MTMT-ben szereplő publikációk tallózása szerző szerint "SE/AOK/I/Farmakológiai és Farmakoterápiás Intézet"

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  • Cardiac innervation in acute myocardial ischaemia/reperfusion injury and cardioprotection 
    Hausenloy, Derek J; Bøtker, Hans Erik; Ferdinandy, Péter; Heusch, Gerd; Ng, G André; Redington, Andrew; Garcia-Dorado, David; EU-CARDIOPROTECTION, COST Action (2019)
    Acute myocardial infarction (AMI) and the heart failure (HF) that often complicates this condition, are among the leading causes of death and disability worldwide. To reduce myocardial infarct (MI) size and prevent heart ...
  • Cardiac Nitric Oxide Signalling in Metabolic Syndrome 
    Pechanova O; Varga, Zoltán; Cebova M; Giricz, Zoltán; Pacher, Pál; Ferdinandy, Péter (2015)
    It is well documented that metabolic syndrome (i.e. a group of risk factors, such as abdominal obesity, elevated blood pressure, elevated fasting plasma glucose, high serum triglycerides, and low cholesterol level in ...
  • Cardioprotection by Farnesol: Role of the Mevalonate Pathway 
    Szűcs, Gergő; Murlasits, Zsolt; Török, Szilvia; Kocsis-Fodor, Gabriella; Pálóczi, János; Görbe, Anikó; Csont, Tamás Bálint; Csonka, Csaba; Ferdinandy, Péter (2013)
    Purpose: Farnesol is a key metabolite of the mevalonate pathway and known as an antioxidant. We examined whether farnesol treatment protects the ischemic heart. Methods: Male Wistar rats were treated orally with 0.2, 1, ...
  • Cardioprotection by gene therapy 
    Madonna R; Cadeddu C; Deidda M; Giricz, Zoltán; Madeddu C; Mele D; Monte I; Novo G; Pagliaro P; Pepe A; Spallarossa P; Tocchetti CG; Varga, Zoltán; Zito C; Geng YJ; Mercuro G; Ferdinandy, Péter (2015)
    Ischemic heart disease remains the leading cause of death worldwide. Ischemic pre-, post-, and remote conditionings trigger endogenous cardioprotection that renders the heart resistant to ischemic-reperfusion injury (IRI). ...
  • Cardioprotection by remote ischemic preconditioning of the rat heart is mediated by extracellular vesicles 
    Giricz, Zoltán; Varga, Zoltán; Baranyai, Tamás; Sipos, Péter; Pálóczi, Krisztina; Kittel, Ágnes; Buzás, Edit Irén; Ferdinandy, Péter (2014)
    Remote ischemic preconditioning (RIPC) of the heart is exerted by brief ischemic insults affected on a remote organ or a remote area of the heart before a sustained cardiac ischemia. To date, little is known about the ...
  • Catalyzing Transcriptomics Research in Cardiovascular Disease 
    Gomes, Clarissa Pedrosa da C; Ágg, Bence; Andova, Andrejaana; Arslan, Serdal; Baker, Andrew; Barteková, Monika; Beis, Dimitris; Betsou, Fay; Wettinger, Stephanie Bezzina; Bugarski, Branko; Condorelli, Gianluigi; Silva, Gustavo José Justo da; Danilin, Sabrina; Gonzalo-Calvo, David de; Buil, Alfonso; Carmo-Fonseca, Maria; Enguita, Francisco J; Felekkis, Kyriacos; Ferdinandy, Péter; Gyöngyösi, Mariann; Hackl, Matthias; Karaduzovic-Hadziabdic, Kanita; Hellemans, Jan; Heymans, Stephane; Hlavackova, Markéta; Hoydal, Morten Andre; Jankovic, Aleksandra; Jusic, Amela; Kardassis, Dimitris; Kerkelä, Risto; Kuster, Gabriela M; Lakkisto, Päivi; Leszek, Przemyslaw; Lustrek, Mitja; Maegdefessel, Lars; Martelli, Fabio; Novella, Susana; O'Brien, Timothy; Papaneophytou, Christos; Pedrazzini, Thierry; Pinet, Florence; Popescu, Octavian; Potočnjak, Ines; Robinson, Emma; Sasson, Shlomo; Scholz, Markus; Simionescu, Maya; Stoll, Monika; Varga, Zoltan V; Vinciguerra, Manlio; Xuereb, Angela; Yilmaz, Mehmet Birhan; Emanueli, Costanza; Devaux, Yvan; EU-CardioRNA Cost Action CA17129 (2019)
    Cardiovascular disease (CVD) remains the leading cause of death worldwide and, despite continuous advances, better diagnostic and prognostic tools, as well as therapy, are needed. The human transcriptome, which is the set ...
  • Chemically Modified Derivatives of the Activator Compound Cloxyquin Exert Inhibitory Effect on TRESK (K2P18.1) Background Potassium Channel. 
    Lengyel, Miklós; Erdélyi, Ferenc; Pergel, Enikő; Bálint-Polonka, Ágnes; Dobolyi, Alice; Bozsaki, Péter; Dux, Mária; Király, Kornél; Hegedűs, Tamás; Czirják, Gábor; Mátyus, Péter; Enyedi, Péter (2019)
    Cloxyquin has been reported as a specific activator of TRESK (K2P18.1, TWIK-related spinal cord K+ channel) background potassium channel. In this study, we have synthetized chemically modified analogues of cloxyquin and ...
  • Cholesterol-enriched diet inhibits cardioprotection by ATP-sensitive K+ channel activators cromakalim and diazoxide 
    Csonka, Csaba; Kupai, Krisztina; Bencsik, Péter; Görbe, Anikó; Pálóczi, János; Zvara, Ágnes; Puskás, László; Csont, Tamás Bálint; Ferdinandy, Péter (2014)
    It has been previously shown that hyperlipidemia interferes with cardioprotective mechanisms. Here we investigated the interaction of hyperlipidemia with cardioprotection induced by pharmacological activators of ATP-sensitive ...
  • Circulating blood cells and extracellular vesicles in acute cardioprotection 
    Davidson, Sean M; Andreadou, Ioanna; Barile, Lucio; Birnbaum, Yochai; Cabrera-Fuentes, Hector A; Cohen, Michael V; Downey, James M; Girao, Henrique; Pagliaro, Pasquale; Penna, Claudia; Pernow, John; Preissner, Klaus T; Ferdinandy, Péter; EU-CARDIOPROTECTION, COST Action (2019)
  • Co-Activation of Nuclear Factor-kappaB and Myocardin/Serum Response Factor Conveys the Hypertrophy Signal of High Insulin Levels in Cardiac Myoblasts 
    Madonna R; Geng YJ; Bolli R; Rokosh G; Ferdinandy, Péter; Patterson C; De Caterina R (2014)
    Background and Objective: Hyperinsulinemia contributes to cardiac hypertrophy and heart failure in patients with the metabolic syndrome and type 2 diabetes. Here high circulating levels of tumor necrosis factor (TNF)-alpha ...
  • Co-expression of glycosylated aquaporin-1 and transcription factor NFAT5 contributes to aortic stiffness in diabetic and atherosclerosis-prone mice 
    Madonna, Rosalinda; Doria, Vanessa; Görbe, Anikó; Cocco, Nino; Ferdinandy, Péter; Geng, Yong-Jian; Pierdomenico, Sante Donato; De Caterina, Raffaele (2020)
    Increased stiffness characterizes the early change in the arterial wall with subclinical atherosclerosis. Proteins inducing arterial stiffness in diabetes and hypercholesterolaemia are largely unknown. This study aimed at ...
  • Comparative lipophilicity of morphine derivatives 
    Kalász, Huba; Doležal R,; Tekes, Kornélia; Magyar, Kálmán; Csermely T,; Hosztafi, Sándor (2015)
  • Connexin 43 is an emerging therapeutic target in ischemia/reperfusion injury, cardioprotection and neuroprotection 
    Schulz R; Gorge PM; Görbe, Anikó; Ferdinandy, Péter; Lampe PD; Leybaert L (2015)
    Connexins are widely distributed proteins in the body that are crucially important for heart and brain function. Six connexin subunits form a connexon or hemichannel in the plasma membrane. Interactions between two ...
  • Connexins in Cardiovascular and Neurovascular Health and Disease: Pharmacological Implications 
    Leybaert L; Lampe PD; Dhein S; Kwak BR; Ferdinandy, Péter; Beyer EC; Laird DW; Naus CC; Green CR; Schulz R (2017)
    Connexins are ubiquitous channel forming proteins that assemble as plasma membrane hemichannels and as intercellular gap junction channels that directly connect cells. In the heart, gap junction channels electrically connect ...
  • Corrigendum to "European contribution to the study of ROS: A summary of the findings and prospects for the future from the COST action BM1203 (EU-ROS)" [Redox Biol. 13 (2017) 94-162] 
    Egea, J; Fabregat, I; Frapart, YM; Ghezzi, P; Görlach, A; Kietzmann, T; Kubaichuk, K; Knaus, UG; Lopez, MG; Olaso-Gonzalez, G; Petry, A; Schulz, R; Vina, J; Winyard, P; Abbas, K; Ademowo, OS; Afonso, CB; Andreadou, I; Antelmann, H; Antunes, F; Aslan, M; Bachschmid, MM; Barbosa, RM; Belousov, V; Berndt, C; Bernlohr, D; Bertrán, E; Bindoli, A; Bottari, SP; Brito, PM; Carrara, G; Casas, AI; Chatzi, A; Chondrogianni, N; Conrad, M; Cooke, MS; Costa, JG; Cuadrado, A; My-Chan, Dang P; De Smet, B; Debelec-Butuner, B; Dias, IHK; Dunn, JD; Edson, AJ; El, Assar M; El-Benna, J; Ferdinandy, Péter; Fernandes, AS; Fladmark, KE; Förstermann, U; Giniatullin, R; Giricz, Zoltán; Görbe, Anikó; Griffiths, H; Hampl, V; Hanf, A; Herget, J; Hernansanz-Agustín, P; Hillion, M; Huang, J; Ilikay, S; Jansen-Dürr, P; Jaquet, V; Joles, JA; Kalyanaraman, B; Kaminskyy, D; Karbaschi, M; Kleanthous, M; Klotz, LO; Korac, B; Korkmaz, KS; Koziel, R; Kračun, D; Krause, KH; Křen, V; Krieg, T; Laranjinha, J; Lazou, A; Li, H; Martínez-Ruiz, A; Matsui, R; McBean, GJ; Meredith, SP; Messens, J; Miguel, V; Mikhed, Y; Milisav, I; Milković, L; Miranda-Vizuete, A; Mojović, M; Monsalve, M; Mouthuy, PA; Mulvey, J; Münzel, T; Muzykantov, V; Nguyen, ITN; Oelze, M; Oliveira, NG; Palmeira, CM; Papaevgeniou, N; Pavićević, A; Pedre, B; Peyrot, F; Phylactides, M; Pircalabioru, GG; Pitt, AR; Poulsen, HE; Prieto, I; Rigobello, MP; Robledinos-Antón, N; Rodríguez-Mañas, L; Rolo, AP; Rousset, F; Ruskovska, T; Saraiva, N; Sasson, S; Schröder, K; Semen, K; Seredenina, T; Shakirzyanova, A; Smith, GL; Soldati, T; Sousa, BC; Spickett, CM; Stancic, A; Stasia, MJ; Steinbrenner, H; Stepanić, V; Steven, S; Tokatlidis, K; Tuncay, E; Turan, B; Ursini, F; Vacek, J; Vajnerova, O; Valentová, K; Van, Breusegem F; Varisli, L; Veal, EA; Yalçın, AS; Yelisyeyeva, O; Žarković, N; Zatloukalová, M; Zielonka, J; Touyz, RM; Papapetropoulos, A; Grune, T; Lamas, S; Schmidt, HHHW; Di Lisa, F; Daiber, A (2018)
  • Cyclothymic temperament rather than polarity is associated with hopelessness and suicidality in hospitalized patients with mood disorders. 
    Innamorati M,; Rihmer, Zoltán; Akiskal H,; Gonda, Xénia; Erbuto D, (2015)
  • Cytoprotection by the NO-donor SNAP against ischemia/reoxygenation injury in mouse embryonic stem cell-derived cardiomyocytes 
    Görbe, Anikó; Varga, Zoltán; Pálóczi, János; S. Rungarunlert; N. Klincumhom; Pirity, Melinda; R. Madonna; T. Eschenhagen; Dinnyés, András; Csont, Tamás Bálint; Ferdinandy, Péter (2014)
    Embryonic stem cell (ESC)-derived cardiomyocytes are a promising cell source for the screening for potential cytoprotective molecules against ischemia/reperfusion injury, however, little is known on their behavior ...
  • Decrease in REM latency and changes in sleep quality parallel serotonergic damage and recovery after MDMA: a longitudinal study over 180 days 
    Kirilly Eszter; Molnár Eszter; Balogh B; Kántor Sándor; Hansson SR; Palkovits Miklós; Bagdy György (2008)
    The recreational drug ecstasy [3,4-methylenedioxymethamphetamine (MDMA)], has been found to selectively damage brain serotonin neurons in experimental animals, and probably in human MDMA users, but detailed morphometric ...
  • Definition of hidden drug cardiotoxicity 
    Ferdinandy, Péter; Baczkó, István; Bencsik, Péter; Giricz, Zoltán; Görbe, Anikó; Pacher, Pál; Varga, Zoltán; Varró, András; Schulz, R (2019)
    Unexpected cardiac adverse effects are the leading causes of discontinuation of clinical trials and withdrawal of drugs from the market. Since the original observations in the mid-90s, it has been well established that ...
  • Development of Matrix Metalloproteinase-2 Inhibitors for Cardioprotection 
    Bencsik, Péter; Kupai, Krisztina; Görbe, Anikó; Kenyeres, Éva; Varga, Zoltán; Pálóczi, János; Gáspár, Renáta; Kovács László; Lutz Weber; Takács Ferenc; Hajdú, István; Fabó Gabriella; Cseh, Sándor; Barna, László; Csont, Tamás; Csonka, Csaba; Dormán, György; Ferdinandy, Péter (2018)
    The objective of our present study is to develop novel inhibitors for MMP-2 for acute cardioprotection. In a series of pilot studies, novel substituted carboxylic acid derivatives were synthesized based on imidazole and ...