tallózása szerző szerint "Pirker, Christine"

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The thiosemicarbazone Me2NNMe2 induces paraptosis by disrupting the ER thiol redox homeostasis based on protein disulfide isomerase inhibition

Hager, Sonja; Korbula, Katharina; Bielec, Björn; Grusch, Michael; Pirker, Christine; Schosserer, Markus; Liendl, Lisa; Lang, Magdalena; Grillari, Johannes; Nowikovsky, Karin; Pape, Veronika; Mohr, Thomas; Szakács, Gergely; Keppler, Bernhard K.; Berger, Walter; Kowol, Christian R.; Heffeter, Petra (2018)

Due to their high biological activity, thiosemicarbazones have been developed for treatment of diverse diseases, including cancer, resulting in multiple clinical trials especially of the lead compound Triapine. During the ...
Trabectedin is active against malignant pleural mesothelioma cell and xenograft models and synergizes with chemotherapy and bcl-2 inhibition in vitro

Hoda, Mir A; Pirker, Christine; Dong, Yawen; Schelch, Karin; Heffeter, Petra; Kushtrim, Kryeziu; Sushilla, van Schoonhoven; Thomas, Klikovits; László, Viktória; Rózsás, Anita; Ozsvár, Judit; Walter, Klepetko; Döme, Balázs; Michael, Grusch; Hegedűs, Balázs; Walter, Berger (2016)

Malignant pleural mesothelioma (MPM) is characterized by widespread resistance to systemic therapy. Trabectedin is an antineoplastic agent targeting both the malignant cells and the tumor microenvironment which has been ...

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