Genetic polymorphisms of vascular endothelial growth factor and angiopoietin 2 in retinopathy of prematurity

dc.contributor.author	Bányász, Ilona
dc.contributor.author	Bokodi, Géza
dc.contributor.author	Vannay, Ádám
dc.contributor.author	Szebeni, Beáta
dc.contributor.author	Treszl, András
dc.contributor.author	Vásárhelyi, Barna
dc.contributor.author	Tulassay, Tivadar
dc.contributor.author	Szabó, András
dc.date.accessioned	2017-08-29T09:40:18Z
dc.date.available	2017-08-29T09:40:18Z
dc.date.issued	2006
dc.identifier	33746858957
dc.identifier.citation	pagination=685-690; journalVolume=31; journalIssueNumber=7-8; journalTitle=CURRENT EYE RESEARCH;
dc.identifier.uri	http://repo.lib.semmelweis.hu//handle/123456789/4248
dc.identifier.uri	doi:10.1080/02713680600801123
dc.description.abstract	Angiogenic factors such as vascular endothelial growth factor (VEGF) and angiopoietin 2 (Ang2) contribute to development of retinopathy of prematurity (ROP). We aimed to test whether polymorphisms of these factors are associated with ROP. VEGF(-2578) and Ang2(-35) polymorphisms were analyzed with PCR-RFLP method in 200 preterm infants without ROP or with ROP stages 1-5. Our results suggest that there is no association between carrier state of VEGF(-2578) and Ang2(-35) and risk of ROP in preterm infants. The prevalence of VEGF(-2578) "A allele was lower in preterm boys with severe ROP (stages 4-5) than in those without or with mild ROP (stages 1-3).
dc.relation.ispartof	urn:issn:0271-3683
dc.title	Genetic polymorphisms of vascular endothelial growth factor and angiopoietin 2 in retinopathy of prematurity
dc.type	Journal Article
dc.date.updated	2017-04-04T11:12:48Z
dc.language.rfc3066	en
dc.identifier.mtmt	155417
dc.identifier.wos	000239452200014
dc.identifier.pubmed	16877277
dc.contributor.department	SE/AOK/K/ISZGYK/MTA-SE Gyermekgyógyászati és Nephrológiai Kutatócsoport
dc.contributor.department	SE/AOK/K/I. Sz. Gyermekgyógyászati Klinika
dc.contributor.institution	Semmelweis Egyetem