dc.contributor.author |
Mészáros, Szilvia |
|
dc.contributor.author |
Tabák, Ádám |
|
dc.contributor.author |
Horváth, Csaba |
|
dc.contributor.author |
Szathmári, Miklós |
|
dc.contributor.author |
Laszlo, JF |
|
dc.date.accessioned |
2020-05-20T09:31:56Z |
|
dc.date.available |
2020-05-20T09:31:56Z |
|
dc.date.issued |
2013 |
|
dc.identifier |
84885114915 |
|
dc.identifier.citation |
journalVolume=89;journalIssueNumber=10;journalTitle=INTERNATIONAL JOURNAL OF RADIATION BIOLOGY;pagerange=877-885;journalAbbreviatedTitle=INT J RADIAT BIOL; |
|
dc.identifier.uri |
http://repo.lib.semmelweis.hu//handle/123456789/7015 |
|
dc.identifier.uri |
doi:10.3109/09553002.2013.800249 |
|
dc.description.abstract |
Purpose: Static magnetic field (SMF) could improve pain sensation and bone turnover. In a single-center randomized double-blind placebo-controlled study we investigated the effects of SMF exposure on subjective pain and bone turnover. Materials and methods: Postmenopausal osteoporotic women (aged 50-70 years) with bone deformity and back pain were randomized to 10 weekly visits of 30-min SMF (n = 6) or treatment with non-magnetized pads (n = 5) on the back. Primary and secondary outcomes were changes in pain sensation on a visual analogue scale (VAS) during each visit and over 10 weeks, respectively. Tertiary outcomes were changes in osteocalcin and beta-crosslaps. SMF was inhomogeneous with 192 millitesla peak-to-peak value by 19 tesla/meter gradient of the magnetic flux density at 3 mm. Results: Participants randomized to sham had higher VAS at baseline (mean difference: 2.8, 95% confidence interval (CI) 0.47-5.2 cm). Both SMF and sham similarly reduced short term pain (sham-SMF: 0.59, 95% CI - 0.31-1.49 cm, p = 0.195). VAS did not change in SMF, while it decreased in the sham group (between-group difference 0.27, 95% CI 0.04-0.50 cm/visit). Bone turnover markers remained stable. Conclusions: SMF as used in this investigation is not recommended for pain relief in postmenopausal women with vertebral deformity. The finding on long-term pain relief may relate to unbalanced randomization. |
|
dc.format.extent |
877-885 |
|
dc.title |
Influence of local exposure to static magnetic field on pain perception and bone turnover of osteoporotic patients with vertebral deformity - a randomized controlled trial |
|
dc.type |
Journal Article |
|
dc.date.updated |
2019-05-13T15:47:42Z |
|
dc.language.rfc3066 |
en |
|
dc.rights.holder |
NULL |
|
dc.identifier.mtmt |
2364465 |
|
dc.identifier.wos |
000325358500013 |
|
dc.identifier.pubmed |
23627714 |
|
dc.contributor.institution |
I. Sz. Belgyógyászati Klinika |
|