MTMT-ben szereplő publikációk tallózása szerző szerint "Buday, László"

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  • Absence of the Tks4 Scaffold Protein Induces Epithelial-Mesenchymal Transition-Like Changes in Human Colon Cancer Cells 
    Szeder, Bálint; Tárnoki-Zách, Júlia; Lakatos, Dóra; Vas, Virág; Kudlik, Gyöngyi; Merő, Balázs; Koprivanacz, Kitti; Bányai, László; Hámori, Lilla; Róna, Gergely; Czirók, András; Füredi, András; Buday, László (2019)
    Epithelial to mesenchymal transition (EMT) is a multipurpose process involved in wound healing, development, and certain pathological processes, such as metastasis formation. The Tks4 scaffold protein has been implicated ...
  • Accumulation of the PX domain mutant Frank-ter Haar syndrome protein Tks4 in aggresomes 
    Ádám Csaba; Fekete, Anna; Bőgel, Gábor; Németh, Zsuzsanna; Tökési, Natália; Ovádi Judit; Liliom, Károly; Pesti, Szabolcs; Geiszt, Miklós; Buday, László (2015)
    BACKGROUND: Cells deploy quality control mechanisms to remove damaged or misfolded proteins. Recently, we have reported that a mutation (R43W) in the Frank-ter Haar syndrome protein Tks4 resulted in aberrant intracellular ...
  • Analysis of Tks4 Knockout Mice Suggests a Role for Tks4 in Adipose Tissue Homeostasis in the Context of Beigeing 
    Vas, Virág; Háhner, Tamás; Kudlik, Gyöngyi; Ernszt, Dávid; Kvell, Krisztián; Kuti, Dániel; Kovács, Krisztina J; Tóvári, József; Trexler, Mária; Merő, Balázs László; Szeder, Bálint; Koprivanacz, Kitti; Buday, László (2019)
    Obesity and adipocyte malfunction are related to and arise as consequences of disturbances in signaling pathways. Tyrosine kinase substrate with four Src homology 3 domains (Tks4) is a scaffold protein that establishes a ...
  • Dendritic spine morphology and memory formation depend on postsynaptic Caskin proteins 
    Bencsik, Norbert; Pusztai, Szilvia; Borbély, Sándor; Fekete, Anna; Dülk, Metta; Kis, Viktor; Pesti, Szabolcs; Vas, Virág; Szűcs, Attila; Buday, László; Schlett, Katalin (2019)
  • EGF regulates the interaction of Tks4 with Src through its SH2 and SH3 domains 
    Dülk, Metta; Szeder, Bálint; Glatz, Gábor; Mero B; Koprivanacz, Kitti; Kudlik, Gyöngyi; Vas, Virág; Sipeki, Szabolcs; Cserkaszky A; Radnai, László; Buday, László (2018)
    The non-receptor tyrosine kinase Src is a central component of the EGF signaling pathway. Our group recently showed that the Frank-ter Haar syndrome protein Tks4 (tyrosine kinase substrate with four Src homology 3 domains) ...
  • EGF regulates tyrosine phosphorylation and membrane-translocation of the scaffold protein Tks5 
    Fekete, Anna; Bőgel, Gábor; Pesti, Szabolcs; Péterfi, Zalán; Geiszt, Miklós; Buday, László (2013)
    Background: Tks5/FISH is a scaffold protein comprising of five SH3 domains and one PX domain. Tks5 is a substrate of the tyrosine kinase Src and is required for the organization of podosomes/invadopodia implicated in ...
  • Novel regulation of Ras proteins by direct tyrosine phosphorylation and dephosphorylation 
    Buday, László; Vas, Virág (2020)
    Somatic mutations in the RAS genes are frequent in human tumors, especially in pancreatic, colorectal, and non-small-cell lung cancers. Such mutations generally decrease the ability of Ras to hydrolyze GTP, maintaining the ...
  • Significance of the Tks4 scaffold protein in bone tissue homeostasis 
    Vas, Virág; Kovács, Tamás; Körmendi, Szandra Katalin; Bródy, Andrea; Kudlik, Gyöngyi; Szeder, Bálint; Mező, Diána; Kállai, Dóra; Koprivanacz, Kitti; Merő, Balázs László; Dülk, Metta; Tóvári, József; Vajdovich, Péter; Şenel, Ş Neslihan; Özcan, Ilknur; Helyes, Zsuzsanna; Dobó-Nagy, Csaba; Buday, László (2019)
    The main driver of osteoporosis is an imbalance between bone resorption and formation. The pathogenesis of osteoporosis has also been connected to genetic alterations in key osteogenic factors and dysfunction of bone marrow ...
  • The effects of mutant Ras proteins on the cell signalome 
    Takács, Tamás; Kudlik, Gyöngyi; Kurilla, Anita; Szeder, Bálint; Buday, László; Vas, V.irág (2020)
    The genetic alterations in cancer cells are tightly linked to signaling pathway dysregulation. Ras is a key molecule that controls several tumorigenesis-related processes, and mutations in RAS genes often lead to unbiased ...
  • The SH3 domain of Caskin1 binds to lysophosphatidic acid suggesting a direct role for the lipid in intracellular signaling 
    Koprivanacz, Kitti; Tőke, Orsolya; Besztercei, B; Juhász, Tünde; Radnai, László; Merő, Balázs László; Mihály, Judith; Péter, Mária; Balogh, Gábor; Vígh, László; Buday, László; Liliom, Károly (2017)
    Src homology 3 or SH3 domains constitute one of the most common protein domains in signal transduction, generally characterized by their binding to proline-rich sequences on interacting signaling proteins. Caskin1, a ...
  • The transcriptional activity of hepatocyte nuclear factor 4 alpha is inhibited via phosphorylation by ERK1/2 
    Vető, Borbála; Bojcsuk, Dóra; Bacquet C; Kiss J; Sipeki, Szabolcs; Martin L; Buday, László; Bálint, Bálint László; Arányi, Tamás (2017)
    Hepatocyte nuclear factor 4 alpha (HNF4alpha) nuclear receptor is a master regulator of hepatocyte development, nutrient transport and metabolism. HNF4alpha is regulated both at the transcriptional and post-transcriptional ...