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MTMT-ben szereplő publikációk tallózása szerző szerint "Győrffy, Balázs"

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ABCC2 (MRP2, cMOAT) localized in the nuclear envelope of breast carcinoma cells correlates with poor clinical outcome

Maciejczyk A; Jagoda E; Wysocka T; Matkowski R; Győrffy, Balázs; Lage H; Surowiak P (2012)
Aberrant DNA methylation impacts gene expression and prognosis in breast cancer subtypes

Győrffy, Balázs; Bottai G; Fleischer T; Munkácsy, Gyöngyi; Budczies J; Paladini L; Boressen-Dale AL; Kristensen VN; Santarpia L (2016)
Acid ceramidase is associated with an improved prognosis in both DCIS and invasive breast cancer

Sänger N; Ruckhäberle E; Győrffy, Balázs; Engels K; Heinrich T; Fehm T; Graf A; Holtrich U; Becker S; Karn T (2015)
A Comprehensive Outline of Trastuzumab Resistance Biomarkers in HER2 Overexpressing Breast Cancer

Menyhart, Otilia; Santarpia L; Győrffy, Balázs (2015)

The introduction of trastuzumab for anti-HER2 therapy dramatically changed the clinical outcome for HER2 (ERBB2, neu) positive breast cancer patients. Today, patients eligible for trastuzumab are selected using HER2 ...
A comprehensive overview of targeted therapy in metastatic renal cell carcinoma

Mihály, Zsuzsanna; Sztupinszki, Zsófia; Surowiak P; Győrffy, Balázs (2012)

Chemotherapy and immunotherapy failed to deliver decisive results in the systemic treatment of metastatic renal cell carcinoma. Agents representing the current standards operate on members of the RAS signal transduction ...
Activation of Farnesoid X Receptor impairs the tumor-promoting function of breast cancer-associated fibroblasts

Barone I; Vircillo V; Giordano C; Gelsomino L; Győrffy, Balázs; Tarallo R; Rinaldi A; Bruno G; Caruso A; Romeo F; Bonofiglio D; Andò S; Catalano S (2018)

Cancer-associated Fibroblasts (CAFs), the principal components of tumor microenvironment, play multiple role in breast cancer progression. We have previously shown an oncosuppressive role of the nuclear Farnesoid X Receptor ...
Activation of tumor suppressor LKB1 by honokiol abrogates cancer stem-like phenotype in breast cancer via inhibition of oncogenic Stat3

Sengupta S; Nagalingam A; Muniraj N; Bonner MY; Mistriotis P; Afthinos A; Kuppusamy P; Lanoue D; Cho S; Korangath P; Shriver M; Begum A; Merino VF; Huang CY; Arbiser JL; Matsui W; Győrffy, Balázs; Konstantopoulos K; Sukumar S; Marignani PA; Saxena NK; Sharma D (2017)

Tumor suppressor and upstream master kinase Liver kinase B1 (LKB1) plays a significant role in suppressing cancer growth and metastatic progression. We show that low-LKB1 expression significantly correlates with poor ...
ADIPOQ/adiponectin induces cytotoxic autophagy in breast cancer cells through STK11/LKB1-mediated activation of the AMPK-ULK1 axis

Chung SJ; Nagaraju GP; Nagalingam A; Muniraj N; Kuppusamy P; Walker A; Woo J; Győrffy, Balázs; Gabrielson E; Saxena NK; Sharma D (2017)

ADIPOQ/adiponectin, an adipocytokine secreted by adipocytes in the breast tumor microenvironment, negatively regulates cancer cell growth hence increased levels of ADIPOQ/adiponectin are associated with decreased breast ...
Afatinib restrains K-RAS-driven lung tumorigenesis

Moll HP; Pranz K; Musteanu M; Grabner B; Hruschka N; Mohrherr J; Aigner P; Stiedl P; Brcic L; Laszlo, Viktoria; Schramek D; Moriggl R; Eferl R; Moldvay, Judit; Dezső, Katalin; Lopez-Casas PP; Stoiber D; Hidalgo M; Penninger J; Sibilia M; Győrffy, Balázs; Barbacid M; Döme, Balázs; Popper H; Casanova E (2018)

On the basis of clinical trials using first-generation epidermal growth factor receptor (EGFR) tyrosine kinase inhibitors (TKIs), it became a doctrine that V-Ki-ras2 Kirsten rat sarcoma viral oncogene homolog (K-RAS) ...
A functional interplay between ZNF217 and Estrogen Receptor alpha exists in luminal breast cancers

Nguyen NT; Vendrell JA; Poulard C; Győrffy, Balázs; Goddard-Léon S; Biècheg I; Corbo L; Le Romancer M; Bachelot T; Treilleux I; Cohen PA (2014)
A genome-wide approach to link genotype to clinical outcome by utilizing next generation sequencing and gene chip data of 6,697 breast cancer patients

Pongor, Lőrinc; Kormos, Máté; Hatzis C; Pusztai L; Szabó, András; Győrffy, Balázs (2015)

BACKGROUND: The use of somatic mutations for predicting clinical outcome is difficult because a mutation can indirectly influence the function of many genes, and also because clinical follow-up is sparse in the relatively ...
Alterations in SCAI Expression during Cell Plasticity, Fibrosis and Cancer

Gasparics, Ákos; Kökény, Gábor; Fintha, Attila; Bencs R; Mózes, Miklós; Ágoston EI; Buday, Anna; Ivics, Zoltán; Hamar, Péter; Győrffy, Balázs; Rosivall, László; Sebe, Attila (2018)
A meta-analysis of gene expression-based biomarkers predicting outcome after tamoxifen treatment in breast cancer

Mihály, Zsuzsanna; Kormos, Máté; Lanczky A; Dank, Magdolna; Budczies J; Szász, Attila Marcell; Győrffy, Balázs (2013)

To date, three molecular markers (ER, PR, and CYP2D6) have been used in clinical setting to predict the benefit of the anti-estrogen tamoxifen therapy. Our aim was to validate new biomarker candidates predicting response ...
A metasztatizáló világossejtes veserák prognózisának előrejelzése microarray vizsgálatok alapján

Mihály, Zsuzsanna; Sztupinszki, Zsófia; Szendrői, Attila; Szűcs, Miklós; Nyirády, Péter; Győrffy, Balázs (2013)
Analysis of gene expression profiles in melanoma cells with acquired resistance against antineoplastic drugs

Győrffy, Balázs; Serra V; Materna V; Schafer R; Dietel M; Schadendorf D; Lage H (2006)

Resistance to various antineoplastic agents is common in the clinical management of malignant melanoma. The biological mechanisms conferring these different drug-resistant phenotypes are still unclear. To identify ...
An online survival analysis tool to rapidly assess the effect of 22,277 genes on breast cancer prognosis using microarray data of 1,809 patients

Győrffy, Balázs; Lánczky A; Eklund AC; Denkert C; Budczies J; Li Q; Szállási Z (2010)

Validating prognostic or predictive candidate genes in appropriately powered breast cancer cohorts are of utmost interest. Our aim was to develop an online tool to draw survival plots, which can be used to assess the ...
A novel role for the interleukin-1 receptor axis in resistance to anti-EGFR therapy

Gelfo V; Mazzeschi M; Grilli G; Lindzen M; Santi S; D’uva G; Győrffy, Balázs; Ardizzoni A; Yarden Y; Lauriola M (2018)
APOBEC3B-Mediated Cytidine Deamination Is Required for Estrogen Receptor Action in Breast Cancer

Periyasamy M; Patel H; Lai CF; Nguyen VT; Nevedomskaya E; Harrod A; Russell R; Remenyi J; Ochocka AM; Thomas RS; Fuller-Pace F; Győrffy, Balázs; Caldas C; Navaratnam N; Carroll JS; Zwart W; Coombes RC; Magnani L; Buluwela L; Ali S (2015)

Estrogen receptor alpha (ERalpha) is the key transcriptional driver in a large proportion of breast cancers. We report that APOBEC3B (A3B) is required for regulation of gene expression by ER and acts by causing C-to-U ...
A prognostic gene expression index in ovarian cancer - validation across different independent data sets

Denkert C; Budczies J; Darb-Esfahani S; Győrffy, Balázs; Sehouli J; Könsgen D; Zeillinger R; Weichert W; Noske A; Buckendahl AC; Müller BM; Sietel M; Lage H (2009)

Ovarian carcinoma has the highest mortality rate among gynaecological malignancies. In this project, we investigated the hypothesis that molecular markers are able to predict outcome of ovarian cancer independently of ...
Arginyltransferase suppresses cell tumorigenic potential and inversely correlates with metastases in human cancers

Rai, R; Zhang, F; Colavita, K; Leu, NA; Kurosaka, S; Kumar, A; Birnbaum, MD; Győrffy, Balázs (2016)

Arginylation is an emerging post-translational modification mediated by arginyltransferase (ATE1) that is essential for mammalian embryogenesis and regulation of the cytoskeleton. Here, we discovered that Ate1-knockout ...

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MTMT-ben szereplő publikációk tallózása szerző szerint "Győrffy, Balázs"

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MTMT-ben szereplő publikációk tallózása szerző szerint "Győrffy, Balázs"

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