tallózása szerző szerint "Riba, Pál"

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A new potent analgesic agent with reduced liability to produce morphine tolerance

Király, Kornél P; Caputi FF,; Hanuska, Adrienn; Kató, Erzsébet; balogh, Mihály; Köles, László; Riba, Pál; Hosztafi, Sándor; Ferdinandy, Péter; Fürst, Zsuzsanna; Al-Khrasani, Mahmoud (2015)

The therapeutic use of opioids is limited by the development of tolerance to the analgesic effect and the cellular and molecular mechanisms underlying this phenomenon are still not completely understood. For this reason ...
Characterization of phenolic compounds and antinociceptive activity of Sempervivum tectorum L. leaf juice.

Alberti, Ágnes; Béni, Szabolcs; Lackó, Erzsébet; Riba, Pál; Al-Khrasani, Mahmoud; Kéry, Ágnes (2012)

Sempervivum tectorum L. (houseleek) leaf juice has been known as a traditional herbal remedy. The aim of the present study was the chemical characterization of its phenolic compounds and to develop quantitation methods for ...
Efficacy-based perspective to overcome reduced opioid analgesia of advanced painful diabetic neuropathy in rats

Balogh, Mihály; Zádor, Ferenc; Zádori, S. Zoltán; Shaqura, Mohammed; Király, Kornél P.; Mohammadzadeh, Amir; Varga, K. Bence; Lázár, Bernadette; Mousa, A. Shaaban; Hosztafi, Sándor; Riba, Pál; Benyhe, Sándor; Gyires, Klára; Schäfer, Michael; Fürst, Susanna; Al-Khrasani, Mahmoud (2019)

Reduction of the opioid analgesia in diabetic neuropathic pain (DNP) results from mu-opioid receptor (MOR) reserve reduction. Herein, we examined the antinociceptive and antiallodynic actions of a novel opioid agonist ...
New morphine analogues produce peripheral antinociception within a certain dose range of their systemic administration

Lackó, Erzsébet; Riba, Pál; Giricz, Zoltán; Váradi, András; Cornic L; Balogh, Mihály; Király, Kornél P; Csekő, Kata; Hosztafi, Sándor; Zádori, Zoltán Sándor; Helyes, Zsuzsanna; Ferdinandy, Péter; Fürst, Zsuzsanna; Al-Khrasani, Mahmoud (2016)

Growing data support the peripheral opioid antinociceptive effect, particularly, in inflammatory pain models. Here, we examined the antinociceptive effects of the subcutaneously (s.c.) administered, recently synthesized ...
Peripheral antinociceptive efficacy and potency of a novel opioid compound 14-O-MeM6SU in comparison to known peptide and non-peptide opioid agonists in a rat model of inflammatory pain

Khalefa BI; Mousa SA; Shaqura M; Lackó, Erzsébet; Hosztafi, Sándor; Riba, Pál; Ferdinandy, Péter; Fürst, Zsuzsanna; Al-Khrasani, Mahmoud (2013)

This study compared the peripheral analgesic effects of a novel opioid agonist 14-O-methylmorphine-6-O-sulfate (14-O-MeM6SU), to that of non-peptide (morphine, fentanyl) and peptide opioid agonists (Met-enkephalin; met-ENK ...
Similarity and dissimilarity in antinociceptive effects of dipeptidyl-peptidase 4 inhibitors, Diprotin A and vildagliptin in rat inflammatory pain models following spinal administration.

Balogh, Mihály; Varga, Bence Kálmán; Karádi, Dávid Árpád; Riba, Pál; Puskár, Zita; Kozsurek, Márk; Al-Khrasani, Mahmoud; Király, Kornél (2019)

Dipeptidyl-peptidase 4 (DPP4) enzyme is involved in the degradation of many biologically active peptides including opioids. Its role in pain transmission is poorly elucidated. Recently we reported on the spinal antihyperalgesic ...

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tallózása szerző szerint "Riba, Pál"

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