Show simple item record Decmann, Ábel Perge, Pál Nagy, Zoltán Butz, Henriett Patócs, Attila Balázs Igaz, Péter 2018-08-09T08:26:20Z 2018-08-09T08:26:20Z 2017
dc.identifier 85016475789
dc.identifier.citation pagination=483-490; journalVolume=158; journalIssueNumber=13; journalTitle=ORVOSI HETILAP;
dc.identifier.uri doi:10.1556/650.2017.30708
dc.description.abstract MicroRNAs (miRNA, miR) are short - 19-25 nucleotide long - single stranded (in their mature form), non-coding RNA molecules that regulate gene expression mostly at the posttranscriptional level. microRNAs are involved in the regulation of various physiological processes such as cell differentiation and proliferation, development, haematopoesis, cell death, while their aberrant expression is observed in numerous diseases, like autoimmune disorders, inflammations, vascular diseases or tumorigenesis. microRNAs are expressed in a tissue specific fashion. Beyond their appearance in tissues, they can be found in body fluids as well. microRNAs are present in blood, mother milk, semen, saliva, urine, etc. MicroRNAs in body fluids, especially the blood-borne circulating microRNAs can be exploited as minimally invasive biomarkers of tumor diagnosis. The number of endocrine tumor-associated circulating microRNA alterations is relatively low, mostly described for papillary thyroid cancer, adrenocortical cancer, ovarian and neuroendocrine tumors. As the histological diagnosis including the establishment of malignancy of some of these neoplasms is difficult, studies on circulating microRNAs might have great perspectives. Orv. Hetil., 2017, 158(13), 483-490.
dc.relation.ispartof urn:issn:0030-6002
dc.title Keringő mikroRNS-ek az endokrin daganatok diagnosztikájában [Circulating microRNAs in the diagnostics of endocrine neoplasms]
dc.type Journal Article 2018-07-16T10:51:51Z
dc.language.rfc3066 hu
dc.identifier.mtmt 3207163
dc.identifier.wos 000397860200001
dc.identifier.pubmed 28347154
dc.contributor.department SE/AOK/K/IISZBK/MTA-SE Lendület Örökletes Endokrin Daganatok Kutatócsoport
dc.contributor.department SE/AOK/K/II. Sz. Belgyógyászati Klinika
dc.contributor.institution Semmelweis Egyetem
dc.mtmt.swordnote Orvosi Hetilap Markusovszky Lajos Díjjal kitüntetett közlemény

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