tallózása szerző szerint "Márk, Ágnes"

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Activity and complexes of mTOR in diffuse large B-cell lymphomas-a tissue microarray study

Sebestyén, Anna; Sticz TB; Márk, Ágnes; Hajdu, Melinda; Tímár, Botond; Nemes, Karolina; Nagy, Noémi; Váradi, Zsófia; Kopper, László (2012)

Diffuse large B-cell lymphoma is a heterogeneous group of diseases with different responses to therapy. Targeting mTOR (mammalian target of rapamycin) offers a new approach to improve the treatment. mTOR inhibitors are ...
Az mTOR (mammalian target of rapamycin) aktivitás jelentősége humán lymphomákban

Márk, Ágnes (2014)

Neoplastic processes, tumor growth, and tumor cell proliferation and survival are often due to the altered activation of different signaling pathways. The increased activity of PI3K/AKT/mTOR signaling has been shown to be ...
Az mTOR (mammalian target of rapamycin) aktivitás jelentősége humán lymphomákban

Márk, Ágnes (2013)
Characterisation of bioenergetic pathways and related regulators by multiple assays in human tumour cells

Jeney, András; Hujber, Zoltán; Szoboszlai, Norbert; Fullár, Alexandra; Oláh, Lászlóné; Pap É; Márk, Ágnes; Kriston, Csilla; Kralovánszky, Judit; Kovalszky, Ilona; Vékey, Károly; Sebestyén, Anna (2016)

Background: Alterations in cellular metabolism are considered as hallmarks of cancers, however, to recognize these alterations and understand their mechanisms appropriate techniques are required. Our hypothesis was to ...
Characteristic mTOR activity in Hodgkin-lymphomas offers a potential therapeutic target in high risk disease - a combined tissue microarray, in vitro and in vivo study.

Márk, Ágnes; Hajdu, Melinda; Varadi Z; Sticz TB; Nagy, Noémi; Csomor, Judit; Berczi L; Varga V; Csóka, Monika; Kopper, László; Sebestyén, Anna (2013)

BACKGROUND: Targeting signaling pathways is an attractive approach in many malignancies. The PI3K/Akt/mTOR pathway is activated in a number of human neoplasms, accompanied by lower overall and/or disease free survival. ...
Expression of certain leukemia/lymphoma related microRNAs and its correlation with prognosis in childhood acute lymphoblastic leukemia

Nemes, Karolina; Csóka, Monika; Nagy, Noémi; Márk, Ágnes; Zsófia Váradi; Titanilla Dankó; Kovács, Gábor; Kopper, László; Sebestyén, Anna (2015)
Expression of mTORC1/2-related proteins in primary and brain metastatic lung adenocarcinoma

Krencz, Ildikó; Sebestyén, Anna; Fábián, Katalin; Márk, Ágnes; Moldvay, Judit; Khoor A; Kopper, László; Pápay, Judit (2017)

Brain metastases are common complications of adenocarcinomas of the lung and are associated with a poor prognosis. Although an increasing amount of data indicates that dysregulated activity of mammalian target of rapamycin ...
Growth inhibitory effect of rapamycin in Hodgkin-lymphoma cell lines characterized by constitutive NOTCH1 activation

Nagy, Noémi; Hajdu, Melinda; Márk, Ágnes; Király, Péter Attila; Toth M; Danko T; Csóka, Monika; Sebestyén, Anna (2016)

Growing evidence suggests that deregulation of signalling elements of Notch and mammalian target of rapamycin (mTOR) pathways contribute to tumorigenesis. These signals play important roles in cellular functions and ...
mTOR Pathway As a Potential Target In a Subset of Human Medulloblastoma.

Pócza, Tímea; Sebestyén, Anna; Turányi, Eszter; Krenács, Tibor; Márk, Ágnes; Sticz TB; Jakab, Zsuzsanna; Hauser, Péter (2014)

As mammalian Target of Rapamycin (mTOR) plays role in protein synthesis and metabolism, mTOR pathway activation is involved in the pathogenesis of several types of tumors. Our aim was to elucidate its role in medulloblastoma ...
Rapamycin can restore the negative regulatory function of transforming growth factor beta 1 in high grade lymphomas

Sebestyén, Anna; Márk, Ágnes; Hajdu, Melinda; Nagy, Noémi; Molnár A; Végső, Gyula; Barna, Gábor; Kopper, László (2015)
Revisiting CB1 Receptor as Drug Target in Human Melanoma

Kenessey, István; Bánky, Balázs; Márk, Ágnes; Varga N,; Tóvári, József; Ladányi, Andrea; Rásó, Erzsébet; Tímár, József (2012)

Previous studies have indicated the antitumoral effect of human melanocytes, human melanoma cell lines expressing CB1 receptor (CB1), and of the peritumoral administration of endocannabinoids. In the present study, we ...

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tallózása szerző szerint "Márk, Ágnes"

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