dc.contributor.author |
Nekkaa, Imane |
|
dc.contributor.author |
Bogdán, Dóra |
|
dc.contributor.author |
Gáti, Tamás |
|
dc.contributor.author |
Béni, Szabolcs |
|
dc.contributor.author |
Juhász, Tünde |
|
dc.contributor.author |
Palkó, Márta |
|
dc.contributor.author |
Paragi, Gábor |
|
dc.contributor.author |
Tóth, Gábor K. |
|
dc.contributor.author |
Fülöp, Ferenc |
|
dc.contributor.author |
Mándity, István M. |
|
dc.date.accessioned |
2019-08-26T15:50:34Z |
|
dc.date.available |
2019-08-26T15:50:34Z |
|
dc.date.issued |
2019 |
|
dc.identifier |
85062612654 |
|
dc.identifier.citation |
journalVolume=55;journalIssueNumber=21;journalTitle=CHEMICAL COMMUNICATIONS;pagerange=3061-3064;journalAbbreviatedTitle=CHEM COMMUN; |
|
dc.identifier.uri |
http://repo.lib.semmelweis.hu//handle/123456789/7434 |
|
dc.identifier.uri |
doi:10.1039/C8CC10147G |
|
dc.description.abstract |
Enantiodiscriminative helix formation was observed for beta-peptide H14 helices. This observation is caused by the synperiplanar orientation of H-O atoms which is more unfavorable than those for H-H interaction. The 1,2 H-O interaction leads to the destruction of the helical structure. The introduction of a double C-C bond in the backbone rules out helix formation. |
|
dc.format.extent |
3061-3064 |
|
dc.title |
Flow-chemistry enabled efficient synthesis of β-peptides: backbone topology vs. helix formation |
|
dc.type |
Journal Article |
|
dc.date.updated |
2019-08-10T08:05:12Z |
|
dc.language.rfc3066 |
en |
|
dc.rights.holder |
NULL |
|
dc.identifier.mtmt |
30535263 |
|
dc.identifier.wos |
000460731900033 |
|
dc.identifier.pubmed |
30720807 |
|
dc.contributor.department |
SE/GYTK/Farmakognózia Intézet |
|
dc.contributor.department |
SE/GYTK/Szerves Vegytani Intézet |
|
dc.contributor.institution |
Semmelweis Egyetem |
|
dc.mtmt.swordnote |
Funding Agency and Grant Number: Hungarian Research Foundation (OTKA) [K 115731]; Janos Bolyai Research Scholarship of the Hungarian Academy of Sciences; Bolyai + New National Excellence Program of the Ministry of Human Capacities [UNKP-18-4-SE-121]; [GINOP-2.3.2-15-2016-00014]; [GINOP-2.3.2-15-2016-00034]
Funding text: We are grateful to the Hungarian Research Foundation (OTKA No. K 115731). The financial support of the GINOP-2.3.2-15-2016-00014 and GINOP-2.3.2-15-2016-00034 projects are acknowledged. This work was partially supported by the Janos Bolyai Research Scholarship of the Hungarian Academy of Sciences and by the Bolyai + New National Excellence Program (grant number: UNKP-18-4-SE-121) of the Ministry of Human Capacities (S. Beni). |
|