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dc.contributor.author Steinberg S
dc.contributor.author de Jong S
dc.contributor.author Mattheisen M
dc.contributor.author Costas J
dc.contributor.author Demontis D
dc.contributor.author Jamain S
dc.contributor.author Pietilainen OP
dc.contributor.author Lin K
dc.contributor.author Papiol S
dc.contributor.author Huttenlocher J
dc.contributor.author Sigurdsson E
dc.contributor.author Vassos E
dc.contributor.author Giegling I
dc.contributor.author Breuer R
dc.contributor.author Fraser G
dc.contributor.author Walker N
dc.contributor.author Melle I
dc.contributor.author Djurovic S
dc.contributor.author Agartz I
dc.contributor.author Tuulio-Henriksson A
dc.contributor.author Suvisaari J
dc.contributor.author Lonnqvist J
dc.contributor.author Paunio T
dc.contributor.author Olsen L
dc.contributor.author Hansen T
dc.contributor.author Ingason A
dc.contributor.author Pirinen M
dc.contributor.author Strengman E
dc.contributor.author Hougaard DM
dc.contributor.author Orntoft T
dc.contributor.author Didriksen M
dc.contributor.author Hollegaard MV
dc.contributor.author Nordentoft M
dc.contributor.author Abramova L
dc.contributor.author Kaleda V
dc.contributor.author Arrojo M
dc.contributor.author Sanjuan J
dc.contributor.author Arango C
dc.contributor.author Etain B
dc.contributor.author Bellivier F
dc.contributor.author Meary A
dc.contributor.author Schurhoff F
dc.contributor.author Szoke A
dc.contributor.author Ribolsi M
dc.contributor.author Magni V
dc.contributor.author Siracusano A
dc.contributor.author Sperling S
dc.contributor.author Rossner M
dc.contributor.author Christiansen C
dc.contributor.author Kiemeney LA
dc.contributor.author Franke B
dc.contributor.author van den Berg LH
dc.contributor.author Veldink J
dc.contributor.author Curran S
dc.contributor.author Bolton P
dc.contributor.author Poot M
dc.contributor.author Staal W
dc.contributor.author Rehnstrom K
dc.contributor.author Kilpinen H
dc.contributor.author Freitag CM
dc.contributor.author Meyer J
dc.contributor.author Magnusson P
dc.contributor.author Saemundsen E
dc.contributor.author Martsenkovsky I
dc.contributor.author Bikshaieva I
dc.contributor.author Martsenkovska I
dc.contributor.author Vashchenko O
dc.contributor.author Raleva M
dc.contributor.author Paketchieva K
dc.contributor.author Stefanovski B
dc.contributor.author Durmishi N
dc.contributor.author Pejovic Milovancevic M
dc.contributor.author Lecic Tosevski D
dc.contributor.author Silagadze T
dc.contributor.author Naneishvili N
dc.contributor.author Mikeladze N
dc.contributor.author Surguladze S
dc.contributor.author Vincent JB
dc.contributor.author Farmer A
dc.contributor.author Mitchell PB
dc.contributor.author Wright A
dc.contributor.author Schofield PR
dc.contributor.author Fullerton JM
dc.contributor.author Montgomery GW
dc.contributor.author Martin NG
dc.contributor.author Rubino IA
dc.contributor.author van Winkel R
dc.contributor.author Kenis G
dc.contributor.author De Hert M
dc.contributor.author Réthelyi, János
dc.contributor.author Bitter, István
dc.contributor.author Terenius L
dc.contributor.author Jonsson EG
dc.contributor.author Bakker S
dc.contributor.author van Os J
dc.contributor.author Jablensky A
dc.contributor.author Leboyer M
dc.contributor.author Bramon E
dc.contributor.author Powell J
dc.contributor.author Murray R
dc.contributor.author Corvin A
dc.contributor.author Gill M
dc.contributor.author Morris D
dc.contributor.author O'Neill FA
dc.contributor.author Kendler K
dc.contributor.author Riley B
dc.contributor.author Craddock N
dc.contributor.author Owen MJ
dc.contributor.author O'Donovan MC
dc.contributor.author Thorsteinsdottir U
dc.contributor.author Kong A
dc.contributor.author Ehrenreich H
dc.contributor.author Carracedo A
dc.contributor.author Golimbet V
dc.contributor.author Andreassen OA
dc.contributor.author Borglum AD
dc.contributor.author Mors O
dc.contributor.author Mortensen PB
dc.contributor.author Werge T
dc.contributor.author Ophoff RA
dc.contributor.author Nothen MM
dc.contributor.author Rietschel M
dc.contributor.author Cichon S
dc.contributor.author Ruggeri M
dc.contributor.author Tosato S
dc.contributor.author Palotie A
dc.contributor.author St Clair D
dc.contributor.author Rujescu D
dc.contributor.author Collier DA
dc.contributor.author Stefansson H
dc.contributor.author Stefansson K
dc.date.accessioned 2015-03-10T12:56:51Z
dc.date.available 2015-03-10T12:56:51Z
dc.date.issued 2014
dc.identifier 84891157599
dc.identifier.citation pagination=108-114; journalVolume=19; journalIssueNumber=1; journalTitle=MOLECULAR PSYCHIATRY;
dc.identifier.uri http://repo.lib.semmelweis.hu//handle/123456789/1214
dc.identifier.uri doi:10.1038/mp.2012.157
dc.description.abstract Epidemiological and genetic data support the notion that schizophrenia and bipolar disorder share genetic risk factors. In our previous genome-wide association study, meta-analysis and follow-up (totaling as many as 18 206 cases and 42 536 controls), we identified four loci showing genome-wide significant association with schizophrenia. Here we consider a mixed schizophrenia and bipolar disorder (psychosis) phenotype (addition of 7469 bipolar disorder cases, 1535 schizophrenia cases, 333 other psychosis cases, 808 unaffected family members and 46 160 controls). Combined analysis reveals a novel variant at 16p11.2 showing genome-wide significant association (rs4583255[T]; odds ratio=1.08; P=6.6 x 10(-11)). The new variant is located within a 593-kb region that substantially increases risk of psychosis when duplicated. In line with the association of the duplication with reduced body mass index (BMI), rs4583255[T] is also associated with lower BMI (P=0.0039 in the public GIANT consortium data set; P=0.00047 in 22 651 additional Icelanders).Molecular Psychiatry advance online publication, 20 November 2012; doi:10.1038/mp.2012.157.
dc.relation.ispartof urn:issn:1359-4184
dc.title Common variant at 16p11.2 conferring risk of psychosis
dc.type Journal Article
dc.date.updated 2015-01-23T11:18:24Z
dc.language.rfc3066 en
dc.identifier.mtmt 2134878
dc.identifier.wos 000328964700019
dc.identifier.pubmed 23164818
dc.contributor.department SE/AOK/K/Pszichiátriai és Pszichoterápiás Klinika
dc.contributor.institution Semmelweis Egyetem
dc.mtmt.swordnote CN GROUP CN Wellcome Trust Case Control Consortium 2


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