dc.contributor.author |
Bödör, Csaba |
|
dc.contributor.author |
Reiniger, Lilla |
|
dc.date.accessioned |
2016-10-12T13:06:00Z |
|
dc.date.available |
2016-10-12T13:06:00Z |
|
dc.date.issued |
2016 |
|
dc.identifier |
84960130671 |
|
dc.identifier.citation |
pagination=109-127;
journalVolume=35;
journalIssueNumber=1;
journalTitle=CANCER AND METASTASIS REVIEWS; |
|
dc.identifier.uri |
http://repo.lib.semmelweis.hu//handle/123456789/3698 |
|
dc.identifier.uri |
doi:10.1007/s10555-016-9608-2 |
|
dc.description.abstract |
The recent application of next-generation sequencing technologies lead to significant improvements in our understanding of genetic underpinnings of non-Hodgkin lymphomas with identification of an unexpectedly high number of novel mutation targets across the different B-cell lymphoma entities. These recently discovered molecular lesions are expected to have a major impact on development of novel biomarkers and targeted therapies as well as patient stratification based on the underlying genetic profile. This review will cover the major discoveries in B-cell lymphomas using next-generation sequencing technologies over the last few years, highlighting alterations associated with relapse and progression of these diseases. |
|
dc.relation.ispartof |
urn:issn:0167-7659 |
|
dc.title |
Catalog of genetic progression of human cancers: non-Hodgkin lymphoma. |
|
dc.type |
Journal Article |
|
dc.date.updated |
2016-10-03T11:20:59Z |
|
dc.language.rfc3066 |
en |
|
dc.identifier.mtmt |
3052076 |
|
dc.identifier.pubmed |
26957091 |
|
dc.contributor.department |
SE/AOK/I/I. Sz. Patológiai és Kísérleti Rákkutató Intézet |
|
dc.contributor.department |
SE/AOK/I/ISZPKRI/MTA-SE Lendület Molekuláris Onkohematológia Kutatócsoport |
|
dc.contributor.institution |
Semmelweis Egyetem |
|