Generation of iPSC lines from peripheral blood mononuclear cells of identical twins both suffering from type 2 diabetes mellitus and one of them additionally diagnosed with atherosclerosis

dc.contributor.author	Szabó, Eszter
dc.contributor.author	Reé, Dóra
dc.contributor.author	Jezsó, Bálint
dc.contributor.author	Vincze, Katalin
dc.contributor.author	Földes, Gábor
dc.contributor.author	Molnár, Andrea Ágnes
dc.contributor.author	Réthelyi, János
dc.contributor.author	Apáti, Ágota
dc.date.accessioned	2021-06-21T06:23:16Z
dc.date.available	2021-06-21T06:23:16Z
dc.date.issued	2020
dc.identifier	85093654297
dc.identifier.citation	journalVolume=49;pagination=102051, pages: 4;journalTitle=STEM CELL RESEARCH;journalAbbreviatedTitle=STEM CELL RES;
dc.identifier.uri	http://repo.lib.semmelweis.hu//handle/123456789/8554
dc.identifier.uri	doi:10.1016/j.scr.2020.102051
dc.description.abstract	Here we describe the generation of induced pluripotent stem cell (iPSC) lines from peripheral blood samples of identical twin sisters with type 2 diabetes mellitus (DM2). Two clonal lines from each patient (HU-DM2-A-1, HU-DM2-A-2 and HU-DM2-B-1, HU-DM2-B-2) were established via Sendai viral reprograming of peripheral blood mononuclear cells, and characterized to confirm pluripotency and genetic integrity. The established iPSC lines can help to investigate DM2 related cellular phenotypes and provide a model system for drug testing. © 2020 The Authors
dc.relation.ispartof	urn:issn:1873-5061
dc.title	Generation of iPSC lines from peripheral blood mononuclear cells of identical twins both suffering from type 2 diabetes mellitus and one of them additionally diagnosed with atherosclerosis
dc.type	Journal Article
dc.date.updated	2020-12-07T11:46:17Z
dc.language.rfc3066	en
dc.rights.holder	NULL
dc.identifier.mtmt	31663099
dc.contributor.department	SE/AOK/K/VAROSMAJOR_SZÍVÉRGYÓGY/Kardiológia Központ - Kardiológiai Tanszék
dc.contributor.department	SE/AOK/K/Pszichiátriai és Pszichoterápiás Klinika
dc.contributor.department	SE/AOK/K/PPK/MTA-SE-NAP B Molekuláris pszichiátriai és in vitro betegségmodellezési kutatócsoport
dc.contributor.institution	Semmelweis Egyetem