Van Bergen, Nicole J; Guo, Yiran; Rankin, Julia; Paczia, Nicole; Becker-Kettern, Julia; Kremer, Laura S; Pyle, Angela; Conrotte, Jean-François; Ellaway, Carolyn; Procopis, Peter; Prelog, Kristina; Homfray, Tessa; Baptista, Júlia; Baple, Emma; Wakeling, Matthew; Massey, Sean; Kay, Daniel P; Shukla, Anju; Girisha, Katta M; Lewis, Leslie E S; Santra, Saikat; Power, Rachel; Daubeney, Piers; Montoya, Julio; Ruiz-Pesini, Eduardo; Kovács-Nagy, Réka; Pritsch, Martin; Ahting, Uwe; Thorburn, David R; Prokisch, Holger; Taylor, Robert W; Christodoulou, John; Linster, Carole L; Ellard, Sian; Hakonarson, Hakon
(2019)
Physical stress, including high temperatures, may damage the central metabolic nicotinamide nucleotide cofactors [NAD(P)H], generating toxic derivatives [NAD(P)HX]. The highly conserved enzyme NAD(P)HX dehydratase (NAXD) ...