Kivonat:
Magnetic and fluorescent hydroxyapatite nanoparticles were synthesised using Al(OH)(3)-stabilised MnFe2O4 or Fe3O4 nanoparticles as precursors. They were readily and efficiently radiolabelled with F-18. Bisphosphonate polyethylene glycol polymers were utilised to endow the nanoparticles with excellent colloidal stability in water and to incorporate cyclam for high affinity labelling with Cu-64.