dc.contributor.author |
Hajosi-Kalcakosz S |
|
dc.contributor.author |
Vincze E |
|
dc.contributor.author |
Dezső, Katalin |
|
dc.contributor.author |
Paku, Sándor |
|
dc.contributor.author |
Rókusz, András |
|
dc.contributor.author |
Sápi, Zoltán |
|
dc.contributor.author |
Tóth, Erika |
|
dc.contributor.author |
Nagy, Péter |
|
dc.date.accessioned |
2018-06-11T09:15:44Z |
|
dc.date.available |
2018-06-11T09:15:44Z |
|
dc.date.issued |
2015 |
|
dc.identifier |
84941629733 |
|
dc.identifier.citation |
pagination=163, pages: 5;
journalVolume=10;
journalTitle=DIAGNOSTIC PATHOLOGY; |
|
dc.identifier.uri |
http://repo.lib.semmelweis.hu//handle/123456789/5541 |
|
dc.identifier.uri |
doi:10.1186/s13000-015-0392-z |
|
dc.description.abstract |
BACKGROUND: The immunohistochemical detection of Enhancer of zeste homologue 2 (EZH2) proved to be a useful tool to recognize the malignant nature of tumors in a wide variety of neoplasms. The histological diagnostics of salivary gland tumors is a challenging task, and a reliable marker of malignancy would be extremely helpful. METHODS: EZH2 expression was investigated in 54 malignant and 40 benign salivary gland tumors of various histological types by standard immunohistochemistry. RESULTS: The majority (n = 52) of the malignant tumors stained positively, while all the investigated benign tumors were negative for EZH2. CONCLUSIONS: EZH2 expression in salivary gland tumors, similarly to the tumors of other organs is not characteristic for any tumor type, but is a solid marker of the malignant nature of the tumors. |
|
dc.relation.ispartof |
urn:issn:1746-1596 |
|
dc.title |
EZH2 is a sensitive marker of malignancy in salivary gland tumors |
|
dc.type |
Journal Article |
|
dc.date.updated |
2018-06-06T12:17:42Z |
|
dc.language.rfc3066 |
en |
|
dc.identifier.mtmt |
3020701 |
|
dc.identifier.wos |
000361281600002 |
|
dc.identifier.pubmed |
26377323 |
|
dc.contributor.department |
SE/AOK/I/I. Sz. Patológiai és Kísérleti Rákkutató Intézet |
|
dc.contributor.department |
SE/AOK/I/IISZPI/MTA-SE Molekuláris Onkológia Kutatócsoport |
|
dc.contributor.institution |
Semmelweis Egyetem |
|