tallózása szerző szerint "Őrfi, László"

1-17 / 17

Acid-base profiling of imatinib (Gleevec) and its fragments

Szakács, Zoltán; Béni, Szabolcs; Varga Z,; Őrfi, László; Kéri, György; Noszál, Béla (2005)

The site-specific basicities of imatinib (Gleevec, a new signal transduction inhibitor drug of chronic myeloid leukemia) and two of its fragment compounds were quantitated in terms of protonation macroconstants, microconstants, ...
Activation of HER3 Interferes with Antitumor Effects of Axl Receptor Tyrosine Kinase Inhibitors: Suggestion of Combination Therapy.

Torka R,; Pénzes, Kinga; Gusenbauer S,; Baumann C,; Szabadkai I,; Őrfi, László; Kéri, György (2014)

The Axl receptor tyrosine kinase (RTK) has been established as a strong candidate for targeted therapy of cancer. However, the benefits of targeted therapies are limited due to acquired resistance and activation of alternative ...
Anticytolytic Screen Identifies Inhibitors of Mycobacterial Virulence Protein Secretion

Jan Rybniker; Jeffrey M Chen; Claudia Sala; Ruben C Hartkoorn; Anthony Vocat; Andrej Benjak; Stefanie Boy-Röttger; Ming Zhang; Rita Székely; Zoltán Greff; Őrfi, László; István Szabadkai; János Pató; Kéri, György; Stewart T Cole (2014)
Combined inhibition of AXL, Lyn and p130Cas kinases block migration of triple negative breast cancer cells

Pénzes, Kinga; Baumann C,; Szabadkai I,; Őrfi, László; Kéri, György (2014)
Developing FGFR4 inhibitors as potential anti-cancer agents via in silico design, supported by in vitro and cell-based testing

H K Ho,; Németh, Gábor; Y R Ng,; E Pang,; C Szántai-Kis,; Zsákai, Lilian; Szokol, Bálint; Baska, Ferenc; Őrfi, László; Kéri, György (2013)

Fibroblast growth factor receptor-4 (FGFR4) is a tyrosine kinase with a range of important physiological functions. However, it is also frequently mutated in various cancers and is now generating significant interest as a ...
Discovery and biological evaluation of novel dual EGFR/c-Met inhibitors

Szokol, Bálint; Gyulavári, Pál; Kurkó Ibolya,; Baska, Ferenc; Szántai-Kis Csaba,; Peták, István; Pénzes, Kinga; Őrfi, László; Vántus, Tibor; Kéri, György (2014)
Discovery and optimization of novel benzothiophene-3-carboxamides as highly potent inhibitors of Aurora kinases A and B

Gyulavári, Pál; Szokol, Bálint; Szabadkai, István; Brauswetter, Diána; Bánhegyi, Péter; Varga, Attila; Markó, Péter; Boros, Sándor; Illyés, Eszter; Szántai-Kis, Csaba; Krekó, Marcell; Czudor, Zsófia; Őrfi, László (2018)
Discovery of N-[4-(Quinolin-4-yloxy)phenyl]benzenesulfonamides as Novel AXL Kinase Inhibitors

Szabadkai, I; Torka, R; Garamvölgyi, Rita; Baska, Ferenc; Gyulavári, Pál; Boros, Sándor; Illyes, E; Choidas, A; Ullrich, A; Őrfi, László (2018)

The overexpression of AXL kinase has been described in many types of cancer. Due to its role in proliferation, survival, migration, and resistance, AXL represents a promising target in the treatment of the disease. In this ...
Inclusion complexation of the anticancer drug pomalidomide with cyclodextrins: fast dissolution and improved solubility

Szabó, Zoltán-István; Orbán, György; Borbás, Enikő; Csicsák, Dóra; Kádár, Szabina; Fiser, Béla; Dobó, Máté; Horváth, Péter; Kiss, Eszter; Budai, Lívia; Dobos, Judit; Pálla, Tamás; Őrfi, László; Völgyi, Gergely; Tóth, Gergő (2021)
Mycobacterium tuberculosis ellenes hatoanyagok fejlesztese es szerkezet-hatas osszefuggeseinek vizsgalata.

Baska, Ferenc; Szekely ER,; Szantai-Kis C,; Banhegyi P,; Hegymegi-Barakonyi, Bálint; Zsákai, Lilian; Kéri, György; Őrfi, László (2013)

Tuberculosis is considered to be one of the major health problem not only in the less developed countries but in the economically developed countries as well. Roughly one third of the world's population are infected with ...
NADPH oxidase 4 is expressed in pulmonary artery adventitia and contributes to hypertensive vascular remodeling

Barman SA,; Chen F,; Su Y,; Dimitropoulou C,; Wang Y,; Őrfi, László; Kéri, György (2014)
Pharmacophore and Binding Analysis of Known and Novel B-RAF Kinase Inhibitors

Baska, Ferenc; Szabadkai István,; Sipos, Anna; Breza Nóra,; Szántai-Kis Csaba,; Kékesi, László; Nemes, Zoltán; Baska, Ferenc; Kéri, György; Őrfi, László (2014)
Potencialis antitumor hatasu FGFR inhibitorok fejlesztese.

Zsákai, Lilian; Nemeth G,; Szantai-Kis C,; Greff Z,; Horvath Z,; Szokol, Bálint; Baska, Ferenc; Őrfi, László; Kéri, György (2013)

Fibroblast Growth Factor Receptor (FGFR) family is a sequentially highly related subgroup of membrane proteins consisting of four tyrosine kinase type enzyme: FGFR1, FGFR2, FGFR3 and FGFR4. These are kinases of great ...
Protein Kinase C Drives Sphingomyelin Metabolism in the Nucleus During Cell Proliferation

E Damaskopoulou,; Kéri, György; V Jacob,; R Lazzarini,; S Cataldi,; Őrfi, László (2013)
Synthesis and biological evaluation of novel pyrido[2,3-b]pyrazines inhibiting both erlotinib-sensitive and erlotinib-resistant cell lines.

Kékesi, László; Sipos, Anna; Németh, Gábor; Pato J,; Breza N,; Baska, Ferenc; Őrfi, László; Kéri, György (2013)

A series of novel pyrido[2,3-b]pyrazines were synthesized as potential antitumor agents for erlotinib-resistant tumors. Known signal inhibitor compounds from our Nested Chemical Library were tested in phenotypic assays ...
Synthesis and Evaluation of Phosphorus Containing, Specific CDK9/CycT1 Inhibitors

Németh Gábor,; Greff Zoltán,; Sipos Anna,; Varga Zoltán,; Székely Rita,; Mártonffyné Jászay, Zsuzsa; Béni, Szabolcs; Nemes, Zoltán; Minárovits, János; Kéri, György; Őrfi, László (2014)
TP53 mutation-correlated genes predict the risk of tumor relapse and identify MPS1 as a potential therapeutic kinase in TP53-mutated breast cancers

Győrffy, Balázs; Giulia Bottai,; Jacqueline Lehmann-Ch,; Kéri, György; Őrfi, László (2014)

Breast cancers (BC) carry a complex set of gene mutations that can influence their gene expression and clinical behavior. We aimed to identify genes driven by the TP53 mutation status and assess their clinical relevance ...

1-17 / 17

Keresés

Összetett keresés

Tallózás

Teljes repozitórumban

Hozzáférésem

Bejelentkezés

tallózása szerző szerint "Őrfi, László"

DSpace/Manakin Repository

tallózása szerző szerint "Őrfi, László"

Keresés

Tallózás

Teljes repozitórumban

Hozzáférésem