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dc.contributor.author Yanez-Mo M
dc.contributor.author Siljander PR
dc.contributor.author Andreu Z
dc.contributor.author Zavec AB
dc.contributor.author Borras FE
dc.contributor.author Buzás, Edit Irén
dc.contributor.author Buzás, Krisztina
dc.contributor.author Casal E
dc.contributor.author Cappello F
dc.contributor.author Carvalho J
dc.contributor.author Colas E
dc.contributor.author Cordeiro-da Silva A
dc.contributor.author Fais S
dc.contributor.author Falcon-Perez JM
dc.contributor.author Ghobrial IM
dc.contributor.author Giebel B
dc.contributor.author Gimona M
dc.contributor.author Graner M
dc.contributor.author Gursel I
dc.contributor.author Gursel M
dc.contributor.author Heegaard NH
dc.contributor.author Hendrix A
dc.contributor.author Kierulf P
dc.contributor.author Kokubun K
dc.contributor.author Kosanovic M
dc.contributor.author Kralj-Iglic V
dc.contributor.author Kramer-Albers EM
dc.contributor.author Laitinen S
dc.contributor.author Lasser C
dc.contributor.author Lener T
dc.contributor.author Ligeti, Erzsébet
dc.contributor.author Line A
dc.contributor.author Lipps G
dc.contributor.author Llorente A
dc.contributor.author Lotvall J
dc.contributor.author Mancek-Keber M
dc.contributor.author Marcilla A
dc.contributor.author Mittelbrunn M
dc.contributor.author Nazarenko I
dc.contributor.author Nolte-'t Hoen EN
dc.contributor.author Nyman TA
dc.contributor.author O'Driscoll L
dc.contributor.author Olivan M
dc.contributor.author Oliveira C
dc.contributor.author Pállinger, Éva
dc.contributor.author Del Portillo HA
dc.contributor.author Reventos J
dc.contributor.author Rigau M
dc.contributor.author Rohde E
dc.contributor.author Sammar M
dc.contributor.author Sanchez-Madrid F
dc.contributor.author Santarem N
dc.contributor.author Schallmoser K
dc.contributor.author Ostenfeld MS
dc.contributor.author Stoorvogel W
dc.contributor.author Stukelj R
dc.contributor.author Van der Grein SG
dc.contributor.author Vasconcelos MH
dc.contributor.author Wauben MH
dc.contributor.author De Wever O
dc.date.accessioned 2016-07-14T08:15:00Z
dc.date.available 2016-07-14T08:15:00Z
dc.date.issued 2015
dc.identifier.citation pagination=27066; journalVolume=4; journalTitle=JOURNAL OF EXTRACELLULAR VESICLES;
dc.identifier.uri http://repo.lib.semmelweis.hu//handle/123456789/2671
dc.identifier.uri doi:10.3402/jev.v4.27066
dc.description.abstract In the past decade, extracellular vesicles (EVs) have been recognized as potent vehicles of intercellular communication, both in prokaryotes and eukaryotes. This is due to their capacity to transfer proteins, lipids and nucleic acids, thereby influencing various physiological and pathological functions of both recipient and parent cells. While intensive investigation has targeted the role of EVs in different pathological processes, for example, in cancer and autoimmune diseases, the EV-mediated maintenance of homeostasis and the regulation of physiological functions have remained less explored. Here, we provide a comprehensive overview of the current understanding of the physiological roles of EVs, which has been written by crowd-sourcing, drawing on the unique EV expertise of academia-based scientists, clinicians and industry based in 27 European countries, the United States and Australia. This review is intended to be of relevance to both researchers already working on EV biology and to newcomers who will encounter this universal cell biological system. Therefore, here we address the molecular contents and functions of EVs in various tissues and body fluids from cell systems to organs. We also review the physiological mechanisms of EVs in bacteria, lower eukaryotes and plants to highlight the functional uniformity of this emerging communication system.
dc.title Biological properties of extracellular vesicles and their physiological functions
dc.type Journal Article
dc.date.updated 2015-11-24T15:01:59Z
dc.language.rfc3066 en
dc.identifier.mtmt 2930099
dc.identifier.pubmed 25979354
dc.contributor.department SE/AOK/I/Élettani Intézet
dc.contributor.department SE/AOK/I/Genetikai, Sejt- és Immunbiológiai Intézet
dc.contributor.institution Semmelweis Egyetem
dc.mtmt.swordnote Yanez-Mo M and Siljander PR authors have contributed equally. The rest of the authors are listed in alphabetical order.


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