tallózása szerző szerint "Jabado, N"

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  • Cytogenetic Prognostication Within Medulloblastoma Subgroups 
    Shih, DJ; Northcott, PA; Remke, M; Korshunov, A; Ramaswamy, V; Kool, M; Luu, B; Yao, Y; Wang, X; Dubuc, AM; Garzia, L; Peacock, J; Mack, SC; Wu, X; Rolider, A; Morrissy, AS; Cavalli, FM; Jones, DT; Zitterbart, K; Faria, CC; Schuller, U; Kren, L; Kumabe, T; Tominaga, T; Shin, Ra Y; Garami, Miklós; Hauser, Péter; Chan, JA; Robinson, S; Bognár, László; Klekner, Álmos; Saad, AG; Liau, LM; Albrecht, S; Fontebasso, A; Cinalli, G; De Antonellis, P; Zollo, M; Cooper, MK; Thompson, RC; Bailey, S; Lindsey, JC; Di Rocco, C; Massimi, L; Michiels, EM; Scherer, SW; Phillips, JJ; Gupta, N; Fan, X; Muraszko, KM; Vibhakar, R; Eberhart, CG; Fouladi, M; Lach, B; Jung, S; Wechsler-Reya, RJ; Fevre-Montange, M; Jouvet, A; Jabado, N; Pollack, IF; Weiss, WA; Lee, JY; Cho, BK; Kim, SK; Wang, KC; Leonard, JR; Rubin, JB; de Torres, C; Lavarino, C; Mora, J; Cho, YJD; Tabori, U; Olson, JM; Gajjar, A; Packer, RJ; Rutkowski, S; Pomeroy, SL; French, PJ; Kloosterhof, NK; Kros, JM; Van, Meir EG; Clifford, SC; Bourdeaut, F; Delattre, O; Doz, FF; Hawkins, CE; Malkin, D; Grajkowska, WA; Perek-Polnik, M; Bouffet, E; Rutka, JT; Pfister, SM; Taylor, M (2014)
    PURPOSE: Medulloblastoma comprises four distinct molecular subgroups: WNT, SHH, Group 3, and Group 4. Current medulloblastoma protocols stratify patients based on clinical features: patient age, metastatic stage, extent ...
  • Driver mutations in histone H3.3 and chromatin remodelling genes in paediatric glioblastoma 
    Schwartzentruber, J; Korshunov, A; Liu, XY; Jones, DT; Pfaff, E; Jacob, K; Sturm, D; Fontebasso, AM; Quang, DA; Tonjes, M; Hovestadt, V; Albrecht, S; Kool, M; Nantel, A; Konermann, C; Lindroth, A; Jager, N; Rausch, T; Ryzhova, M; Korbel, JO; Hielscher, T; Hauser, Péter; Garami, Miklós; Klekner, Álmos; Bognár, László; Ebinger, M; Schuhmann, MU; Scheurlen, W; Pekrun, A;; Fruhwald, MC; Roggendorf, W; Kramm, C; Durken, M; Atkinson, J; Lepage, P; Montpetit, A; Zakrzewska, M; Zakrzewski, K; Liberski, PP; Dong, Z; Siegel, P; Kulozik, AE; Zapatka, M; Guha, A; Malkin, D; Felsberg, J; Reifenberger, G; von Deimling, A; Ichimura, K; Collins, VP; Witt, H; Milde, T; Witt, O; Zhang, C; Castelo-Branco, P; Lichter, P; Faury, D; Tabori, U; Plass, C; Majewski, J; Pfister, SM; Jabado, N (2012)
    Glioblastoma multiforme (GBM) is a lethal brain tumour in adults and children. However, DNA copy number and gene expression signatures indicate differences between adult and paediatric cases. To explore the genetic events ...
  • Fusion of TTYH1 with the C19MC microRNA cluster drives expression of a brain-specific DNMT3B isoform in the embryonal brain tumor ETMR 
    Kleinman, CL; Gerges, N; Papillon-Cavanagh, S; Sin-Chan, P; Pramatarova, A; Quang, DA; Adoue, V; Busche, S; Caron, M; Djambazian, H; Bemmo, A; Fontebasso, AM; Spence, T; Schwartzentruber, J; Albrecht, S; Hauser, Péter; Garami, Miklós; Klekner, Álmos; Bognár, László; Montes, JL; Staffa, A; Montpetit, A; Berube, P; Zakrzewska, M; Zakrzewski, K; Liberski, PP; Dong, Z; Siegel, PM; Duchaine, T; Perotti, C; Fleming, A; Faury, D; Remke, M; Gallo, M; Dirks, P; Taylor, MD; Sladek, R; Pastinen, T; Chan, JA; Huang, A; Majewski, J; Jabado, N (2014)
    Embryonal tumors with multilayered rosettes (ETMRs) are rare, deadly pediatric brain tumors characterized by high-level amplification of the microRNA cluster C19MC. We performed integrated genetic and epigenetic analyses ...
  • Intertumoral Heterogeneity within Medulloblastoma Subgroups 
    Cavalli, FMG; Remke, M; Rampasek, L; Peacock, J; Shih, DJH; Luu, B; Garzia, L; Torchia, J; Nor, C; Morrissy, AS; Agnihotri, S; Thompson, YY; Kuzan-Fischer, CM; Farooq, H; Isaev, K; Daniels, C; Cho, BK; Kim, SK; Wang, KC; Lee, JY; Grajkowska, WA; Perek-Polnik, M; Vasiljevic, A; Faure-Conter, C; Jouvet, A; Giannini, C; Rao, AAN; Li, KKW; Ng, HK; Eberhart, CG; Pollack, IF; Hamilton, RL; Gillespie, GY; Olson, JM; Leary, S; Weiss, WA; Lach, B; Chambless, LB; Thompson, RC; Cooper, MK; Vibhakar, R; Hauser, Péter; van Veelen, MLC; Kros, JM; French, PJ; Ra, YS; Kumabe, T; Lopez-Aguilar, E; Zitterbart, K; Sterba, J; Finocchiaro, G; Massimino, M; Van, Meir EG; Osuka, S; Shofuda, T; Klekner, Álmos; Zollo, M; Leonard, JR; Rubin, JB; Jabado, N; Albrecht, S; Mora, J; Van, Meter TE; Jung, S; Moore, AS; Hallahan, AR; Chan, JA; Tirapelli, DPC; Carlotti, CG; Fouladi, M; Pimentel, J; Faria, CC; Saad, AG; Massimi, L; Liau, LM; Wheeler, H; Nakamura, H; Elbabaa, SK; Perezpeña-Diazconti, M; Chico Ponce de León, F; Robinson, S; Zapotocky, M; Lassaletta, A; Huang, A; Hawkins, CE; Tabori, U; Bouffet, E; Bartels, U; Dirks, PB; Rutka, JT; Bader, GD; Reimand, J; Goldenberg, A; Ramaswamy, V; Taylor, MD (2017)
    While molecular subgrouping has revolutionized medulloblastoma classification, the extent of heterogeneity within subgroups is unknown. Similarity network fusion (SNF) applied to genome-wide DNA methylation and gene ...
  • Prognostic value of medulloblastoma extent of resection after accounting for molecular subgroup: a retrospective integrated clinical and molecular analysis 
    Thompson, EM; Hielscher, T; Bouffet, E; Remke, M; Luu, B; Gururangan, S; McLendon, RE; Bigner, DD; Lipp, ES; Perreault, S; Cho, YJ; Grant, G; Kim, SK; Lee, JY; Rao, AA; Giannini, C; Li, KK; Ng, HK; Yao, Y; Kumabe, T; Tominaga, T; Grajkowska, WA; Perek-Polnik, M; Low, DC; Seow, WT; Chang, KT; Mora, J; Pollack, IF; Hamilton, RL; Leary, S; Moore, AS; Ingram, WJ; Hallahan, AR; Jouvet, A; Fevre-Montange, M; Vasiljevic, A; Faure-Conter, C;; Shofuda, T; Kagawa, N; Hashimoto, N; Jabado, N; Weil, AG; Gayden, T; Wataya, T; Shalaby, T; Grotzer, M; Zitterbart, K; Sterba, J; Kren, L; Hortobágyi, Tibor; Klekner, Álmos; Laszlo, B; Pócza, Tímea; Hauser, Péter; Schuller, U; Jung, S; Jang, WY; French, PJ; Kros, JM; van Veelen, MC; Massimi, L; Leonard, JR; Rubin, JB; Vibhakar, R; Chambless, LB; Cooper, MK; Thompson, RC; Faria, CC; Carvalho, A; Nunes, S; Pimentel, J; Fan, X; Muraszko, KM; Lopez-Aguilar, E; Lyden, D; Garzia, L; Shih, DJ; Kijima, N; Schneider, C; Adamski, J; Northcott, PA; Kool, M; Jones, DT; Chan, JA; Nikolic, A; Garre, ML; Van, Meir EG; Osuka, S; Olson, JJ; Jahangiri, A; Castro, BA; Gupta, N; Weiss, WA; Moxon-Emre, I; Mabbott, DJ; Lassaletta, A; Hawkins, CE; Tabori, U; Drake, J; Kulkarni, A; Dirks, P; Rutka, JT; Korshunov, A; Pfister, SM; Packer, RJ; Ramaswamy, V; Taylor, MD (2016)
    BACKGROUND: Patients with incomplete surgical resection of medulloblastoma are controversially regarded as having a marker of high-risk disease, which leads to patients undergoing aggressive surgical resections, so-called ...
  • Subgroup-Specific Prognostic Implications of TP53 Mutation in Medulloblastoma 
    Zhukova N; Ramaswamy V; Remke M; Pfaff E; Shih DJ; Martin, DC; Castelo-Branco, P; Baskin, B; Ray, PN; Bouffet, E; von Bueren, AO; Jones, DT; Northcott, PA; Kool, M; Sturm, D; Pugh, TJ; Pomeroy, SL; Cho, YJ; Pietsch, T; Gessi, M; Rutkowski, S; Bognár, László; Klekner, Álmos; Cho, BK; Kim, SK; Wang, KC; Eberhart, CG; Fevre-Montange, M; Fouladi, M; French, PJ; Kros, M; Grajkowska, WA; Gupta, N; Weiss, WA; Hauser, Péter; Jabado, N; Jouvet, A; Jung, S; Kumabe, T; Lach, B; Leonard, JR; Rubin, JB; Liau, LM; Massimi, L; Pollack, IF; Shin, Ra Y; Van, Meir EG; Zitterbart, K; Schuller, U; Hill, RM; Lindsey, JC; Schwalbe, EC; Bailey, S; Ellison, DW; Hawkins, C; Malkin, D; Clifford, SC; Korshunov, A; Pfister, S; Taylor, MD; Tabori, U (2013)
    PURPOSE Reports detailing the prognostic impact of TP53 mutations in medulloblastoma offer conflicting conclusions. We resolve this issue through the inclusion of molecular subgroup profiles. PATIENTS AND METHODS We ...
  • Subgroup-specific structural variation across 1,000 medulloblastoma genomes 
    Northcott, PA; Shih, DJH; Peacock, J; Garzia, L; Sorana Morrissy, A; Zichner, T; Stütz, AM; Korshunov, A; Reimand, J; Schumacher, SE; Beroukhim, R; Ellison, DW; Marshall, CR; Lionel, AC; Mack, S; Dubuc, A; Yao, Y; Ramaswamy, V; Luu, B; Rolider, A; Cavalli, FMG; Wang, X; Remke, M; Wu, X; Chiu, RYB; Chu, A; Chuah, E; Corbett, RD; Hoad, GR; Jackman, SD; Li, Y; Lo, A; Mungall, KL; Ming, Nip K; Qian, JQ; Raymond, AGJ; Thiessen, N; Varhol, RJ; Birol, I; Moore, RA; Mungall, AJ; Holt, R; Kawauchi, D; Roussel, MF; Kool, M; Jones, DTW; Witt, H; Fernandez-L A; Kenney, AM; Wechsler-Reya, RJ; Dirks, P; Aviv, T; Grajkowska, WA; Perek-Polnik, M; Haberler, CC; Delattre, O; Reynaud, SS; Doz, FF; Pernet-Fattet, SS; Cho, B-K; Kim, S-K; Wang, K-C; Scheurlen, W; Eberhart, CG; Fèvre-Montange, M; Jouvet, A; Pollack, IF; Fan, X; Muraszko, KM; Yancey, Gillespie G; Di Rocco, C; Massimi, L; Michiels, EMC; Kloosterhof, NK; French, PJ; Kros, JM; Olson, JM; Ellenbogen, RG; Zitterbart, K; Kren, L; Thompson, RC; Cooper, MK; Lach, B; McLendon, RE; Bigner, DD; Fontebasso, A; Albrecht, S; Jabado, N; Lindsey, JC; Bailey, S; Gupta, N; Weiss, WA; Bognár, László; Klekner, Álmos; Van, Meter TE; Kumabe, T; Tominaga, T; Elbabaa, SK; Leonard, JR; Rubin, JB; Liau, LM; Van, Meir EG; Fouladi, M; Nakamura, H; Cinalli, G; Garami, Miklós; Hauser, Péter; Saad, AG; Iolascon, A; Jung, S; Carlotti, CG; Vibhakar, R; Shin, Ra Y; Robinson, S; Zollo, M; Faria, CC; Chan, JAD; Levy, ML; Sorensen, PHB; Meyerson, M; Pomeroy, SL; Cho, Y-J; Bader, GD; Tabori, U; Hawkins, CE; Bouffet, E; Scherer, SW; Rutka, JT; Malkin, D; Clifford, SC; Jones, SJM; Korbel, JO; Pfister, SM; Marra, MA; Taylor, MD (2012)
    Medulloblastoma, the most common malignant paediatric brain tumour, is currently treated with nonspecific cytotoxic therapies including surgery, whole-brain radiation, and aggressive chemotherapy. As medulloblastoma exhibits ...