tallózása szerző szerint "Laszlo, Viktoria"

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  • Afatinib restrains K-RAS-driven lung tumorigenesis 
    Moll HP; Pranz K; Musteanu M; Grabner B; Hruschka N; Mohrherr J; Aigner P; Stiedl P; Brcic L; Laszlo, Viktoria; Schramek D; Moriggl R; Eferl R; Moldvay, Judit; Dezső, Katalin; Lopez-Casas PP; Stoiber D; Hidalgo M; Penninger J; Sibilia M; Győrffy, Balázs; Barbacid M; Döme, Balázs; Popper H; Casanova E (2018)
    On the basis of clinical trials using first-generation epidermal growth factor receptor (EGFR) tyrosine kinase inhibitors (TKIs), it became a doctrine that V-Ki-ras2 Kirsten rat sarcoma viral oncogene homolog (K-RAS) ...
  • A New Mechanism for Pillar Formation during Tumor-Induced Intussusceptive Angiogenesis 
    Paku, Sándor; Dezső, Katalin; Bugyik, Edina; Tóvári, József; Tímár, József; Nagy, Péter; Laszlo, Viktoria; Klepetko W; Döme, Balázs (2011)
    One of the hallmarks of intussusceptive angiogenesis is the development of intraluminal connective tissue pillars. The exact mechanism of pillar formation has not yet been elucidated. By using electron and confocal microscopy, ...
  • Apelin promotes lymphangiogenesis and lymph node metastasis 
    Berta, Judit; Hoda MA; Laszlo, Viktoria; Rozsas A; Garay, Tamás; Torok S; Grusch M; Berger W; Paku, Sándor; Rényi-Vámos, Ferenc István; Masri B; Tóvári, József; Groger M; Klepetko W; Hegedűs, Balázs; Döme, Balázs (2014)
    Whereas the role of the G-protein-coupled APJ receptor and its ligand, apelin, in angiogenesis has been well documented, the ability of the apelin/APJ system to induce lymphangiogenesis and lymphatic metastasis has been ...
  • Cell migration or cytokinesis and proliferation? - revisiting the "go or grow" hypothesis in cancer cells in vitro. 
    Garay, Tamás; Juhasz E; Molnár, Eszter; Eisenbauer M; Czirók, András; Dekan B; Laszlo, Viktoria; Hoda MA; Döme, Balázs; Tímár, József; Klepetko W; Berger W; Hegedűs, Balázs (2013)
    The mortality of patients with solid tumors is mostly due to metastasis that relies on the interplay between migration and proliferation. The "go or grow" hypothesis postulates that migration and proliferation spatiotemporally ...
  • Development of arterial blood supply in experimental liver metastases 
    Dezső, Katalin; Bugyik, Edina; Papp, Veronika; Laszlo, Viktoria; Döme, Balázs; Tóvári, József; Tímár, József; Nagy, Péter; Paku, Sándor (2009)
  • Distinct epidemiology and clinical consequence of classic versus rare EGFR mutations in lung adenocarcinoma. 
    Lohinai, Zoltán; Hoda MA; Fábián, Katalin; Ostoros, Gyula; Rásó, Erzsébet; Barbai, Tamás; Tímár, József; Kovalszky, Ilona; Cserepes, Tamás Mihály; Laszlo, Viktoria; Grusch M; Berger W; Klepetko W; Moldvay, Judit; Döme, Balázs; Hegedűs, Balázs (2015)
    INTRODUCTION:: While classic sensitizing mutations of epidermal growth factor receptor (EGFR) are positive predictive markers for EGFR tyrosine kinase inhibitors (TKIs) in lung adenocarcinoma, there are rare EGFR mutations ...
  • Encephalitis and GABAB receptor antibodies: novel findings in a new case series of 20 patients 
    Hoftberger R; Titulaer MJ; Sabater L; Döme, Balázs; Rozsas A,; Hegedűs, Balázs; Hoda MA; Laszlo, Viktoria; Ankersmit HJ; Harms L; Boyero S; de Felipe A; Saiz A; Dalmau J; Graus F (2013)
    OBJECTIVE: To report the clinical features of 20 newly diagnosed patients with GABAB receptor (GABABR) antibodies and determine the frequency of associated tumors and concurrent neuronal autoantibodies. METHODS: Clinical ...
  • Erythropoietin receptor expression is a potential prognostic factor in human lung adenocarcinoma 
    Rozsas A; Berta, Judit; Rojko L; Horvath LZ; Keszthelyi M; Kenessey, István; Laszlo, Viktoria; Berger W; Grusch M; Hoda MA; Torok S; Klepetko W; Rényi-Vámos, Ferenc István; Hegedűs, Balázs; Döme, Balázs; Tóvári, József (2013)
    Recombinant human erythropoietins (rHuEPOs) are used to treat cancer-related anemia. Recent preclinical studies and clinical trials, however, have raised concerns about the potential tumor-promoting effects of these drugs. ...
  • Fibroblast growth factor receptor inhibition is active against mesothelioma and synergizes with radio- and chemotherapy 
    Schelch K; Hoda MA; Klikovits T; Munzker J; Ghanim B; Wagner C; Garay, Tamás; Laszlo, Viktoria; Setinek U; Döme, Balázs; Filipits M; Pirker C; Heffeter P; Selzer E; Tóvári, József; Török, Szilvia; Kenessey, István; Holzmann K; Grasl-Kraupp B; Marian B; Klepetko W; Berger W; Hegedűs, Balázs; Grusch M (2014)
    RATIONALE: Malignant pleural mesothelioma is an aggressive malignancy characterized by frequent resistance to chemo- and radiotherapy, poor outcome, and limited therapeutic options. Fibroblast growth factors (FGFs) and ...
  • Lack of Angiogenesis in Experimental Brain Metastases 
    Bugyik, Edina; Dezső, Katalin; Reiniger, Lilla; Laszlo, Viktoria; Tóvári, József; Tímár, József; Nagy, Péter; Klepetko W; Döme, Balázs; Paku, Sándor (2011)
    Angiogenesis is believed to be essential for the growth of metastatic tumors in the brain. We analyzed the vascularization of tumors formed by 4 epithelial cell lines (C38, ZR75, HT25, and H1650) and a fibrosarcoma (HT1080) ...
  • Localization of sunitinib, its metabolites and its target receptors in tumour bearing mice: a MALDI mass spectrometry imaging study 
    Török, Szilvia; Vegvari A; Rezeli M; Fehniger TE; Tóvári, József; Paku, Sándor; Laszlo, Viktoria; Hegedűs, Balázs; Rózsás, Anita; Döme, Balázs; Marko-Varga G (2015)
    BACKGROUND AND PURPOSE: The clinical impact of antiangiogenic agents remains controversial. Therefore, elucidating the pharmacological properties of these compounds is a pivotal issue. EXPERIMENTAL APPROACH: In our study, ...
  • Mechanism of tumour vascularisation in experimental lung metastases 
    Szabó, Vanessza; Bugyik, Edina; Dezső, Katalin; Ecker N; Nagy, Péter; Tímár, József; Tóvári, József; Laszlo, Viktoria; Bridgeman VL; Wan E; Frentzas S; Vermeulen PB; Reynolds AR; Döme, Balázs; Paku, Sándor (2015)
    The appearance of lung metastases is associated with poor outcome and the management of patients with secondary pulmonary tumours remains a clinical challenge. We examined the vascularisation process of lung metastasis in ...
  • Suppression of activin A signals inhibits growth of malignant pleural mesothelioma cells 
    Hoda MA,; Munzker J,; Ghanim B,; Schelch K,; Klikovits T,; Laszlo, Viktoria; Sahin E; Bedeir A; Lackner A; Döme, Balázs; Setinek U; Filipits M; Eisenbauer M; Kenessey, István; Török Szilvia; Garay, Tamás; Hegedűs, Balázs; Catania A; Taghavi S; Klepetko W; Berger W; Grusch M (2012)
    Background:Activins control the growth of several tumour types including thoracic malignancies. In the present study, we investigated their expression and function in malignant pleural mesothelioma (MPM).Methods:The ...