Folyóiratcikkek tallózása szerző szerint "Holland, Christian H"

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Robustness and applicability of transcription factor and pathway analysis tools on single-cell RNA-seq data

Holland, Christian H; Tanevski, Jovan; Perales-Patón, Javier; Gleixner, Jan; Kumar, Manu P; Mereu, Elisabetta; Joughin, Brian A; Stegle, Oliver; Lauffenburger, Douglas A; Heyn, Holger; Szalai, Bence; Saez-Rodriguez, Julio (2020)

Many functional analysis tools have been developed to extract functional and mechanistic insight from bulk transcriptome data. With the advent of single-cell RNA sequencing (scRNA-seq), it is in principle possible to do ...
Signatures of cell death and proliferation in perturbation transcriptomics data-from confounding factor to effective prediction

Szalai, Bence; Subramanian, Vigneshwari; Holland, Christian H; Alföldi, Róbert; Puskás, László; Saez-Rodriguez, Julio (2019)

Transcriptional perturbation signatures are valuable data sources for functional genomics. Linking perturbation signatures to screenings opens the possibility to model cellular phenotypes from expression data and to identify ...

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