The field of psychiatric genetics investigates the genetic background of psychiatric disorders. In a broader sense, this discipline aims to understand the molecular pathways underlying psychopathology, therefore, it is ...
Background: Recent evidences suggest that sex hormones may be involved in the regulation of exercise-induced left ventricular (LV) hypertrophy. However, the sex-specific functional consequences of exercise-induced myocardial ...
Dipeptidyl-peptidase 4 (DPP4) enzyme is involved in the degradation of many biologically active peptides including opioids. Its role in pain transmission is poorly elucidated. Recently we reported on the spinal antihyperalgesic ...
The reduced derivative of α-conotoxin MI, a 14 amino acid peptide is characterized by NMR-pH titrations and molecular dynamics simulations to determine the protonation constants of the nine basic moieties, including four ...
Ágg, Bence; Császár, Andrea; Szalay-Bekő, Máté; V. Veres, Dániel; Mizsei, Réka; Ferdinandy, Péter; Csermely, Péter; A. Kovács, István(2019)
Motivation: Network visualizations of complex biological datasets usually result in 'hairball' images, which do not discriminate network modules.
Results: We present the EntOptLayout Cytoscape plug-in based on a recently ...
The genetic analysis of early-onset Parkinsonian disorder (EOPD) is part of the clinical diagnostics. Several genes have been implicated in the genetic background of Parkinsonism, which is clinically indistinguishable from ...
Vera Alvarez, Roberto; Pongor, Lorinc Sandor; Mariño-Ramírez, Leonardo; Landsman, David(2019)
The quantification of RNA sequencing (RNA-seq) abundance using a normalization method that calculates transcripts per million (TPM) is a key step to compare multiple samples from different experiments. TPMCalculator is a ...