tallózása szerző szerint "Pirker C"

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Aggressiveness of human melanoma xenograft models is promoted by aneuploidy-driven gene expression deregulation.

Mathieu V; Pirker C; Schmidt WM; Spiegl-Kreinecker S; Lotsch D; Heffeter P; Hegedűs, Balázs; Grusch M; Kiss R; Berger W (2012)

Melanoma is a devastating skin cancer characterized by distinct biological subtypes. Besides frequent mutations in growth- and survival-promoting genes like BRAF and NRAS, melanomas additionally harbor complex non-random ...
Epigenetic down-regulation of integrin alpha7 increases migratory potential and confers poor prognosis in malignant pleural mesothelioma

Laszlo V; Hoda MA; Garay, Tamás; Pirker C; Ghanim B; Klikovits T; Dong YW; Rózsás, Anita; Kenessey, István; Szirtes, Ildikó; Grusch M; Jakopovic M; Samarzija M; Brcic L; Kern I; Rozman A; Popper H; Zochbauer-Muller S; Heller G; Altenberger C; Ziegler B; Klepetko W; Berger W; Döme, Balázs; Hegedűs, Balázs (2015)

Malignant pleural mesothelioma (MPM) is a devastating malignancy characterized by invasive growth and rapid recurrence. The identification and inhibition of molecular components leading to this migratory and invasive ...
FGF2 and EGF induce epithelial-mesenchymal transition in malignant pleural mesothelioma cells via a MAPKinase/MMP1 signal

Schelch K; Wagner C; Hager S; Pirker C; Siess K; Döme, Balázs; Hegedűs, Balázs (2018)

Malignant pleural mesothelioma (MPM), an aggressive malignancy affecting pleural surfaces, occurs in three main histological subtypes. The epithelioid and sarcomatoid subtypes are characterized by cuboid and fibroblastoid ...
Fibroblast growth factor receptor inhibition is active against mesothelioma and synergizes with radio- and chemotherapy

Schelch K; Hoda MA; Klikovits T; Munzker J; Ghanim B; Wagner C; Garay, Tamás; Laszlo, Viktoria; Setinek U; Döme, Balázs; Filipits M; Pirker C; Heffeter P; Selzer E; Tóvári, József; Török, Szilvia; Kenessey, István; Holzmann K; Grasl-Kraupp B; Marian B; Klepetko W; Berger W; Hegedűs, Balázs; Grusch M (2014)

RATIONALE: Malignant pleural mesothelioma is an aggressive malignancy characterized by frequent resistance to chemo- and radiotherapy, poor outcome, and limited therapeutic options. Fibroblast growth factors (FGFs) and ...
Intrathoracic solitary fibrous tumor - an international multicenter study on clinical outcome and novel circulating biomarkers

Ghanim B; Hess S; Bertoglio P; Celik A; Bas A; Oberndorfer F; Melfi F; Mussi A; Klepetko W; Pirker C; Berger W; Harmati I; Farkas A; Jan Ankersmit H; Döme, Balázs; Fillinger J; Aigner C; Hegedűs, Balázs; Rényi-Vámos, Ferenc István; Lang, György (2017)

Intrathoracic solitary fibrous tumor (SFT) is a rare disease. Radical resection is the standard of care. However, estimating prognosis and planning follow-up and treatment strategies remains challenging. Data were ...
Sensitivity of Melanoma Cells to EGFR and FGFR Activation but Not Inhibition is Influenced by Oncogenic BRAF and NRAS Mutations

Garay, Tamás; Molnár, Eszter; Juhasz E; Laszlo V; Barbai, Tamás; Dobos J; Schelch K; Pirker C; Grusch M; Berger W; Tímár, József; Hegedűs, Balázs (2015)

BRAF and NRAS are the two most frequent oncogenic driver mutations in melanoma and are pivotal components of both the EGF and FGF signaling network. Accordingly, we investigated the effect of BRAF and NRAS oncogenic mutation ...

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tallózása szerző szerint "Pirker C"

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