tallózása szerző szerint "Ferdinandy, Péter"

A találatok rendezése: Rendezés: Találatok:

  • Activation of PPARbeta/delta protects cardiac myocytes from oxidative stress-induced apoptosis by suppressing generation of reactive oxygen/nitrogen species and expression of matrix metalloproteinases 
    Barlaka E; Görbe, Anikó; Gáspár, Renáta; Pálóczi, János; Ferdinandy, Péter; Lazou A (2015)
    Heart failure still remains one of the leading causes of morbidity and mortality worldwide. A major contributing factor is reactive oxygen/nitrogen species (RONS) overproduction which is associated with cardiac remodeling ...
  • Acute hyperglycemia abolishes cardioprotection by remote ischemic perconditioning 
    Baranyai, Tamás; Nagy, Csilla Terézia; Koncsos, Gábor; Onódi, Zsófia; Karolyi-Szabo M; Makkos, András; Varga, Zoltán; Ferdinandy, Péter; Giricz, Zoltán (2015)
    BACKGROUND: Remote ischemic perconditioning (RIPerC) has a promising therapeutic insight to improve the prognosis of acute myocardial infarction. Chronic comorbidities such as diabetes are known to interfere with conditioning ...
  • Adverse Effects on beta-Adrenergic Receptor Coupling: Ischemic Postconditioning Failed to Preserve Long-Term Cardiac Function 
    Schreckenberg R; Bencsik, Péter; Weber M; Abdallah Y; Csonka, Csaba; Gömöri, Kamilla; Kiss, Krisztina; Pálóczi, János; Pipis J; Sárközy, Márta; Ferdinandy, Péter; Schulz R; Schluter KD (2017)
    BACKGROUND: Ischemic preconditioning (IPC) and ischemic postconditioning (IPoC) are currently among the most efficient strategies protecting the heart against ischemia/reperfusion injury. However, the effect of IPC and ...
  • A longevity study with enhancer substances (selegiline, BPAP) detected an unknown tumor-manifestation-suppressing regulation in rat brain 
    Knoll, József; Baghy, Kornélia; Eckhardt S; Ferdinandy, Péter; Garami, Miklós; Hársing, László Gábor; Hauser, Péter; Mervai, Zsolt; Pócza, Tímea; Schaff, Zsuzsa; Schuler, Dezső; Miklya, Ildikó (2017)
    AIMS: First proof to show that (-)-deprenyl/selegiline (DEP), the first selective inhibitor of MAO-B, later identified as the first beta-phenylethylamine (PEA)-derived synthetic catecholaminergic activity enhancer (CAE) ...
  • Alternative Splicing of NOX4 in the Failing Human Heart 
    Varga, Zoltán; Pipicz, Márton; Baán, Júlia Aliz; Baranyai T; Koncsos, Gábor; Leszek P; Kusmierczyk M; Sanchez-Cabo F; Garcia-Pavia P; Brenner, Gábor; Giricz, Zoltán; Csont, Tamás Bálint; Mendler, Luca; Lara-Pezzi E; Pacher, Pál; Ferdinandy, Péter (2017)
    Increased oxidative stress is a major contributor to the development and progression of heart failure, however, our knowledge on the role of the distinct NADPH oxidase (NOX) isoenzymes, especially on NOX4 is controversial. ...
  • Analysis of necroptotic proteins in failing human hearts 
    Szobi A; Goncalvesova E; Varga, Zoltán; Leszek P; Kusmierczyk M; Hulman M; Kyselovic J; Ferdinandy, Péter; Adameova A (2017)
    BACKGROUND: Cell loss and subsequent deterioration of contractile function are hallmarks of chronic heart failure (HF). While apoptosis has been investigated as a participant in the progression of HF, it is unlikely that ...
  • A new potent analgesic agent with reduced liability to produce morphine tolerance 
    Király, Kornél P; Caputi FF,; Hanuska, Adrienn; Kató, Erzsébet; balogh, Mihály; Köles, László; Riba, Pál; Hosztafi, Sándor; Ferdinandy, Péter; Fürst, Zsuzsanna; Al-Khrasani, Mahmoud (2015)
    The therapeutic use of opioids is limited by the development of tolerance to the analgesic effect and the cellular and molecular mechanisms underlying this phenomenon are still not completely understood. For this reason ...
  • Anti-diabetic effect of a preparation of vitamins, minerals and trace elements in diabetic rats: a gender difference 
    Sárközy, Márta; Fekete, Veronika; Szűcs, Gergő; Török, Szilvia; Szűcs, Csilla; Barkányi, Judit; Varga, Zoltán; Földesi, Imre; Csonka, Csaba; Kónya, Csaba; Csont, Tamás Bálint; Ferdinandy, Péter (2014)
    BACKGROUND: Although multivitamin products are widely used as dietary supplements to maintain health or as special medical food in certain diseases, the effects of these products were not investigated in diabetes mellitus, ...
  • Author Correction: MicroRNA interactome analysis predicts post-transcriptional regulation of ADRB2 and PPP3R1 in the hypercholesterolemic myocardium 
    Ágg, Bence; Baranyai, Tamás; Makkos, András; Veto, B; Faragó, Nóra; Zvara, Ágnes; Giricz, Zoltán; Veres, Dániel; Csermely, Péter; Arányi, Tamás; Puskás, László; Varga, Zoltán; Ferdinandy, Péter (2018)
  • Autophagosome formation is required for cardioprotection by chloramphenicol 
    Giricz, Zoltán; Varga, Zoltán; Koncsos, Gábor; Nagy, Csilla Terézia; Görbe, Anikó; Mentzer RM Jr; Gottlieb RA; Ferdinandy, Péter (2017)
    AIMS: Chloramphenicol (CAP), a broad spectrum antibiotic, was shown to protect the heart against ischemia/reperfusion (I/R) injury. CAP also induces autophagy, however, it is not known whether CAP-induced cardioprotection ...
  • Cardiac innervation in acute myocardial ischaemia/reperfusion injury and cardioprotection 
    Hausenloy, Derek J; Bøtker, Hans Erik; Ferdinandy, Péter; Heusch, Gerd; Ng, G André; Redington, Andrew; Garcia-Dorado, David; EU-CARDIOPROTECTION, COST Action (2019)
    Acute myocardial infarction (AMI) and the heart failure (HF) that often complicates this condition, are among the leading causes of death and disability worldwide. To reduce myocardial infarct (MI) size and prevent heart ...
  • Cardiac Nitric Oxide Signalling in Metabolic Syndrome 
    Pechanova O; Varga, Zoltán; Cebova M; Giricz, Zoltán; Pacher, Pál; Ferdinandy, Péter (2015)
    It is well documented that metabolic syndrome (i.e. a group of risk factors, such as abdominal obesity, elevated blood pressure, elevated fasting plasma glucose, high serum triglycerides, and low cholesterol level in ...
  • Cardioprotection by Farnesol: Role of the Mevalonate Pathway 
    Szűcs, Gergő; Murlasits, Zsolt; Török, Szilvia; Kocsis-Fodor, Gabriella; Pálóczi, János; Görbe, Anikó; Csont, Tamás Bálint; Csonka, Csaba; Ferdinandy, Péter (2013)
    Purpose: Farnesol is a key metabolite of the mevalonate pathway and known as an antioxidant. We examined whether farnesol treatment protects the ischemic heart. Methods: Male Wistar rats were treated orally with 0.2, 1, ...
  • Cardioprotection by gene therapy 
    Madonna R; Cadeddu C; Deidda M; Giricz, Zoltán; Madeddu C; Mele D; Monte I; Novo G; Pagliaro P; Pepe A; Spallarossa P; Tocchetti CG; Varga, Zoltán; Zito C; Geng YJ; Mercuro G; Ferdinandy, Péter (2015)
    Ischemic heart disease remains the leading cause of death worldwide. Ischemic pre-, post-, and remote conditionings trigger endogenous cardioprotection that renders the heart resistant to ischemic-reperfusion injury (IRI). ...
  • Cardioprotection by remote ischemic preconditioning of the rat heart is mediated by extracellular vesicles 
    Giricz, Zoltán; Varga, Zoltán; Baranyai, Tamás; Sipos, Péter; Pálóczi, Krisztina; Kittel, Ágnes; Buzás, Edit Irén; Ferdinandy, Péter (2014)
    Remote ischemic preconditioning (RIPC) of the heart is exerted by brief ischemic insults affected on a remote organ or a remote area of the heart before a sustained cardiac ischemia. To date, little is known about the ...
  • Catalyzing Transcriptomics Research in Cardiovascular Disease 
    Gomes, Clarissa Pedrosa da C; Ágg, Bence; Andova, Andrejaana; Arslan, Serdal; Baker, Andrew; Barteková, Monika; Beis, Dimitris; Betsou, Fay; Wettinger, Stephanie Bezzina; Bugarski, Branko; Condorelli, Gianluigi; Silva, Gustavo José Justo da; Danilin, Sabrina; Gonzalo-Calvo, David de; Buil, Alfonso; Carmo-Fonseca, Maria; Enguita, Francisco J; Felekkis, Kyriacos; Ferdinandy, Péter; Gyöngyösi, Mariann; Hackl, Matthias; Karaduzovic-Hadziabdic, Kanita; Hellemans, Jan; Heymans, Stephane; Hlavackova, Markéta; Hoydal, Morten Andre; Jankovic, Aleksandra; Jusic, Amela; Kardassis, Dimitris; Kerkelä, Risto; Kuster, Gabriela M; Lakkisto, Päivi; Leszek, Przemyslaw; Lustrek, Mitja; Maegdefessel, Lars; Martelli, Fabio; Novella, Susana; O'Brien, Timothy; Papaneophytou, Christos; Pedrazzini, Thierry; Pinet, Florence; Popescu, Octavian; Potočnjak, Ines; Robinson, Emma; Sasson, Shlomo; Scholz, Markus; Simionescu, Maya; Stoll, Monika; Varga, Zoltan V; Vinciguerra, Manlio; Xuereb, Angela; Yilmaz, Mehmet Birhan; Emanueli, Costanza; Devaux, Yvan; EU-CardioRNA Cost Action CA17129 (2019)
    Cardiovascular disease (CVD) remains the leading cause of death worldwide and, despite continuous advances, better diagnostic and prognostic tools, as well as therapy, are needed. The human transcriptome, which is the set ...
  • Cholesterol-enriched diet inhibits cardioprotection by ATP-sensitive K+ channel activators cromakalim and diazoxide 
    Csonka, Csaba; Kupai, Krisztina; Bencsik, Péter; Görbe, Anikó; Pálóczi, János; Zvara, Ágnes; Puskás, László; Csont, Tamás Bálint; Ferdinandy, Péter (2014)
    It has been previously shown that hyperlipidemia interferes with cardioprotective mechanisms. Here we investigated the interaction of hyperlipidemia with cardioprotection induced by pharmacological activators of ATP-sensitive ...
  • Circulating blood cells and extracellular vesicles in acute cardioprotection 
    Davidson, Sean M; Andreadou, Ioanna; Barile, Lucio; Birnbaum, Yochai; Cabrera-Fuentes, Hector A; Cohen, Michael V; Downey, James M; Girao, Henrique; Pagliaro, Pasquale; Penna, Claudia; Pernow, John; Preissner, Klaus T; Ferdinandy, Péter; EU-CARDIOPROTECTION, COST Action (2019)
  • Co-Activation of Nuclear Factor-kappaB and Myocardin/Serum Response Factor Conveys the Hypertrophy Signal of High Insulin Levels in Cardiac Myoblasts 
    Madonna R; Geng YJ; Bolli R; Rokosh G; Ferdinandy, Péter; Patterson C; De Caterina R (2014)
    Background and Objective: Hyperinsulinemia contributes to cardiac hypertrophy and heart failure in patients with the metabolic syndrome and type 2 diabetes. Here high circulating levels of tumor necrosis factor (TNF)-alpha ...
  • Co-expression of glycosylated aquaporin-1 and transcription factor NFAT5 contributes to aortic stiffness in diabetic and atherosclerosis-prone mice 
    Madonna, Rosalinda; Doria, Vanessa; Görbe, Anikó; Cocco, Nino; Ferdinandy, Péter; Geng, Yong-Jian; Pierdomenico, Sante Donato; De Caterina, Raffaele (2020)
    Increased stiffness characterizes the early change in the arterial wall with subclinical atherosclerosis. Proteins inducing arterial stiffness in diabetes and hypercholesterolaemia are largely unknown. This study aimed at ...