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dc.contributor.author Fancsovits, Péter
dc.contributor.author Urbancsek, János Attila
dc.contributor.author Fónyad, László
dc.contributor.author Sebestyén, Anna
dc.contributor.author Csorba G
dc.contributor.author Lehner, Ádám
dc.contributor.author Kaszás, Zita
dc.contributor.author Rigó, János
dc.contributor.author Bokor, Attila
dc.date.accessioned 2018-10-01T09:21:07Z
dc.date.available 2018-10-01T09:21:07Z
dc.date.issued 2016
dc.identifier 85006041885
dc.identifier.citation pagination=1947-1954; journalVolume=157; journalIssueNumber=49; journalTitle=ORVOSI HETILAP;
dc.identifier.uri http://repo.lib.semmelweis.hu//handle/123456789/5862
dc.identifier.uri doi:10.1556/650.2016.30582
dc.description.abstract INTRODUCTION: The oncological treatment may damage ovarian function. To prevent this, it is possible to cryopreserve the ovarian tissue, and to keep the samples for long-term storage. The frozen-thawed tissue could be retransplanted after chemo- or radiotherapy. AIM: The aim of our study was to examine the effect of cryopreservation on the viability of ovarian tissue. METHOD: We analyzed the survival of frozen-thawed donated ovarian tissues. The quality of the follicles and hormone production in fresh and frozen-thawed samples were compared. RESULTS: Histological analysis showed that the number of viable follicles was reduced by 23% in the frozen-thawed samples. However, viable follicles still presented in post thawing ovarian tissues. Maximal estradiol production in frozen-thawed tissues was 908 pg/ml and hormone production was similar to the control tissues. The maximal progesterone production was 1.95 ng/ml post thawing, but these values were lower than the progesterone production of fresh tissues. CONCLUSIONS: The method of ovarian cryopreservation used in our laboratory was able preserve the viability of follicles in frozen-thawed ovarian tissues. Orv. Hetil., 2016, 157(49), 1947-1954.
dc.relation.ispartof urn:issn:0030-6002
dc.title Kezdeti tapasztalataink a petefészekszövet-fagyasztás bevezetésével. [First attempts in the introduction of cryopreservation of ovarian tissues]
dc.type Journal Article
dc.date.updated 2018-07-16T13:31:52Z
dc.language.rfc3066 hu
dc.identifier.mtmt 3151734
dc.identifier.wos 000389882600002
dc.identifier.pubmed 27917673
dc.contributor.department SE/AOK/K/I. Sz. Szülészeti és Nőgyógyászati Klinika
dc.contributor.department SE/AOK/I/I. Sz. Patológiai és Kísérleti Rákkutató Intézet
dc.contributor.institution Semmelweis Egyetem


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