tallózása szerző szerint "Sukumar S"

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Activation of tumor suppressor LKB1 by honokiol abrogates cancer stem-like phenotype in breast cancer via inhibition of oncogenic Stat3

Sengupta S; Nagalingam A; Muniraj N; Bonner MY; Mistriotis P; Afthinos A; Kuppusamy P; Lanoue D; Cho S; Korangath P; Shriver M; Begum A; Merino VF; Huang CY; Arbiser JL; Matsui W; Győrffy, Balázs; Konstantopoulos K; Sukumar S; Marignani PA; Saxena NK; Sharma D (2017)

Tumor suppressor and upstream master kinase Liver kinase B1 (LKB1) plays a significant role in suppressing cancer growth and metastatic progression. We show that low-LKB1 expression significantly correlates with poor ...
Guidelines for the selection of functional assays to evaluate the hallmarks of cancer

Menyhart, Otilia; Harami-Papp H; Sukumar S; Schäfer R; Magnani L; de Barrios O; Győrffy, Balázs (2016)

The hallmarks of cancer capture the most essential phenotypic characteristics of malignant transformation and progression. Although numerous factors involved in this multi-step process are still unknown to date, an ...
HOXC10 expression supports the development of chemotherapy resistance by fine tuning DNA repair in breast cancer cells

Sadik H; Korangath P; Nguyen NK; Győrffy, Balázs; Kumar R; Hedayati M; Teo WW; Park S; Panday H; Munoz TG; Menyhart, Otilia; Shah N; Pandita RK; Chang JC; DeWeese T; Chang HY; Pandita TK; Sukumar S (2016)

Development of drug resistance is a major factor limiting the continued success of cancer chemotherapy. To overcome drug resistance, understanding the underlying mechanism(s) is essential. We found that HOXC10 is overexpressed ...
Induction of cell cycle arrest and inflammatory genes by combined treatment with epigenetic, differentiating, and chemotherapeutic agents in triple-negative breast cancer

Merino VF; Cho S; Nguyen N; Sadik H; Narayan A; Talbot C Jr; Cope L; Zhou XC; Zhang Z; Győrffy, Balázs; Sukumar S (2018)

Background: A combination of entinostat, all-trans retinoic acid, and doxorubicin (EAD) induces cell death and differentiation and causes significant regression of xenografts of triple-negative breast cancer (TNBC). Methods: ...

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tallózása szerző szerint "Sukumar S"

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tallózása szerző szerint "Sukumar S"

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