProtectomiRs

Varga, Zoltán; Zvara, Ágnes; Faragó, Nóra; Kocsis-Fodor, Gabriella; Pipicz, Márton; Gáspár, Renáta; Bencsik, Péter; Görbe, Anikó; Csonka, Csaba; Puskás, László; Thum T; Csont, Tamás Bálint; Ferdinandy, Péter (2014)

We aimed to characterize early changes in microRNA expression in acute cardioprotection by ischemic pre- and postconditioning in rat hearts. Hearts isolated from male Wistar rats were subjected to i) time-matched non-ischemic ...
miR-125b is a protectomiR: A rising star for acute cardioprotection

Varga, Zoltán; Ágg, Bence; Ferdinandy, Péter (2018)

Myocardial infarction and resulting heart failure remain the leading causes of death worldwide. Therefore, novel therapies are required to protect the heart against the detrimental effects of acute ischemia/reperfusion ...
Moderate inhibition of myocardial matrix metalloproteinase-2 by ilomastat is cardioprotective

Bencsik, Péter; Pálóczi, János; Kocsis-Fodor, Gabriella; Pipis, Judit; Belecz, István; Varga, Zoltán; Csonka, Csaba; Görbe, Anikó; Csont, Tamás Bálint; Ferdinandy, Péter (2014)

Pharmacological inhibition of matrix metalloproteinase-2 (MMP-2) is a promising target for acute cardioprotection against ischemia/reperfusion injury. Therefore, here we investigated if the MMP inhibitor ilomastat administered ...
Myostatin and IGF-I signaling in end-stage human heart failure: a qRT-PCR study

Baán, Júlia Aliz; Varga, Zoltán; Przemyslaw Leszek; Mariusz Kusmierczyk; Baranyai, Tamás; Dux, László; Ferdinandy, Péter; Thomas Braun; Mendler, Luca (2015)
Nagarse treatment of cardiac subsarcolemmal and interfibrillar mitochondria leads to -artefacts in mitochondrial protein quantification

Koncsos, Gábor; Varga, Zoltán; Baranyai, Tamás; Ferdinandy, Péter; Schulz R; Giricz, Zoltán; Boengler K (2018)

INTRODUCTION: In the heart, subsarcolemmal (SSM), interfibrillar (IFM) and perinuclear mitochondria represent three subtypes of mitochondria. The most commonly used protease during IFM isolation is the nagarse, however, ...
On-line visualization of ischemic burden during repetitive ischemia/reperfusion

Pavo N; Emmert MY; Giricz, Zoltán; Varga, Zoltán; Ankersmit HJ; Maurer G; Hoerstrup SP; Ferdinandy, Péter; Wu J; Gyöngyösi, Mariann (2014)
Posttranslational modifications of calcium/calmodulin-dependent protein kinase IIdelta and its downstream signaling in human failing hearts

Rajtik T; Goncalvesova E; Varga, Zoltán; Leszek P; Kusmierczyk M; Hulman M; Kyselovic J; Ferdinandy, Péter; Adameova A (2017)

BACKGROUND: In human failing hearts (HF) of different origin (coronary artery disease-CAD, dilated-DCM, restrictive and hypertrophic cardiomyopathy-OTHER), we investigated the active forms of Ca2+/calmodulin-dependent ...
Protection by the NO-Donor SNAP and BNP against Hypoxia/Reoxygenation in Rat Engineered Heart Tissue

Görbe, Anikó; Eder A; Varga, Zoltán; Pálóczi, János; Hansen A; Ferdinandy, Péter; Eschenhagen T (2015)

In vitro assays could replace animal experiments in drug screening and disease modeling, but have shortcomings in terms of functional readout. Force-generating engineered heart tissues (EHT) provide simple automated ...
Protection of neonatal rat cardiac myocytes against radiation-induced damage with agonists of growth hormone-releasing hormone

Kiscsatári, Laura; Varga, Zoltán; Schally AV; Gáspár, Renáta; Nagy, Csilla Terézia; Giricz, Zoltán; Ferdinandy, Péter; Fábián, Gabriella; Kahán, Zsuzsanna; Görbe, Anikó (2016)

Despite the great clinical significance of radiation-induced cardiac damage, experimental investigation of its mechanisms is an unmet need in medicine. Beneficial effects of growth hormone-releasing hormone (GHRH) agonists ...
Selegiline reduces adiposity induced by high-fat, high-sucrose diet in male rats

Nagy CT; Koncsos, Gábor; Varga, Zoltán; Baranyai T; Tuza S; Kassai F; Ernyey AJ; Gyertyan I; Kiraly K; Oláh, Attila; Radovits, Tamás; Merkely, Béla Péter; Bukosza N; Szénási, Gábor; Hamar, Péter; Mathe D; Szigeti K; Pelyhe C; Jelemensky M; Onodi Z; Helyes, Zsuzsanna; Schulz R; Giricz, Zoltán; Ferdinandy, Péter (2018)

BACKGROUND AND PURPOSE: Incidence and severity of obesity is increasing worldwide. To date, efficient and safe pharmacological tools to treat or prevent obesity have not been developed. Certain monoamine-oxidase (MAO) ...

21-40 / 42

Keresés

Összetett keresés

Tallózás

Teljes repozitórumban

Hozzáférésem

Bejelentkezés

tallózása szerző szerint "Varga, Zoltán"

DSpace/Manakin Repository

tallózása szerző szerint "Varga, Zoltán"

Keresés

Tallózás

Teljes repozitórumban

Hozzáférésem