dc.description.abstract |
Neutrophils are the most abundant circulating leukocytes, being the first line of defence against bacterial and fungal infections. However, neutrophils also contribute to tissue damage during various autoimmune and inflammatory diseases, and play important roles in cancer progression. The intimate but complex involvement of neutrophils in various diseases makes them exciting targets for therapeutic intervention but also necessitates differentiation of beneficial responses from potentially detrimental side effects. A variety of approaches to therapeutically target neutrophils have emerged, including strategies to enhance, inhibit or restore neutrophil function, with several agents entering clinical trials. However, challenges and controversies in the field remain. © 2020, Springer Nature Limited. |
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dc.mtmt.swordnote |
Export Date: 4 February 2020
CODEN: NRDDA
Correspondence Address: Németh, T.; Department of Physiology, Semmelweis University School of MedicineHungary; email: nemeth.tamas@med.semmelweis-univ.hu
Funding details: 777357
Funding details: VEKOP-2.3.2-16-2016-00002, K-NVKP_16-1-2016-0152956, KKP 129954
Funding details: Deutsche Forschungsgemeinschaft, DFG, SFB 914
Funding text 1: The authors apologize to the authors of numerous outstanding publications that had to be omitted due to space limitations. This work was supported by the Hungarian National Agency for Research, Development and Innovation (K-NVKP_16-1-2016-0152956, VEKOP-2.3.2-16-2016-00002 and KKP 129954 to A.M.), the European Union’s Horizon 2020 IMI2 programme (RTCure project; grant no. 777357 to A.M.) and the Deutsche Forschungsgemeinschaft (SFB 914 projects B01 and Z03, grant no. SP621/5-1 to M.S.).
Export Date: 5 February 2020
CODEN: NRDDA
Correspondence Address: Németh, T.; Department of Physiology, Semmelweis University School of MedicineHungary; email: nemeth.tamas@med.semmelweis-univ.hu
Funding details: 777357
Funding details: VEKOP-2.3.2-16-2016-00002, K-NVKP_16-1-2016-0152956, KKP 129954
Funding details: Deutsche Forschungsgemeinschaft, DFG, SFB 914
Funding text 1: The authors apologize to the authors of numerous outstanding publications that had to be omitted due to space limitations. This work was supported by the Hungarian National Agency for Research, Development and Innovation (K-NVKP_16-1-2016-0152956, VEKOP-2.3.2-16-2016-00002 and KKP 129954 to A.M.), the European Union’s Horizon 2020 IMI2 programme (RTCure project; grant no. 777357 to A.M.) and the Deutsche Forschungsgemeinschaft (SFB 914 projects B01 and Z03, grant no. SP621/5-1 to M.S.).
Export Date: 10 February 2020
CODEN: NRDDA
Correspondence Address: Németh, T.; Department of Physiology, Semmelweis University School of MedicineHungary; email: nemeth.tamas@med.semmelweis-univ.hu
Funding details: 777357
Funding details: VEKOP-2.3.2-16-2016-00002, K-NVKP_16-1-2016-0152956, KKP 129954
Funding details: Deutsche Forschungsgemeinschaft, DFG, SFB 914
Funding text 1: The authors apologize to the authors of numerous outstanding publications that had to be omitted due to space limitations. This work was supported by the Hungarian National Agency for Research, Development and Innovation (K-NVKP_16-1-2016-0152956, VEKOP-2.3.2-16-2016-00002 and KKP 129954 to A.M.), the European Union’s Horizon 2020 IMI2 programme (RTCure project; grant no. 777357 to A.M.) and the Deutsche Forschungsgemeinschaft (SFB 914 projects B01 and Z03, grant no. SP621/5-1 to M.S.). |
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