tallózása szerző szerint "Varga, Zoltán"

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  • Acute hyperglycemia abolishes cardioprotection by remote ischemic perconditioning 
    Baranyai, Tamás; Nagy, Csilla Terézia; Koncsos, Gábor; Onódi, Zsófia; Karolyi-Szabo M; Makkos, András; Varga, Zoltán; Ferdinandy, Péter; Giricz, Zoltán (2015)
    BACKGROUND: Remote ischemic perconditioning (RIPerC) has a promising therapeutic insight to improve the prognosis of acute myocardial infarction. Chronic comorbidities such as diabetes are known to interfere with conditioning ...
  • Alternative Splicing of NOX4 in the Failing Human Heart 
    Varga, Zoltán; Pipicz, Márton; Baán, Júlia Aliz; Baranyai T; Koncsos, Gábor; Leszek P; Kusmierczyk M; Sanchez-Cabo F; Garcia-Pavia P; Brenner, Gábor; Giricz, Zoltán; Csont, Tamás Bálint; Mendler, Luca; Lara-Pezzi E; Pacher, Pál; Ferdinandy, Péter (2017)
    Increased oxidative stress is a major contributor to the development and progression of heart failure, however, our knowledge on the role of the distinct NADPH oxidase (NOX) isoenzymes, especially on NOX4 is controversial. ...
  • Analysis of necroptotic proteins in failing human hearts 
    Szobi A; Goncalvesova E; Varga, Zoltán; Leszek P; Kusmierczyk M; Hulman M; Kyselovic J; Ferdinandy, Péter; Adameova A (2017)
    BACKGROUND: Cell loss and subsequent deterioration of contractile function are hallmarks of chronic heart failure (HF). While apoptosis has been investigated as a participant in the progression of HF, it is unlikely that ...
  • Anti-diabetic effect of a preparation of vitamins, minerals and trace elements in diabetic rats: a gender difference 
    Sárközy, Márta; Fekete, Veronika; Szűcs, Gergő; Török, Szilvia; Szűcs, Csilla; Barkányi, Judit; Varga, Zoltán; Földesi, Imre; Csonka, Csaba; Kónya, Csaba; Csont, Tamás Bálint; Ferdinandy, Péter (2014)
    BACKGROUND: Although multivitamin products are widely used as dietary supplements to maintain health or as special medical food in certain diseases, the effects of these products were not investigated in diabetes mellitus, ...
  • Author Correction: MicroRNA interactome analysis predicts post-transcriptional regulation of ADRB2 and PPP3R1 in the hypercholesterolemic myocardium 
    Ágg, Bence; Baranyai, Tamás; Makkos, András; Veto, B; Faragó, Nóra; Zvara, Ágnes; Giricz, Zoltán; Veres, Dániel; Csermely, Péter; Arányi, Tamás; Puskás, László; Varga, Zoltán; Ferdinandy, Péter (2018)
  • Autophagosome formation is required for cardioprotection by chloramphenicol 
    Giricz, Zoltán; Varga, Zoltán; Koncsos, Gábor; Nagy, Csilla Terézia; Görbe, Anikó; Mentzer RM Jr; Gottlieb RA; Ferdinandy, Péter (2017)
    AIMS: Chloramphenicol (CAP), a broad spectrum antibiotic, was shown to protect the heart against ischemia/reperfusion (I/R) injury. CAP also induces autophagy, however, it is not known whether CAP-induced cardioprotection ...
  • Biorelevant polyanions stabilize fibrin against mechanical and proteolytic decomposition: Effects of polymer size and electric charge 
    Komorowicz, Erzsébet; Balázs, Nóra; Tanka-Salamon, Anna; Varga, Zoltán; Szabó, László; Bóta, Attila; Longstaff, Colin; Kolev, Krasimir (2020)
  • Cardiac Nitric Oxide Signalling in Metabolic Syndrome 
    Pechanova O; Varga, Zoltán; Cebova M; Giricz, Zoltán; Pacher, Pál; Ferdinandy, Péter (2015)
    It is well documented that metabolic syndrome (i.e. a group of risk factors, such as abdominal obesity, elevated blood pressure, elevated fasting plasma glucose, high serum triglycerides, and low cholesterol level in ...
  • Cardioprotection by gene therapy 
    Madonna R; Cadeddu C; Deidda M; Giricz, Zoltán; Madeddu C; Mele D; Monte I; Novo G; Pagliaro P; Pepe A; Spallarossa P; Tocchetti CG; Varga, Zoltán; Zito C; Geng YJ; Mercuro G; Ferdinandy, Péter (2015)
    Ischemic heart disease remains the leading cause of death worldwide. Ischemic pre-, post-, and remote conditionings trigger endogenous cardioprotection that renders the heart resistant to ischemic-reperfusion injury (IRI). ...
  • Cardioprotection by remote ischemic preconditioning of the rat heart is mediated by extracellular vesicles 
    Giricz, Zoltán; Varga, Zoltán; Baranyai, Tamás; Sipos, Péter; Pálóczi, Krisztina; Kittel, Ágnes; Buzás, Edit Irén; Ferdinandy, Péter (2014)
    Remote ischemic preconditioning (RIPC) of the heart is exerted by brief ischemic insults affected on a remote organ or a remote area of the heart before a sustained cardiac ischemia. To date, little is known about the ...
  • Cytoprotection by the NO-donor SNAP against ischemia/reoxygenation injury in mouse embryonic stem cell-derived cardiomyocytes 
    Görbe, Anikó; Varga, Zoltán; Pálóczi, János; S. Rungarunlert; N. Klincumhom; Pirity, Melinda; R. Madonna; T. Eschenhagen; Dinnyés, András; Csont, Tamás Bálint; Ferdinandy, Péter (2014)
    Embryonic stem cell (ESC)-derived cardiomyocytes are a promising cell source for the screening for potential cytoprotective molecules against ischemia/reperfusion injury, however, little is known on their behavior ...
  • Definition of hidden drug cardiotoxicity 
    Ferdinandy, Péter; Baczkó, István; Bencsik, Péter; Giricz, Zoltán; Görbe, Anikó; Pacher, Pál; Varga, Zoltán; Varró, András; Schulz, R (2019)
    Unexpected cardiac adverse effects are the leading causes of discontinuation of clinical trials and withdrawal of drugs from the market. Since the original observations in the mid-90s, it has been well established that ...
  • Development of Matrix Metalloproteinase-2 Inhibitors for Cardioprotection 
    Bencsik, Péter; Kupai, Krisztina; Görbe, Anikó; Kenyeres, Éva; Varga, Zoltán; Pálóczi, János; Gáspár, Renáta; Kovács László; Lutz Weber; Takács Ferenc; Hajdú, István; Fabó Gabriella; Cseh, Sándor; Barna, László; Csont, Tamás; Csonka, Csaba; Dormán, György; Ferdinandy, Péter (2018)
    The objective of our present study is to develop novel inhibitors for MMP-2 for acute cardioprotection. In a series of pilot studies, novel substituted carboxylic acid derivatives were synthesized based on imidazole and ...
  • Diastolic dysfunction in prediabetic male rats: role of mitochondrial oxidative stress 
    Koncsos, Gábor; Varga, Zoltán; Baranyai, Tamás; Boengler K; Rohrbach S; Li L; Schluter KD; Schreckenberg R; Radovits, Tamás; Oláh, Attila; Mátyás, Csaba; Lux, Árpád; Al-Khrasani, Mahmoud; Komlódi, Tímea; Bukosza, Éva Nóra; Máthé, Domokos; Deres, László; Bartekova M; Rajtik T; Adameova A; Szigeti, Krisztián; Hamar, Péter; Helyes, Zsuzsanna; Tretter, László; Pacher, Pál; Merkely, Béla Péter; Giricz, Zoltán; Schulz R; Ferdinandy, Péter (2016)
    Although incidence and prevalence of prediabetes are increasing, little is known on its cardiac effects. Therefore, our aim was to investigate the effect of prediabetes on cardiac function and to characterize parameters ...
  • Drug-induced mitochondrial dysfunction and cardiotoxicity 
    Varga, Zoltán; Ferdinandy, Péter; Liaudet L; Pacher, Pál (2015)
    Mitochondria has essential role in myocardial tissue homeostasis, thus deterioration in mitochondrial function eventually leads to cardiomyocyte and endothelial cell death and consequent cardiovascular dysfunction. Several ...
  • Evaluation of Brain Nuclear Medicine Imaging Tracers in a Murine Model of Sepsis-Associated Encephalopathy 
    Szollosi D; Hegedus N; Veres, Dániel; Futo I; Horvath I; Kovacs N; Martinecz, Bernadett; Dénes, Ádám; Seifert D; Bergmann R; Lebeda O; Varga, Zoltán; Kaleta Z; Szigeti, Krisztián; Máthé, Domokos (2018)
    PURPOSE: The purpose of this study was to evaluate a set of widely used nuclear medicine imaging agents as possible methods to study the early effects of systemic inflammation on the living brain in a mouse model of ...
  • Fibroblast-derived extracellular vesicles induce colorectal cancer progression by transmitting amphiregulin 
    Oszvald, Ádám; Szvicsek, Zsuzsanna; Pápai, Márton; Kelemen, Andrea; Varga, Zoltán; Tölgyes, Tamás; Dede, Kristóf; Bursics, Attila; Buzás, Edit Irén; Wiener, Zoltán (2020)
  • Fluorescent, Prussian Blue-Based Biocompatible Nanoparticle System for Multimodal Imaging Contrast 
    Forgách, László; Hegedűs, Nikolett; Horváth, Ildikó; Kiss, Bálint; Kovács, Noémi; Varga, Zoltán; Jakab, Géza; Kovács, Tibor; Padmanabhan, Parasuraman; Szigeti, Krisztián; Máthé, Domokos (2020)
  • Functional genomics of cardioprotection by ischemic conditioning and the influence of comorbid conditions: implications in target identification 
    Varga, Zoltán; Giricz, Zoltán; Bencsik, Péter; Rosalinda Madonna; Gyöngyösi Mariann; Rainer Schulz; Manuel Mayr; Thomas Thum; Puskás, László; Ferdinandy, Péter (2015)
    Ischemic heart disease including myocardial infarction is developing on the basis of several risk-factors and co-morbidities such as obesity, diabetes, hypertension, and hypercholesterolemia. Ischemic heart disease is the ...
  • Hypercholesterolemia downregulates autophagy in the rat heart 
    Giricz, Zoltán; Koncsos, Gábor; Tomáš Rajtík; Varga, Zoltán; Baranyai, Tamás; Csonka, Csaba; Adrián Szobi; Adriana Adameová; Roberta A Gottlieb; Ferdinandy, Péter (2017)
    Background: We have previously shown that efficiency of ischemic conditioning is diminished in hypercholesterolemia and that autophagy is necessary for cardioprotection. However, it is unknown whether isolated hypercholesterolemia ...