Signs of subclinical atherosclerosis in asymptomatic patients at increased risk of type 2 diabetes mellitus

Signs of subclinical atherosclerosis in asymptomatic patients at increased risk of type 2 diabetes mellitus

Kiss LZ; Bagyura, Zsolt; Vadas R; Polgár, Lívia; Lux, Árpád; Édes, Eszter; Szenczi, Orsolya; Soós, Pál; Szelid, Zsolt László; Becker, Dávid; Jermendy G; Merkely, Béla Péter

Folyóiratcikk

JOURNAL OF DIABETES AND ITS COMPLICATIONS vol.:31, issue.:8, p.:1293-1298.

ISSN: 1056-8727

URI: http://repo.lib.semmelweis.hu//handle/123456789/5769
http://dx.doi.org/10.1016/j.jdiacomp.2017.05.007

MTMT azonosító: 3235402

WoS ID: 000406081200010

PubMed ID: 28576484

Megjelenés éve: 2017

Kivonat:

AIMS: We aimed to study carotid intima media thickness (CIMT) in asymptomatic patients with an increased risk of type 2 diabetes mellitus (T2DM) and in a pre-diabetic state. METHODS: Diabetes risk assessment was performed in 2420 participants in a voluntary screening program between 2011 and 2013. The risk of T2DM was estimated by the Findrisc scoring system (FR). A FR>/=12 was considered as increased risk. HbA1c% between 5.7 and 6.4% signified a pre-diabetic state. Carotid duplex scan was performed and CIMT above 0.9 mm was regarded as pathological. Patients with T2DM or a history of cardiovascular disease were excluded. RESULTS: Overall 1475 subjects were included. Four groups were compared: "control" (normal HbA1c, FR. CONCLUSIONS: Evaluation of Findrisc score and HbA1c at population level may facilitate early recognition of subclinical vascular complications even in the pre-diabetic state.

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