Browsing by Author "Jabado N"

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  • Jacob K; Albrecht S; Sollier C; Faury D; Sader E; Montpetit A; Serre D; Hauser, Péter; Garami, Miklós; Bognár, László; Hanzély Z; Montes JL; Atkinson J; Farmer JP; Bouffet E; Hawkins C; Tabori U; Jabado N (2009)
    BACKGROUND: Juvenile pilocytic astrocytomas (JPA), a subgroup of low-grade astrocytomas (LGA), are common, heterogeneous and poorly understood subset of brain tumours in children. Chromosomal 7q34 duplication leading to ...
  • Schwartzentruber J; Korshunov A; Liu X-Y; Jones DTW; Pfaff E; Jacob K; Sturm D; Fontebasso AM; Quang D-AK; Tönjes M; Hovestadt V; Albrecht S; Kool M; Nantel A; Konermann C; Lindroth A; Jäger N; Rausch T; Ryzhova M; Korbel JO; Hielscher T; Hauser, Péter; Garami, Miklós; Klekner, Álmos; Bognár, László; Ebinger M; Schuhmann MU; Scheurlen W; Pekrun A; Frühwald MC; Roggendorf W; Kramm C; Dürken M; Atkinson J; Lepage P; Montpetit A; Zakrzewska M; Zakrzewski K; Liberski PP; Dong Z; Siegel P; Kulozik AE; Zapatka M; Guha A; Malkin D; Felsberg J; Reifenberger G; Von Deimling A; Ichimura K; Collins VP; Witt H; Milde T; Witt O; Zhang C; Castelo-Branco P; Lichter P; Faury D; Tabori U; Plass C; Majewski J; Pfister SM; Jabado N (2012)
  • Qu HQ; Jacob K; Fatet S; Ge B; Barnett D; Delattre O; Faury D; Montpetit A; Solomon L; Hauser, Péter; Garami, Miklós; Bognár, László; Hanzély Z; Mio R; Farmer JP; Albrecht S; Polychronakos C; Hawkins C; Jabado N (2010)
  • Faury D; Nantel A; Dunn SE; Guiot MC; Haque T; Hauser, Péter; Garami, Miklós; Bognár, László; Hanzély Z; Liberski PP; Lopez-Aguilar E; Valera ET; Tone LG; Carret AS; Del Maestro RF; Gleave M; Montes JL; Pietsch T; Albrecht S; Jabado N (2007)
    PURPOSE: Pediatric glioblastoma (pGBM) is a rare, but devastating brain tumor. In contrast to GBM in adults (aGBM), little is known about the mechanisms underlying its development. Our aim is to gain insight into the ...
  • Torchia J; Picard D; Lafay-Cousin L; Hawkins C E; Kim S -K; Letourneau; Ra Y -S; Ho K C; Chan T S Y; Sin-Chan P; Dunham C; Yip S; Ng H -K; Lu J -Q; Albrecht S; Pimentel J; Chan J A; Somers G R; Zielenska M; Faria C C; Roque L; Baskin B; Birks D; Foreman N; Strother D; Klekner, Álmos; Garami, Miklós; Hauser, Péter; Hortobágyi, Tibor; Bognár L; Wilson B; Hukin J; Carret A -S; Van Meter T E; Nakamura H; Toledano H; Fried I; Fults D; Wataya T; Fryer C; Eisenstat D D; Scheineman K; Johnston D; Michaud J; Zelcer S; Hammond R; Ramsay D A; Fleming A J; Lulla R R; Fangusaro J R; Sirachainan N; Larbcharoensub N; Hongeng S; Barakzai M A; Montpetit A; Stephens D; Grundy R G; Schüller U; Nicolaides T; Tihan T; Phillips J; Taylor M D; Rutka J T; Dirks P; Bader G D; Warmuth-Metz M; Rutkowski S; Pietsch T; Judkins A R; Jabado N; Bouffet E; Huang A (2015)
    BACKGROUND: Rhabdoid brain tumours, also called atypical teratoid rhabdoid tumours, are lethal childhood cancers with characteristic genetic alterations of SMARCB1/hSNF5. Lack of biological understanding of the substantial ...
  • Fontebasso AM; Schwartzentruber J; Khuong-Quang D-A; Liu X-Y; Sturm D; Korshunov A; Jones DTW; Witt H; Kool M; Albrecht S; Fleming A; Hadjadj D; Busche S; Lepage P; Montpetit A; Staffa A; Gerges N; Zakrzewska M; Zakrzewski K; Liberski PP; Hauser, Péter; Garami, Miklós; Klekner, Álmos; Bognár, László; Zadeh G; Faury D; Pfister SM; Jabado N; Majewski J (2013)
    Recurrent mutations affecting the histone H3.3 residues Lys27 or indirectly Lys36 are frequent drivers of pediatric high-grade gliomas (over 30 % of HGGs). To identify additional driver mutations in HGGs, we investigated ...
  • Fontebasso AM; Shirinian M; Khuong-Quang DA; Bechet D; Gayden T; Kool M; De Jay N; Jacob K; Gerges N; Hutter B; Seker-Cin H; Witt H; Montpetit A; Brunet S; Lepage P; Bourret G; Klekner, Álmos; Bognar L; Hauser, Péter; Garami, Miklós; Farmer JP; Montes JL; Atkinson J; Lambert S; Kwan T; Korshunov A; Tabori U; Collins VP; Albrecht S; Faury D; Pfister SM; Paulus W; Hasselblatt M; Jones DT; Jabado N (2015)
    Pilocytic astrocytoma (PA) is the most common brain tumor in children but is rare in adults, and hence poorly studied in this age group. We investigated 222 PA and report increased aneuploidy in older patients. Aneuploid ...
  • Al-Halabi H; Nantel A; Klekner, Álmos; Guiot MC; Albrecht S; Hauser, Péter; Garami, Miklós; Bognár, László; Kavan P; Gerges N; Shirinian M; Roberge D; Muanza T; Jabado N (2011)
  • Fontebasso AM; Papillon-Cavanagh S; Schwartzentruber J; Nikbakht H; Gerges N; Fiset PO; Bechet D; Faury D; De Jay N; Ramkissoon LA; Corcoran A; Jones DT; Sturm D; Johann P; Tomita T; Goldman S; Nagib M; Bendel A; Goumnerova L; Bowers DC; Leonard JR; Rubin JB; Alden T; Browd S; Geyer JR; Leary S; Jallo G; Cohen K; Gupta N; Prados MD; Carret AS; Ellezam B; Crevier L; Klekner, Álmos; Bognár, László; Hauser, Péter; Garami, Miklós; Myseros J; Dong Z; Siegel PM; Malkin H; Ligon AH; Albrecht S; Pfister SM; Ligon KL; Majewski J; Jabado N; Kieran MW (2014)
    Pediatric midline high-grade astrocytomas (mHGAs) are incurable with few treatment targets identified. Most tumors harbor mutations encoding p.Lys27Met in histone H3 variants. In 40 treatment-naive mHGAs, 39 analyzed by ...
  • Lassaletta A; Zapotocky M; Mistry M; Ramaswamy V; Honnorat M; Krishnatry R; Stucklin AG; Zhukova N; Arnoldo A; Ryall S; Ling C; McKeown, T; Loukides J; Cruz O; de Torres C; Ho CY; Packer RJ; Tatevossian R; Qaddoumi I; Harreld JH; Dalton JD; Mulcahy-Levy J; Foreman N; Karajannis MA; Wang SY; Snuderl M; Rao AN; Giannini C; Kieran M; Ligon KL; Garre ML; Nozza P; Mascelli S; Raso A; Mueller S; Nicolaides T; Silva K; Perbet R; Vasiljevic A; Conter CF; Frappaz D; Leary S; Crane C; Chan A; Ng HK; Shi ZF; Mao Y; Finch E; Eisenstat D; Wilson B; Carret AS; Hauser, Péter; Sumerauer D; Krskova L; Larouche V; Fleming A; Zelcer S; Jabado N; Rutka JT; Dirks P; Taylor MD; Chen SY; Bartels U; Huang A; Ellison DW; Bouffet E; Hawkins C; Tabori U (2017)
    Purpose BRAF V600E is a potentially highly targetable mutation detected in a subset of pediatric low-grade gliomas (PLGGs). Its biologic and clinical effect within this diverse group of tumors remains unknown. Patients and ...

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