Show simple item record Schumann G Binder EB Holte A de Kloet ER Oedegaard KJ Robbins TW Walker-Tilley TR Bitter, István Brown VJ Buitelaar J Ciccocioppo R Cools R Escera C Fleischhacker W Flor H Frith CD Heinz A Johnsen E Kirschbaum C Klingberg T Lesch KP Lewis S Maier W Mann K Martinot JL Meyer-Lindenberg A Muller CP Muller WE Nutt DJ Persico A Perugi G Pessiglione M Preuss UW Roiser JP Rossini PM Rybakowski JK Sandi C Stephan KE Undurraga J Vieta E van der Wee N Wykes T Haro JM Wittchen HU 2015-02-05T13:45:10Z 2015-02-05T13:45:10Z 2014
dc.identifier 84892623734
dc.identifier.citation pagination=5-50; journalVolume=24; journalIssueNumber=1; journalTitle=EUROPEAN NEUROPSYCHOPHARMACOLOGY;
dc.identifier.uri doi:10.1016/j.euroneuro.2013.09.010
dc.description.abstract There is recognition that biomedical research into the causes of mental disorders and their treatment needs to adopt new approaches to research. Novel biomedical techniques have advanced our understanding of how the brain develops and is shaped by behaviour and environment. This has led to the advent of stratified medicine, which translates advances in basic research by targeting aetiological mechanisms underlying mental disorder. The resulting increase in diagnostic precision and targeted treatments may provide a window of opportunity to address the large public health burden, and individual suffering associated with mental disorders. While mental health and mental disorders have significant representation in the "health, demographic change and wellbeing" challenge identified in Horizon 2020, the framework programme for research and innovation of the European Commission (2014-2020), and in national funding agencies, clear advice on a potential strategy for mental health research investment is needed. The development of such a strategy is supported by the EC-funded "Roadmap for Mental Health Research" (ROAMER) which will provide recommendations for a European mental health research strategy integrating the areas of biomedicine, psychology, public health well being, research integration and structuring, and stakeholder participation. Leading experts on biomedical research on mental disorders have provided an assessment of the state of the art in core psychopathological domains, including arousal and stress regulation, affect, cognition social processes, comorbidity and pharmacotherapy. They have identified major advances and promising methods and pointed out gaps to be addressed in order to achieve the promise of a stratified medicine for mental disorders.
dc.relation.ispartof urn:issn:0924-977X
dc.title Stratified medicine for mental disorders.
dc.type Journal Article 2015-01-23T11:15:12Z
dc.language.rfc3066 en
dc.identifier.mtmt 2449000
dc.identifier.wos 000330816200002
dc.identifier.pubmed 24176673
dc.contributor.department SE/AOK/K/Pszichiátriai és Pszichoterápiás Klinika
dc.contributor.institution Semmelweis Egyetem

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